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Protein Overview: Picot-PB

General Information:
Name(s) found: Picot-PB / FBpp0086261 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene Picot is referred to in FlyBase by the symbol Dmel\Picot (CG8098, FBgn0024315). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:12542820..12555183. It has the cytological map location 53C15-53D1. Based on sequence similarity, it is predicted to have molecular function</span>: high affinity inorganic phosphate:sodium symporter activity. It is reported to be involved in the biological process</span>: phosphate transport. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 529 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA][NAS]
    Biological Process: transmembrane transport [IEA]
    phosphate transport [IEA][NAS]
    Molecular Function: high affinity inorganic phosphate:sodium symporter activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPFRRSSLNH RHRDGHVLVW NQRNLHESLE QQPQRCFATR YFVTFMLFLG MANAYVMRTN  60
   61 MSVAIVAMVN HTAIKSGEAE EYDDECGDRD IPIDDSQDGE FAWSSALQGY ILSSFFYGYV 120
  121 ITQIPFGILA KKYGSLRFLG YGMLINSVFA FLVPVAARGG GVWGLCAVRF IQGLGEGPIV 180
  181 PCTHAMLAKW IPPNERSRMG AAVYAGAQFG TIISMPLSGL LAEYGFDGGW PSIFYVFGIV 240
  241 GTVWSIAFLI FVHEDPSSHP TIDEREKKYI NDSLWGTDVV KSPPIPFKAI IKSLPFYAIL 300
  301 FAHMGHNYGY ETLMTELPTY MKQVLRFSLK SNGLLSSLPY LAMWLFSMFI SVVADWMISS 360
  361 KRFSHTATRK LINSIGQYGP GVALIAASYT GCDRALTLAI LTIGVGLNGG IYSGFKINHL 420
  421 DLTPRFAGFL MSITNCSANL AGLLAPIAAG HLISDPSKPM MGQWQIVFFI AAFVYIICGT 480
  481 FYNIFGSGER QYWDNPEDDE QKPALQTTVT TSPARLSNGS TAPAAISSS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..529] PSI-BLAST 45.154902 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • substrate-specific transmembrane transporter activity
    		•  5.46247398538901 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  4.58978526526921 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  4.31967711223954 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • anion transmembrane transporter activity
    		•  3.94605227012838 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • inorganic anion transmembrane transporter activity
    		•  2.52916479889426 bayes_pls_golite062009
  • organic acid transmembrane transporter activity
    		•  2.15783210522667 bayes_pls_golite062009
  • phosphate transmembrane transporter activity
    		•  1.78662033436109 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • binding
    		•  1.02928844080554 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  0.143419068761182 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  0.143419068761182 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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