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View Structure Prediction Details

Protein: FBpp0309412, wbl-PA
Organism: Drosophila melanogaster
Length: 257 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0309412, wbl-PA.

Description E-value Query
Range
Subject
Range
gi|114670980 - gi|114670980|ref|XP_001164327.1| PREDICTED: prolyl 4-hydroxylase, beta subunit isoform 5 [Pan troglo...
181.0 [0..18] [236..17]
PDIA1_PONAB - Protein disulfide-isomerase OS=Pongo abelii GN=P4HB PE=2 SV=1
PDIA1_PONPY - Protein disulfide-isomerase precursor - Pongo pygmaeus (Orangutan)
177.0 [0..2] [236..1]
gi|162461925, gi... - gi|59861271|gb|AAX09965.1| protein disulfide isomerase [Zea mays], gi|162461925|ref|NP_001105759.1| ...
177.0 [0..21] [243..144]
gi|7489183, gi|1... - pir||T03644 probable protein disulfide-isomerase (EC 5.3.4.1) precursor - common tobacco, gi|1848212...
175.0 [0..21] [242..138]
PDIA1_RABIT - Protein disulfide-isomerase OS=Oryctolagus cuniculus GN=P4HB PE=2 SV=1
175.0 [0..1] [236..1]
gi|92877262 - gi|92877262|gb|ABE84425.1| Thioredoxin domain 2 [Medicago truncatula]
174.0 [0..23] [242..145]
PDI22_ORYSJ - Protein disulfide isomerase-like 2-2 OS=Oryza sativa subsp. japonica GN=PDIL2-2 PE=2 SV=1
gi|125525761 - gi|125525761|gb|EAY73875.1| hypothetical protein OsI_01755 [Oryza sativa Indica Group]
174.0 [0..24] [243..152]
PDIA6_MEDSA - Probable protein disulfide-isomerase A6 OS=Medicago sativa PE=2 SV=1
173.0 [0..23] [242..145]
gi|77745442 - gi|77745442|gb|ABB02620.1| disulfide-isomerase precursor-like protein [Solanum tuberosum]
172.0 [0..24] [242..141]

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Predicted Domain #1
Region A:
Residues: [1-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMHILVTLLL VAIHSIPTTW AVTCTGCVDL DELSFEKTVE RFPYSVVKFD IAYPYGEKHE  60
   61 AFTAFSKSAH KATKDLLIAT VGVKDYGELE NKALGDRYKV DDKNFPSIFL FKGNADEYVQ 120
  121 LPSHVDVTLD NLKAFVSANT PLYIGRDGCI KEFNEVLKNY ANIPDAEQLK LIEKLQAKQE 180
  181 QLTDPEQQQN ARAYLIYMRK IHEVGYDFLE EETKRLLRLK AGKVTEAKKE ELLRKLNILE 240
  241 VFRVHKVTKT APEKEEL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1ovnA
Description: Crystal Structure and Functional Analysis of Drosophila Wind-- a PDI-Related Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein disulfide isomerase activity 4.54149370439152 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 4.54149370439152 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 4.32416700334664 bayes_pls_golite062009
disulfide oxidoreductase activity 1.07184913651636 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 0.858243161645005 bayes_pls_golite062009
binding 0.828696005067827 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
protein disulfide oxidoreductase activity 0.44918717550973 bayes_pls_golite062009
transcription regulator activity 0.229282171070161 bayes_pls_golite062009
protein binding 0.134341907247724 bayes_pls_golite062009

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