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Protein Overview: CkIIbeta2-PA

General Information:
Name(s) found: CkIIbeta2-PA / FBpp0085590 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene Casein kinase II Ã?&#142;Ã?²2 subunit is referred to in FlyBase by the symbol Dmel\CkIIÃ?&#142;Ã?²2 (CG8914, FBgn0026136). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:16177132..16178056. It has the cytological map location 56F16. Based on sequence similarity, it is predicted to have molecular function</span>: protein kinase regulator activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein amino acid phosphorylation. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 219 amino acids

    Gene Ontology:
    Cellular Component: protein kinase CK2 complex [IEA][ISS][NAS]
    Biological Process: protein amino acid phosphorylation [ISS][NAS]
    Molecular Function: protein kinase activity [NAS]
    protein kinase regulator activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDSDESSWI HWFCKQRGNE FFCEVDEEYI QDKFNLNFLD SNVKNYKCAL EVILDLNPGS  60
   61 ASEDPAEPEL EASAEKLYGL IHARFILTNR GIELMLDKYN KGEFGTCPRA FCHSQPVLPI 120
  121 GLSDNPGEDM VRIYCPKCND VYIPKASRHS NLDGAFFGTG FPHMFFMEKP DARPKRAKQK 180
  181 FVPRLYGFKI HPTAYRTAAE IQKDVTMTPV GEIDSPSHI

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..219] PSI-BLAST 105.0 Casein kinase II beta subunit

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase regulator activity
    		•  4.14878012076359 bayes_pls_golite062009
  • kinase regulator activity
    		•  4.09603095102334 bayes_pls_golite062009
  • enzyme regulator activity
    		•  2.91779610785511 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.79245883940915 bayes_pls_golite062009
  • protein kinase activity
    		•  2.75473427458132 bayes_pls_golite062009
  • kinase activity
    		•  2.66515798949431 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.39333807060713 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  1.99491617326192 bayes_pls_golite062009
  • binding
    		•  1.85951177140712 bayes_pls_golite062009
  • transferase activity
    		•  1.77218599619559 bayes_pls_golite062009
  • protein binding
    		•  1.4657010373022 bayes_pls_golite062009
  • catalytic activity
    		•  0.2012862421225 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle