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View Structure Prediction Details

Protein: aft-PA
Organism: Drosophila melanogaster
Length: 700 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for aft-PA.

Description E-value Query
Range
Subject
Range
gi|15150423 - gi|15150423|gb|AAK84935.1| SD02116p [Drosophila melanogaster]
703.0 [0..1] [700..1]

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Predicted Domain #1
Region A:
Residues: [1-78]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFRSSPQGK PHPMTDYQSI RPSEVEQLFE KKFHYQKPKG NKSWQLPPPD QALFSEFYQF  60
   61 EALQGLREQL NAVKSKLN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [79-322]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DYGVQEWSAH TNRRDPSGEV SWRLKNDTKA EFVTVAWCKL FECLHRYPLV TKPAVNSMHL  60
   61 CEAPGAFIAS LNHYLHSKYE KDEIKWRWRS TTLNPYYEGN AINQMISDDR FIVHTLDNWF 120
  121 FHKDLTGNLL DVANIDHLVE RCEVEFQGQV DLVTADGSID CAAQPDCQEE IVVRLFFAEV 180
  181 LSALRILSSG GNFLVKMFTL FEACSVSLLY TLNCIFEEVH IFKPATSKRG NSEVYVICLN 240
  241 YNKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.09691
Match: 1eizA
Description: RNA methyltransferase FtsJ
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity 0.853574741278308 bayes_pls_golite062009
binding 0.539308706654818 bayes_pls_golite062009
transferase activity, transferring one-carbon groups 0.352072576393216 bayes_pls_golite062009
methyltransferase activity 0.349480046648587 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [323-481]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPDLPRLLEE IKSKLAQPND TLVMPLFAKF QIPHDFLMQH EIACRMYMKL QTDAIEGSIY  60
   61 AYESNDRHYL RHLHHLRSLV ANTYYSLYKV KPLEDSLCIV DKEATSKALG FQVPVYGGSY 120
  121 TERESLKHGD LLKQIYCLRR EFNQLEKCLN NRTPYSYVK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [482-700]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRTAPLNLHI SRGAPVQSLQ SSMFASEPIL ILRLRILDTF ELDPVWQSAP KCQLESKTLC  60
   61 YLPPTEDEAF HTAQQRFFID LLEEVKKLKP DSIVFHKFLF LTHYAASLLL FLIESVYQDC 120
  121 CFNSNQAQTL TLSKLKDTAN SALEQVLELL KDEQAGAIHS LLDIKELQKN QFSKALIQHN 180
  181 NSIVMTCFRS MLGEESFPMP VAPTSNSDVG SIQESAAVF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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