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Protein Overview: Rab4-PB, Rab4-PA

General Information:
Name(s) found: Rab4-PA / FBpp0086009 [FlyBase]
Rab4-PB / FBpp0086008 [FlyBase]
Description(s) found:
Found 42 descriptions.
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  • The gene Rab-protein 4 is referred to in FlyBase by the symbol Dmel\Rab4 (CG4921, FBgn0016701). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13460579..13462484. It has the cytological map location 54C9-54C10. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. It is reported to be involved in the biological process</span>: endocytosis. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene Rab-protein 4 is referred to in FlyBase by the symbol Dmel\Rab4 (CG4921, FBgn0016701). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:13460579..13462484. It has the cytological map location 54C9-54C10. Based on sequence similarity, it is predicted to have molecular function</span>: GTPase activity. It is reported to be involved in the biological process</span>: endocytosis. 10 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 213 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: small GTPase mediated signal transduction [IEA]
    protein transport [IEA]
    endocytosis [TAS]
    Molecular Function: GTP binding [IEA]
    GTPase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSETYDYLFK FLIIGSAGSG KSCLLHHFIE SKFKDDSSHT IGVEFGSRIV NVGGKSVKLQ  60
   61 IWDTAGQERF RSVTRSYYRG AAGALLVYDA TSRDSFNALT NWLNDARTLA SPNIVILLVG 120
  121 NKKDLEEARD VTFLEASTFA QENELIFLET SAKTGENVEE AFLKCSKTIL AKIETGELDP 180
  181 ERIGSGIQYG GAALRNLQTR QRSINKPDCT CRV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..213] PSI-BLAST 54.0 high resolution structure of GDP-bound human Rab4a


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.78

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle