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Protein Overview: CG17807-PA

General Information:
Name(s) found: CG17807-PA / FBpp0071849 [FlyBase]
Description(s) found:
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  • gi|7291441|gb|AAF46867.1| CG17807 [Drosophila melanogaster] [NCBI NR]
  • gi|24658267|ref|NP_611690.2| CG17807 [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG17807 (CG17807, FBgn0034748). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18521524..18523435. It has the cytological map location 58F2. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: methyltransferase activity; oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 5 alleles are reported. The phenotype of these alleles is annotated with: embryonic heart. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG17807-PA translation from_gene[CG17807 CG17807 FBgn0034748] seq_release:3 mol_weight=69295 cds_boundaries:(2R:17,677,630..17,679,474[-]) aa_length:615 transcript_info:[CG17807-RA seq_release:3] gene_info:[gene symbol:CG17807 FBgn0034748 gene_boundar [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W232) CG17807 protein [DrosMelano7227.FASTAC.txt]
  • (AE003458) CG17807 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG17807-PA [Drosophila melanogaster]gi|24658267|ref|NP_611690.2| CG17807-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(18521582..18523429); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867; MD5=456735837af7 [fly-100309-contam.fasta]
  • CG17807-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(18521582..18523429); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(18521582..18523429); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG17807 OS=Drosophila melanogaster GN=CG17807 PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(18521582..18523429); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867,FlyMine:FBpp0071849,modMine:FBpp0071849; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(22634077..22635924); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867,FlyMine:FBpp0071849,modMine:FBpp0071849; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(22634077..22635924); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867,FlyMine:FBpp0071849,modMine:FBpp0071849; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • CG17807 OS=Drosophila melanogaster GN=CG17807 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0071849 type=protein; loc=2R:complement(22634077..22635924); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867,FlyMine:FBpp0071849,modMine:FBpp0071849; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(22634077..22635924); ID=FBpp0071849; name=CG17807-PA; parent=FBgn0034748,FBtr0071938; dbxref=FlyBase:FBpp0071849,FlyBase_Annotation_IDs:CG17807-PA,GB_protein:AAF46867.1,REFSEQ:NP_611690,GB_protein:AAF46867,UniProt/TrEMBL:Q9W232,FlyMine:FBpp0071849,modMine:FBpp0071849; MD5=456735837af7c11b6a7f1df1a0ebf1b8; length=615; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 615 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: oxidoreductase activity [IEA]
    methyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVEETQQKV NKAKKADKKQ RRCLAIIKSD CEVSPSAEPT PYLAVLNVGL SNGLTEECLL  60
   61 TEAAATGGKV IQVVMLPGKS YCFFICASLE DSQLIYEGMH NISTIGQQGA VAYLSYIRQL 120
  121 PALAGKSEWN KPLPRGLHII ADFVTEEEES TLLRAIGEDG RTSEVTGSLK HRNVKHFGFE 180
  181 FLYGTNNVDP SKPLEQSIPS ACDILWPRLN SFASTWDWSS PDQLTVNEYE PGHGIPPHVD 240
  241 THSAFLDPIL SLSLQSDVVM DFRRGDDQVQ VRLPRRSLLI MSGEARYDWT HGIRPKHIDV 300
  301 VPSASGGLTT QARGKRTSLT FRRLRKGPCD CSYPALCDTQ QTKVPQELHA SLAAQAITLE 360
  361 QQNVHEVYDK IADHFSETRH TPWPQVSEFL DSFEPQSVVL DIGCGNGKYL SCNPLLLSVG 420
  421 CDRAQGLLAV GRRKGQNVFR CDCLVVPVRS SSIDGCISIA VIHHLATKER RLAALQEMAR 480
  481 VLRPGGRALV YVWAKDQRKN DKKSTYLRQN KAVNKERTTE QQQRQKQHQE LEQQLSNNNP 540
  541 LPVHTNRTEF QQQDVLVPWK TKDEQKTTYL RYYHVFEEQE LENLVSQVHE VQLIKSYYDQ 600
  601 GNHCAIFEKL SNNSL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] PSI-BLAST 30.522879 solution structure of RNA binding domain in Hypothetical protein LOC91801
    2 View Details [121..313] PSI-BLAST 30.0 Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T
    3 View Details [314..615] PSI-BLAST 22.69897 Crystal structure of Ubiquinone/menaquinone biosynthesis methyltransferase-related protein (tm1389) from THERMOTOGA MARITIMA at 2.35 A resolution

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • RNA binding
    		•  4.46119712758726 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.81920018903278 bayes_pls_golite062009
  • binding
    		•  3.44552682116509 bayes_pls_golite062009
  • mRNA binding
    		•  3.05425904007847 bayes_pls_golite062009
    		• 1.52879236550095 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.07788694919471 bayes_pls_golite062009
  • protein binding
    		•  1.02232785292059 bayes_pls_golite062009
  • DNA binding
    		•  0.978604858165557 bayes_pls_golite062009
  • single-stranded RNA binding
    		•  0.852368751354665 bayes_pls_golite062009
  • ligase activity
    		•  0.830310998838737 bayes_pls_golite062009
  • poly-pyrimidine tract binding
    		•  0.56829350502235 bayes_pls_golite062009
  • transcription factor activity
    		•  0.234742017105535 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.78258647804494 bayes_pls_golite062009
  • DNA binding
    		•  1.56354377166329 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.46516949160385 bayes_pls_golite062009
  • catalytic activity
    		•  0.921320409505 bayes_pls_golite062009
  • damaged DNA binding
    		•  0.48105109213734 bayes_pls_golite062009
  • protein binding
    		•  0.200706152890822 bayes_pls_golite062009
  • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
    		•  0.0573662038808485 bayes_pls_golite062009
    3
    Term Confidence Notes
  • methyltransferase activity
    		•  4.15445027778357 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  4.07806017452628 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  4.07153733729662 bayes_pls_golite062009
  • protein methyltransferase activity
    		•  3.92746815303714 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.39429041855776 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  3.07428840534971 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  2.99461585647365 bayes_pls_golite062009
  • transferase activity
    		•  2.926540904444 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  2.5931020126592 bayes_pls_golite062009
  • arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • protein-arginine N-methyltransferase activity
    		•  2.41876112831625 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  2.29640050660273 bayes_pls_golite062009
  • DNA-methyltransferase activity
    		•  2.18991764495147 bayes_pls_golite062009
  • histone-arginine N-methyltransferase activity
    		•  2.04296107639729 bayes_pls_golite062009
  • tRNA (cytosine-5-)-methyltransferase activity
    		•  1.88889414729709 bayes_pls_golite062009
  • tRNA (cytosine)-methyltransferase activity
    		•  1.88889414729709 bayes_pls_golite062009
  • protein-arginine omega-N monomethyltransferase activity
    		•  1.66871163498737 bayes_pls_golite062009
  • tRNA (adenine-N1-)-methyltransferase activity
    		•  1.29759910099835 bayes_pls_golite062009
  • tRNA (adenine)-methyltransferase activity
    		•  1.29759910099835 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • histone methyltransferase activity (H4-R3 specific)
    		•  1.1103522853299 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • protein-arginine omega-N asymmetric methyltransferase activity
    		•  0.89325812193225 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • binding
    		•  0.777596419415505 bayes_pls_golite062009
  • site-specific DNA-methyltransferase (adenine-specific) activity
    		•  0.703178429468566 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  0.533090627724779 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.455449410561251 bayes_pls_golite062009
  • RNA binding
    		•  0.417524996559564 bayes_pls_golite062009
  • protein-arginine omega-N symmetric methyltransferase activity
    		•  0.364369105571521 bayes_pls_golite062009
  • tRNA (guanine) methyltransferase activity
    		•  0.203168546434167 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle