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Protein Overview: GM130-PB

General Information:
Name(s) found: GM130-PB / FBpp0071702 [FlyBase]
Description(s) found:
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  • gi|24657676|ref|NP_726165.1| GM130, isoform B [Drosophila melanogaster] [NCBI NR]
  • gi|21626532|gb|AAF46804.2| GM130, isoform B [Drosophila melanogaster] [NCBI NR]
  • The gene GM130 is referred to in FlyBase by the symbol Dmel\GM130 (CG11061, FBgn0034697). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:18012075..18015002. It has the cytological map location 58B10. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: Golgi organization. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG11061-PB translation from_gene[CG11061 GM130 FBgn0034697] seq_release:3 mol_weight=86917 cds_boundaries:(2R:17,168,314..17,170,913[-]) aa_length:755 transcript_info:[CG11061-RB seq_release:3] gene_info:[gene symbol:GM130 FBgn0034697 gene_boundaries: [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9W290) CG11061 protein [DrosMelano7227.FASTAC.txt]
  • CG11061-PB, isoform B [Drosophila melanogaster]gi|24657676|ref|NP_726165.1| CG11061-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(18012265..18013086,18013146..18013658,18013714..18014529,18014650..18014709,18014811..18014867); ID=FBpp0071702; name=GM130-PB; parent=FBgn0034697,FBtr0071789; dbxref=FlyBase:FBpp0071702,FlyBase_Annotation_IDs:CG11061-PB,GB [fly-100309-contam.fasta]
  • GM130 CG11061-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG11061-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(18012265..18013086,18013146..18013658,18013714..18014529,18014650..18014709,18014811..18014867); ID=FBpp0071702; name=GM130-PB; parent=FBgn0034697,FBtr0071789; dbxref=FlyBase:FBpp0071702,FlyBase_Annotation_IDs:CG11061-PB,GB_protein:AAF46804.2,REFSEQ:NP_726165,GB_protein:AAF46804; MD5=a52ba2de51177cbe42f391ec52db6b7a; length=755; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(18012265..18013086,18013146..18013658,18013714..18014529,18014650..18014709,18014811..18014867); ID=FBpp0071702; name=GM130-PB; parent=FBgn0034697,FBtr0071789; dbxref=FlyBase:FBpp0071702,FlyBase_Annotation_IDs:CG11061-PB,GB_protein:AAF46804.2,REFSEQ:NP_726165,GB_protein:AAF46804; MD5=a52ba2de51177cbe42f391ec52db6b7a; length=755; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • GM130, isoform B OS=Drosophila melanogaster GN=GM130 PE=1 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(18012265..18013086,18013146..18013658,18013714..18014529,18014650..18014709,18014811..18014867); ID=FBpp0071702; name=GM130-PB; parent=FBgn0034697,FBtr0071789; dbxref=FlyBase:FBpp0071702,FlyBase_Annotation_IDs:CG11061-PB,GB_protein:AAF46804.2,REFSEQ:NP_726165,GB_protein:AAF46804,FlyMine:FBpp0071702,modMine:FBpp0071702; MD5=a52ba2de51177cbe42f391ec52db6b7a; length=755; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • GM130, isoform B OS=Drosophila melanogaster GN=GM130 PE=2 SV=2 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 755 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum [IDA]
    Golgi cis cisterna [ISS]
    Golgi stack [IDA]
    Biological Process: Golgi organization [IGI]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDDTQDAKA QKLAAARKKL KEYQQRASNN NGQPGAEEPQ SALPTAASYF AQNESEHNGG  60
   61 LADASSLQAI QVIIAEKAQL NAELTKVRLA CRERELELEE LRILKDQNQL RLEQLQQHCQ 120
  121 DQQSTGEQQR QQYAQLQAQL LQSQAQIKDQ QSHLNELEAQ LKQSNQHQEE LQQQLSQKSN 180
  181 ELEMAQLKLR QLSDESSVTT DNRVESLVQT QYMYEQQIRD LQAMVGQLTQ DKEQAAGQYQ 240
  241 NYVQHQSGEI AKLNERNTEL SEVLNSLRER ERQLVEHVGA LERDIQKNIS LQAQFKEASQ 300
  301 VQPSKEETSE QKALKDELAV LKEQIENFEF ERHEFQLKIK SQDDQLQLKN SALDELEKQL 360
  361 ERLQAEQPDQ SKLLATMESD KVAASRALTQ NVEMKNQLDE LQQRFVQLTN DKAELVIRLD 420
  421 SEEFANREIR QNYNSMEQKL QANEERFKFK DEEMIRLSHE NVELQRQQLM LQQQLDRLRH 480
  481 YEAKAYHAGE ETEKENGADA PENEAEEAKE VGLLHNHSHD HSHQHSDGHC HDNDHDHSHE 540
  541 HNHHNAGDHG HPHDHPHDHT HDHSHSHPHD HQHDHPHDHG QNHAHRQAAE TLPTAEAVER 600
  601 LQSRFTTLIS QVADLTEEKH SLEHLVLQLQ SETETIGEYI ALYQTQRRML KQREYEKAAQ 660
  661 MRLLQAEREQ LREKIEALNK LVVSLGVELP ADAAQAKQPE AAAGSEHTPG EGENSQQIIN 720
  721 KIQDIISEIK ENTEQPSHNH AGDHLNCCMG KFEVV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..292] PSI-BLAST 21.30103 Heavy meromyosin subfragment
    2 View Details [293..383] PSI-BLAST 3.69897 No description for 2iw5A was found.
    3 View Details [384..755] PSI-BLAST 11.30103 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.334577365229545 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0696342306231097 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle