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View Structure Prediction Details

Protein: GM130-PB
Organism: Drosophila melanogaster
Length: 755 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GM130-PB.

Description E-value Query
Range
Subject
Range
gi|68388302 - gi|68388302|ref|XP_696268.1| PREDICTED: similar to slow myosin heavy chain 1 [Danio rerio]
303.0 [0..41] [754..1845]

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Predicted Domain #1
Region A:
Residues: [1-292]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPDDTQDAKA QKLAAARKKL KEYQQRASNN NGQPGAEEPQ SALPTAASYF AQNESEHNGG  60
   61 LADASSLQAI QVIIAEKAQL NAELTKVRLA CRERELELEE LRILKDQNQL RLEQLQQHCQ 120
  121 DQQSTGEQQR QQYAQLQAQL LQSQAQIKDQ QSHLNELEAQ LKQSNQHQEE LQQQLSQKSN 180
  181 ELEMAQLKLR QLSDESSVTT DNRVESLVQT QYMYEQQIRD LQAMVGQLTQ DKEQAAGQYQ 240
  241 NYVQHQSGEI AKLNERNTEL SEVLNSLRER ERQLVEHVGA LERDIQKNIS LQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.30103
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [293-383]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQFKEASQVQ PSKEETSEQK ALKDELAVLK EQIENFEFER HEFQLKIKSQ DDQLQLKNSA  60
   61 LDELEKQLER LQAEQPDQSK LLATMESDKV A

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 2iw5A
Description: No description for 2iw5A was found.

Predicted functions:

Term Confidence Notes
binding 0.334577365229545 bayes_pls_golite062009
transcription regulator activity 0.0696342306231097 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [384-755]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ASRALTQNVE MKNQLDELQQ RFVQLTNDKA ELVIRLDSEE FANREIRQNY NSMEQKLQAN  60
   61 EERFKFKDEE MIRLSHENVE LQRQQLMLQQ QLDRLRHYEA KAYHAGEETE KENGADAPEN 120
  121 EAEEAKEVGL LHNHSHDHSH QHSDGHCHDN DHDHSHEHNH HNAGDHGHPH DHPHDHTHDH 180
  181 SHSHPHDHQH DHPHDHGQNH AHRQAAETLP TAEAVERLQS RFTTLISQVA DLTEEKHSLE 240
  241 HLVLQLQSET ETIGEYIALY QTQRRMLKQR EYEKAAQMRL LQAEREQLRE KIEALNKLVV 300
  301 SLGVELPADA AQAKQPEAAA GSEHTPGEGE NSQQIINKIQ DIISEIKENT EQPSHNHAGD 360
  361 HLNCCMGKFE VV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.30103
Match: 2tmaA
Description: Tropomyosin
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle