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Protein Overview: CG3045-PA

General Information:
Name(s) found: CG3045-PA / FBpp0071700 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG3045 (CG3045, FBgn0034703). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18060310..18062243. It has the cytological map location 58C5. Based on sequence similarity, it is predicted to have molecular function</span>: pseudouridylate synthase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: pseudouridine synthesis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 499 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: pseudouridine synthesis [IEA]
    Molecular Function: RNA binding [IEA]
    pseudouridine synthase activity [IEA]
    pseudouridylate synthase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSATNDKKVV INKRLKGLSR EALEKLTQTE LIDKVIQLEA YNFQLRNLLQ KKLSEKDKHD  60
   61 KEYSGLIGNE AEGKVSQVAK TSSKVQKIRK FDWSSAHKRH VLLKITYFGW DYQGFACQED 120
  121 SNDTIESNLF RALARTCLIE SRATSNYHRC GRTDKEVSAF CQVISIDLRS KHPPESQLDP 180
  181 TALSSEIDYC GLLNRVLPKN IQCVAWMPLR SPVYSARFDC VSRTYRYYFP KGDLDIAAMR 240
  241 KACDLLVRHA DFRNFCKMDV HNGVTNYMRN LQSARVEACD QTNHTNSGYD MYYLEIQANA 300
  301 FLWHQIRCIM AVLLLVGQKK ENPGVISDLL DVESNPCKPQ YTPAIGLPLN LFRCDFRDHT 360
  361 TRSVNHPSSG DADEEAMDTA ADESNDLNAP EHLERDLTAW IYNEENLQKL IENTQCEWTQ 420
  421 FSVKSTMIRN VLQQLENLFE ENFKPKEKVL AQVILLQDSV NPRQYQPLLE RKRCESLENR 480
  481 IEHFVKKQRL IVKNETETE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] deduced N/A No confident structure predictions are available.
    2 View Details [98..365] PSI-BLAST 69.522879 No description for 2nqpA was found.
    3 View Details [366..499] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • pseudouridine synthase activity
    		•  5.60483019625575 bayes_pls_golite062009
  • intramolecular transferase activity
    		•  4.62815459483632 bayes_pls_golite062009
  • isomerase activity
    		•  3.43067391737824 bayes_pls_golite062009
  • catalytic activity
    		•  2.39224964671205 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle