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Protein Overview: blw-PA

General Information:
Name(s) found: blw-PA / FBpp0071794 [FlyBase]
Description(s) found:
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  • gi|7291477|gb|AAF46903.1| bellwether [Drosophila melanogaster] [NCBI NR]
  • gi|5921205|sp|P35381.2|ATPA_DROME RecName: Full=ATP synthase subunit alpha, mitochondrial; AltName: Full=Protein bellwether; Flags: Precursor [NCBI NR]
  • gi|28317168|gb|AAO39595.1| HL08087p [Drosophila melanogaster] [NCBI NR]
  • gi|24658560|ref|NP_726243.1| bellwether [Drosophila melanogaster] [NCBI NR]
  • gi|1556392|emb|CAA69202.1| mitochondrial ATP synthase alpha subunit precursor [Drosophila melanogaster] [NCBI NR]
  • ATP synthase subunit alpha, mitochondrial OS=Drosophila melanogaster GN=blw PE=1 SV=2 [Swiss-Prot]
  • The gene bellwether is referred to in FlyBase by the symbol Dmel\blw (CG3612, FBgn0011211). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18686559..18689691. It has the cytological map location 59B1-59B2. Based on sequence similarity, it is predicted to have molecular function</span>: hydrogen-exporting ATPase activity, phosphorylative mechanism. There is experimental evidence that it is involved in the biological process</span>: growth; spermatid development; phagocytosis, engulfment. 31 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3612-PA translation from_gene[CG3612 blw FBgn0011211] seq_release:3 mol_weight=59422 cds_boundaries:(2R:17,842,754..17,845,239[+]) aa_length:552 transcript_info:[CG3612-RA seq_release:3] gene_info:[gene symbol:blw FBgn0011211 gene_boundaries:(2R:17, [hmr_yeast5_DM3-1_pombe.fasta]
  • (P35381) ATP synthase alpha chain, mitochondrial precursor (EC 3.6.3.14) (Protein bellwether) [DrosMelano7227.FASTAC.txt]
  • (AE003458) blw gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG3612-PA [Drosophila melanogaster]gi|28317168|gb|AAO39595.1| HL08087p [Drosophila melanogaster]gi|24658560|ref|NP_726243.1| CG3612-PA [Drosophila melanogaster]gi|1556392|emb|CAA69202.1| mitochondrial ATP synthase alpha subunit precursor [Drosophila me [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(18686709..18686774,18687401..18687981,18688074..18688875,18688988..18689197); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:N [fly-100309-contam.fasta]
  • ATP synthase subunit alpha, mitochondrial precursor (Protein bellwether) [nr-271106-contam.fasta]
  • mitochondrial ATP synthase alpha subunit precursor [Drosophila melanogaster] [nr-271106-contam.fasta]
  • bellwether CG3612-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • HL08087p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3612-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(18686709..18686774,18687401..18687981,18688074..18688875,18688988..18689197); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(18686709..18686774,18687401..18687981,18688074..18688875,18688988..18689197); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2R:join(18686709..18686774,18687401..18687981,18688074..18688875,18688988..18689197); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903,FlyMine:FBpp0071794,modMine:FBpp0071794; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(22799204..22799269,22799896..22800476,22800569..22801370,22801483..22801692); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903,FlyMine:FBpp0071794,modMine:FBpp0071794; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(22799204..22799269,22799896..22800476,22800569..22801370,22801483..22801692); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903,FlyMine:FBpp0071794,modMine:FBpp0071794; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0071794 type=protein; loc=2R:join(22799204..22799269,22799896..22800476,22800569..22801370,22801483..22801692); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903,FlyMine:FBpp0071794,modMine:FBpp0071794; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(22799204..22799269,22799896..22800476,22800569..22801370,22801483..22801692); ID=FBpp0071794; name=blw-PA; parent=FBgn0011211,FBtr0071883; dbxref=FlyBase:FBpp0071794,FlyBase_Annotation_IDs:CG3612-PA,GB_protein:AAF46903.1,REFSEQ:NP_726243,GB_protein:AAF46903,UniProt/Swiss-Prot:P35381,FlyMine:FBpp0071794,modMine:FBpp0071794; MD5=9adab5c6a725023536c45cc02a2d2dad; length=552; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 552 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    mitochondrial proton-transporting ATP synthase complex, catalytic core F(1) [ISS]
    Biological Process: proton transport [ISS][NAS]
    phagocytosis, engulfment [IMP]
    spermatid development [IMP]
    growth [IMP]
    ATP synthesis coupled proton transport [IEA]
    Molecular Function: hydrogen-exporting ATPase activity, phosphorylative mechanism [ISS][NAS]
    proton-transporting ATPase activity, rotational mechanism [IEA]
    hydrogen ion transporting ATP synthase activity, rotational mechanism [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSIFSARLAS SVARNLPKAA NQVACKAAYP AASLAARKLH VASTQRSAEI SNILEERILG  60
   61 VAPKADLEET GRVLSIGDGI ARVYGLNNIQ ADEMVEFSSG LKGMALNLEP DNVGVVVFGN 120
  121 DKLIKQGDIV KRTGAIVDVP VGDELLGRVV DALGNAIDGK GAINTKDRFR VGIKAPGIIP 180
  181 RVSVREPMQT GIKAVDSLVP IGRGQRELII GDRQTGKTAL AIDTIINQKR FNEAQDESKK 240
  241 LYCIYVAIGQ KRSTVAQIVK RLTDSGAMGY SVIVSATASD AAPLQYLAPY SGCAMGEYFR 300
  301 DKGKHALIIY DDLSKQAVAY RQMSLLLRRP PGREAYPGDV FYLHSRLLER AAKMSPAMGG 360
  361 GSLTALPVIE TQAGDVSAYI PTNVISITDG QIFLETELFY KGIRPAINVG LSVSRVGSAA 420
  421 QTKAMKQVAG SMKLELAQYR EVAAFAQFGS DLDAATQQLL NRGVRLTELL KQGQYVPMAI 480
  481 EDQVAVIYCG VRGHLDKMDP AKITKFEKEF LQHIKTSEQA LLDTIAKDGA ISEASDAKLK 540
  541 DIVAKFMSTF QG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..552] PSI-BLAST 1000.0 No description for 2v7qA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.81

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle