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Protein Overview: NtR-PA

General Information:
Name(s) found: NtR-PA / FBpp0071676 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • The gene NtR is referred to in FlyBase by the symbol Dmel\NtR (CG6698, FBgn0029147). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18015313..18017693. It has the cytological map location 58B10-58C1. Based on sequence similarity, it is predicted to have molecular function</span>: excitatory extracellular ligand-gated ion channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: ion transport. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 585 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: ion transport [IEA]
    Molecular Function: excitatory extracellular ligand-gated ion channel activity [ISS]
    extracellular ligand-gated ion channel activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYNLIKGSLA TYCCLCLLLI LIDPAESGQL STRFNVSFAQ LDSCETYSVP NTGYGYRRFY  60
   61 MLRELSNNNR KAGERLHLKF YVLTAMDAHI LLSVTNHPRP NDRVYEIVIG AGGNTFSAIR 120
  121 NAMGMRRVAT NQEPNLVSLY DPTPIEIVQN QNGELFVYIP GFKKEPLLQF IDEAPLVINY 180
  181 LSFSSFGSNT ARWFYDCGFD GYGSEIAPIV KEETKTEKLL SHLNIQAENA SMPANLSSIS 240
  241 FHFQTRSLAY EQTSSLLQTR MHMMMHWRDS RLVWKPEDFG SLESFEHPDL RIWKPHMNVL 300
  301 NGALQSMGQV LQSYELMVYA NGSITLYAQN LQLASWCVDS ARNWPSERVT CDIELGLNGQ 360
  361 EGQENVALIY DDQRKPIAPN EHVNTPSGWS FTQMSVVLVE NDSQRRYNPK GMMQKMTGDV 420
  421 AIEFTLQRNR SFYMTVFYLP LIACQMFLIL SFVLRSTRRS SLILIALLIA AWGLMYMTRY 480
  481 ASPHYVPPMM TAYKVIMMTT TYCYILHICI IWLDLYPPRS KAPGWLVRVI NSNVLRCILG 540
  541 LRFSDSTDYC DIQENPWHHM AKILNNLSSI LVIITFAIVD ITSGF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] MSA 8.222979 View MSA. No confident structure predictions are available.
    2 View Details [199..585] PSI-BLAST 74.522879 Refined structure of the nicotinic acetylcholine receptor at 4A resolution.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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