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Protein Overview: aft-PA

General Information:
Name(s) found: aft-PA / FBpp0088518 [FlyBase]
Description(s) found:
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  • gi|7302710|gb|AAF57788.1| adrift [Drosophila melanogaster] [NCBI NR]
  • gi|17137638|ref|NP_477413.1| adrift [Drosophila melanogaster] [NCBI NR]
  • Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 OS=Drosophila melanogaster GN=cmtr2 PE=2 SV=2 [Swiss-Prot]
  • The gene adrift is referred to in FlyBase by the symbol Dmel\aft (CG5032, FBgn0026309). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13673642..13676072. It has the cytological map location 54E9. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: methyltransferase activity; nucleic acid binding. There is experimental evidence that it is involved in the biological process</span>: open tracheal system development. 7 alleles are reported. The phenotype of these alleles is annotated with: embryonic/larval ganglionic branch. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG5032-PA translation from_gene[CG5032 aft FBgn0026309] seq_release:3 mol_weight=80504 cds_boundaries:(2R:12,849,928..12,852,135[+]) aa_length:700 transcript_info:[CG5032-RA seq_release:3] gene_info:[gene symbol:aft FBgn0026309 gene_boundaries:(2R:12, [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V887) AFT protein [DrosMelano7227.FASTAC.txt]
  • (AE003802) aft gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG5032-PA [Drosophila melanogaster]gi|17137638|ref|NP_477413.1| CG5032-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(13673708..13673749,13673805..13674245,13674299..13675918); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein [fly-100309-contam.fasta]
  • CG5032-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • adrift CG5032-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(13673708..13673749,13673805..13674245,13674299..13675918); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(13673708..13673749,13673805..13674245,13674299..13675918); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Adrift OS=Drosophila melanogaster GN=aft PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(13673708..13673749,13673805..13674245,13674299..13675918); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788,FlyMine:FBpp0088518,modMine:FBpp0088518; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • Adrift OS=Drosophila melanogaster GN=aft PE=4 SV=1 [UniProt_D_Melanogaster_07132012_07-13-2012_reversed.fasta]
  • type=protein; loc=2R:join(17786203..17786244,17786300..17786740,17786794..17788413); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788,FlyMine:FBpp0088518,modMine:FBpp0088518; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(17786203..17786244,17786300..17786740,17786794..17788413); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788,FlyMine:FBpp0088518,modMine:FBpp0088518; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0088518 type=protein; loc=2R:join(17786203..17786244,17786300..17786740,17786794..17788413); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788,FlyMine:FBpp0088518,modMine:FBpp0088518; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(17786203..17786244,17786300..17786740,17786794..17788413); ID=FBpp0088518; name=aft-PA; parent=FBgn0026309,FBtr0089549; dbxref=FlyBase:FBpp0088518,FlyBase_Annotation_IDs:CG5032-PA,GB_protein:AAF57788.1,REFSEQ:NP_477413,GB_protein:AAF57788,UniProt/Swiss-Prot:Q9UAS6,FlyMine:FBpp0088518,modMine:FBpp0088518; MD5=fcacb5780b27af4a6f250d0b6007dcb8; length=700; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 700 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][NAS][TAS]
    Biological Process: cell migration [NAS]
    tracheal outgrowth, open tracheal system [TAS]
    open tracheal system development [IEP][IMP][TAS]
    methylation [IEA]
    Molecular Function: nucleic acid binding [IEA]
    methyltransferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRSSPQGK PHPMTDYQSI RPSEVEQLFE KKFHYQKPKG NKSWQLPPPD QALFSEFYQF  60
   61 EALQGLREQL NAVKSKLNDY GVQEWSAHTN RRDPSGEVSW RLKNDTKAEF VTVAWCKLFE 120
  121 CLHRYPLVTK PAVNSMHLCE APGAFIASLN HYLHSKYEKD EIKWRWRSTT LNPYYEGNAI 180
  181 NQMISDDRFI VHTLDNWFFH KDLTGNLLDV ANIDHLVERC EVEFQGQVDL VTADGSIDCA 240
  241 AQPDCQEEIV VRLFFAEVLS ALRILSSGGN FLVKMFTLFE ACSVSLLYTL NCIFEEVHIF 300
  301 KPATSKRGNS EVYVICLNYN KDHPDLPRLL EEIKSKLAQP NDTLVMPLFA KFQIPHDFLM 360
  361 QHEIACRMYM KLQTDAIEGS IYAYESNDRH YLRHLHHLRS LVANTYYSLY KVKPLEDSLC 420
  421 IVDKEATSKA LGFQVPVYGG SYTERESLKH GDLLKQIYCL RREFNQLEKC LNNRTPYSYV 480
  481 KNRTAPLNLH ISRGAPVQSL QSSMFASEPI LILRLRILDT FELDPVWQSA PKCQLESKTL 540
  541 CYLPPTEDEA FHTAQQRFFI DLLEEVKKLK PDSIVFHKFL FLTHYAASLL LFLIESVYQD 600
  601 CCFNSNQAQT LTLSKLKDTA NSALEQVLEL LKDEQAGAIH SLLDIKELQK NQFSKALIQH 660
  661 NNSIVMTCFR SMLGEESFPM PVAPTSNSDV GSIQESAAVF

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..78] deduced N/A No confident structure predictions are available.
    2 View Details [79..322] PSI-BLAST 50.09691 RNA methyltransferase FtsJ
    3 View Details [323..481] MSA 2.139996 View MSA. No confident structure predictions are available.
    4 View Details [482..700] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • transferase activity
    		•  0.853574741278308 bayes_pls_golite062009
  • binding
    		•  0.539308706654818 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  0.352072576393216 bayes_pls_golite062009
  • methyltransferase activity
    		•  0.349480046648587 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle