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Protein Overview: EfSec-PA

General Information:
Name(s) found: EfSec-PA / FBpp0071534 [FlyBase]
Description(s) found:
Found 21 descriptions.
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  • The gene EfSec is referred to in FlyBase by the symbol Dmel\EfSec (CG9841, FBgn0034627). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:17272060..17273720. It has the cytological map location 57E1. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity; translation elongation factor activity. There is experimental evidence that it is involved in the biological process</span>: translational readthrough. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 511 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: translational readthrough [IMP]
    translational elongation [ISS]
    Molecular Function: GTP binding [IEA]
    translation elongation factor activity [ISS]
    GTPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPINFNIGLL GHVDSGKTTL AKALSSISST AAFDKNPQSV ERGITLDLGF SGLLVDAPAH  60
   61 LPQGEQLQFT FVDCPGHASL IRTIIGGAQI IDLMLLVVDA QKGKQTQTAE CLIIGELLQK 120
  121 KLIVVINKID VYPENQRASK LEKLRLRLAK TLEATTFGGQ VPICAVSALQ GTHIAELREV 180
  181 LREAYFQPQR NLADPLFMYV DHCFGIKGQG TVCTGTLLQG KVQVNNVIEL PALGEQRKVK 240
  241 SIQMFRKNVT SASMGDRIGL CVTQFNAKLL ERGIITQPGY LKPIYAVCLQ FKPIRYYKEV 300
  301 IKSMRKMHIS VGHNTVMANV TLFRDTDGTT STFQLDKEYE YMEDVQPAEV QHNDVIYALL 360
  361 QFESPVLSPP HSTLIASKLD MDVHSTSCRL AFWGRIAWQT HSSKYFQEEL PKLRIFKRKQ 420
  421 KVGSIQRVVN SSEVIVQNLF KDAKRDLYVG KNVELSTGEK GRIERTFGQT SKVAITFQDA 480
  481 LSPETISNVK NVKVLLNCKK YVFNKQAGLF Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..511] PSI-BLAST 49.221849 Crystal structure of translation elongation factor SelB from Methanococcus maripaludis in complex with GDP

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • structural constituent of ribosome
    		•  3.73417106589645 bayes_pls_golite062009
  • structural molecule activity
    		•  3.37597574881709 bayes_pls_golite062009
  • translation elongation factor activity
    		•  3.34765067410136 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.01090004832643 bayes_pls_golite062009
  • translation initiation factor activity
    		•  2.37836841900859 bayes_pls_golite062009
  • translation regulator activity
    		•  2.20347076721097 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  2.18748808024313 bayes_pls_golite062009
  • binding
    		•  2.01866595777668 bayes_pls_golite062009
  • DNA binding
    		•  1.7904783386531 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.68903321260301 bayes_pls_golite062009
  • transcription factor activity
    		•  0.603758349693077 bayes_pls_golite062009
  • translation termination factor activity
    		•  0.269303802954244 bayes_pls_golite062009
  • translation release factor activity
    		•  0.252222008028593 bayes_pls_golite062009
  • protein binding
    		•  0.242047208982959 bayes_pls_golite062009
  • ATP binding
    		•  0.1860481660648 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  0.152859582615242 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  0.138615225841109 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle