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View Structure Prediction Details

Protein: CG17807-PA
Organism: Drosophila melanogaster
Length: 615 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CG17807-PA.

Description E-value Query
Range
Subject
Range
gi|17863052 - gi|17863052|gb|AAL40003.1| SD10403p [Drosophila melanogaster]
520.0 [0..1] [615..1]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVEETQQKV NKAKKADKKQ RRCLAIIKSD CEVSPSAEPT PYLAVLNVGL SNGLTEECLL  60
   61 TEAAATGGKV IQVVMLPGKS YCFFICASLE DSQLIYEGMH NISTIGQQGA VAYLSYIRQL 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.522879
Match: 2cq2A
Description: solution structure of RNA binding domain in Hypothetical protein LOC91801
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
RNA binding 4.46119712758726 bayes_pls_golite062009
nucleic acid binding 3.81920018903278 bayes_pls_golite062009
binding 3.44552682116509 bayes_pls_golite062009
mRNA binding 3.05425904007847 bayes_pls_golite062009
1.52879236550095 bayes_pls_golite062009
transcription regulator activity 1.07788694919471 bayes_pls_golite062009
protein binding 1.02232785292059 bayes_pls_golite062009
DNA binding 0.978604858165557 bayes_pls_golite062009
single-stranded RNA binding 0.852368751354665 bayes_pls_golite062009
ligase activity 0.830310998838737 bayes_pls_golite062009
poly-pyrimidine tract binding 0.56829350502235 bayes_pls_golite062009
transcription factor activity 0.234742017105535 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [121-313]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PALAGKSEWN KPLPRGLHII ADFVTEEEES TLLRAIGEDG RTSEVTGSLK HRNVKHFGFE  60
   61 FLYGTNNVDP SKPLEQSIPS ACDILWPRLN SFASTWDWSS PDQLTVNEYE PGHGIPPHVD 120
  121 THSAFLDPIL SLSLQSDVVM DFRRGDDQVQ VRLPRRSLLI MSGEARYDWT HGIRPKHIDV 180
  181 VPSASGGLTT QAR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 30.0
Match: 2fd8A
Description: Crystal Structure of AlkB in complex with Fe(II), 2-oxoglutarate, and methylated trinucleotide T-meA-T
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.78258647804494 bayes_pls_golite062009
DNA binding 1.56354377166329 bayes_pls_golite062009
nucleic acid binding 1.46516949160385 bayes_pls_golite062009
catalytic activity 0.921320409505 bayes_pls_golite062009
damaged DNA binding 0.48105109213734 bayes_pls_golite062009
protein binding 0.200706152890822 bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors 0.0573662038808485 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [314-615]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GKRTSLTFRR LRKGPCDCSY PALCDTQQTK VPQELHASLA AQAITLEQQN VHEVYDKIAD  60
   61 HFSETRHTPW PQVSEFLDSF EPQSVVLDIG CGNGKYLSCN PLLLSVGCDR AQGLLAVGRR 120
  121 KGQNVFRCDC LVVPVRSSSI DGCISIAVIH HLATKERRLA ALQEMARVLR PGGRALVYVW 180
  181 AKDQRKNDKK STYLRQNKAV NKERTTEQQQ RQKQHQELEQ QLSNNNPLPV HTNRTEFQQQ 240
  241 DVLVPWKTKD EQKTTYLRYY HVFEEQELEN LVSQVHEVQL IKSYYDQGNH CAIFEKLSNN 300
  301 SL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 22.69897
Match: 2avnA
Description: Crystal structure of Ubiquinone/menaquinone biosynthesis methyltransferase-related protein (tm1389) from THERMOTOGA MARITIMA at 2.35 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
methyltransferase activity 4.15445027778357 bayes_pls_golite062009
N-methyltransferase activity 4.07806017452628 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 4.07153733729662 bayes_pls_golite062009
protein methyltransferase activity 3.92746815303714 bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity 3.39429041855776 bayes_pls_golite062009
RNA methyltransferase activity 3.07428840534971 bayes_pls_golite062009
histone methyltransferase activity 2.99461585647365 bayes_pls_golite062009
transferase activity 2.926540904444 bayes_pls_golite062009
tRNA methyltransferase activity 2.5931020126592 bayes_pls_golite062009
arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
protein-arginine N-methyltransferase activity 2.41876112831625 bayes_pls_golite062009
rRNA methyltransferase activity 2.29640050660273 bayes_pls_golite062009
DNA-methyltransferase activity 2.18991764495147 bayes_pls_golite062009
histone-arginine N-methyltransferase activity 2.04296107639729 bayes_pls_golite062009
tRNA (cytosine-5-)-methyltransferase activity 1.88889414729709 bayes_pls_golite062009
tRNA (cytosine)-methyltransferase activity 1.88889414729709 bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity 1.66871163498737 bayes_pls_golite062009
tRNA (adenine-N1-)-methyltransferase activity 1.29759910099835 bayes_pls_golite062009
tRNA (adenine)-methyltransferase activity 1.29759910099835 bayes_pls_golite062009
catalytic activity 1.25333584501255 bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific) 1.1103522853299 bayes_pls_golite062009
transcription regulator activity 0.914549843668268 bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity 0.89325812193225 bayes_pls_golite062009
DNA binding 0.86027591375666 bayes_pls_golite062009
binding 0.777596419415505 bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity 0.703178429468566 bayes_pls_golite062009
nucleic acid binding 0.616949327277483 bayes_pls_golite062009
rRNA (adenine) methyltransferase activity 0.533090627724779 bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity 0.455449410561251 bayes_pls_golite062009
RNA binding 0.417524996559564 bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity 0.364369105571521 bayes_pls_golite062009
tRNA (guanine) methyltransferase activity 0.203168546434167 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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