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Protein Overview: FBpp0309412, wbl-PA

General Information:
Name(s) found: FBpp0309412 [FlyBase]
wbl-PA / FBpp0085698 [FlyBase]
Description(s) found:
Found 31 descriptions.
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  • type=protein; loc=2R:join(15137330..15137605,15137810..15138307); ID=FBpp0309412; name=wbl-PB; parent=FBgn0004003,FBtr0340470; dbxref=FlyBase:FBpp0309412,FlyBase_Annotation_IDs:CG7225-PB; MD5=4333aa0c5991fbb853cbcd4eff1c1247; length=257; release=r5.56; species=Dmel; [FlyBase]
  • The gene windbeutel is referred to in FlyBase by the symbol Dmel\wbl (CG7225, FBgn0004003). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:15137266..15138419. It has the cytological map location 56C4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: protein targeting to Golgi; regulation of multicellular organism growth; protein processing. 9 alleles are reported. The phenotype of these alleles is annotated with: embryo. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 257 amino acids

    Gene Ontology:
    Cellular Component: endoplasmic reticulum lumen [IEA]
    endoplasmic reticulum [TAS]
    Biological Process: Toll signaling pathway [TAS]
    regulation of multicellular organism growth [IMP]
    protein targeting to Golgi [IGI][TAS]
    embryonic development ending in birth or egg hatching [TAS]
    protein processing [IGI]
    dorsal/ventral axis specification [NAS]
    protein secretion [IEA]
    maternal specification of dorsal/ventral axis, oocyte, soma encoded [TAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMHILVTLLL VAIHSIPTTW AVTCTGCVDL DELSFEKTVE RFPYSVVKFD IAYPYGEKHE  60
   61 AFTAFSKSAH KATKDLLIAT VGVKDYGELE NKALGDRYKV DDKNFPSIFL FKGNADEYVQ 120
  121 LPSHVDVTLD NLKAFVSANT PLYIGRDGCI KEFNEVLKNY ANIPDAEQLK LIEKLQAKQE 180
  181 QLTDPEQQQN ARAYLIYMRK IHEVGYDFLE EETKRLLRLK AGKVTEAKKE ELLRKLNILE 240
  241 VFRVHKVTKT APEKEEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..257] PSI-BLAST 33.69897 Crystal Structure and Functional Analysis of Drosophila Wind-- a PDI-Related Protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein disulfide isomerase activity
    		•  4.54149370439152 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  4.54149370439152 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  4.32416700334664 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.07184913651636 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  0.858243161645005 bayes_pls_golite062009
  • binding
    		•  0.828696005067827 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  0.44918717550973 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.229282171070161 bayes_pls_golite062009
  • protein binding
    		•  0.134341907247724 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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