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Protein Overview: bdg-PC, bdg-PA, ...

General Information:
Name(s) found: bdg-PC / FBpp0086435 [FlyBase]
bdg-PB / FBpp0086434 [FlyBase]
bdg-PA / FBpp0086433 [FlyBase]
Description(s) found:
Found 42 descriptions.
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  • The gene bedraggled is referred to in FlyBase by the symbol Dmel\bdg (CG8291, FBgn0034049). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11810545..11819434. It has the cytological map location 52D2. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. There is experimental evidence that it is involved in the biological process</span>: R3/R4 cell fate commitment. 10 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; antennal disc; eye photoreceptor cell; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene bedraggled is referred to in FlyBase by the symbol Dmel\bdg (CG8291, FBgn0034049). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11810545..11819434. It has the cytological map location 52D2. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. There is experimental evidence that it is involved in the biological process</span>: R3/R4 cell fate commitment. 10 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; antennal disc; eye photoreceptor cell; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • The gene bedraggled is referred to in FlyBase by the symbol Dmel\bdg (CG8291, FBgn0034049). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:11810545..11819434. It has the cytological map location 52D2. Based on sequence similarity, it is predicted to have molecular function</span>: neurotransmitter transporter activity. There is experimental evidence that it is involved in the biological process</span>: R3/R4 cell fate commitment. 10 alleles are reported. The phenotypes of these alleles are annotated with: eye disc; antennal disc; eye photoreceptor cell; ommatidium. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1331 amino acids

    Gene Ontology:
    Cellular Component: integral to plasma membrane [IEA]
    Biological Process: neurotransmitter transport [ISS]
    R3/R4 cell fate commitment [IGI][IMP]
    Molecular Function: neurotransmitter transporter activity [ISS]
    neurotransmitter:sodium symporter activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKEQQAAG RDFKRNSNAY SSLPPTGTGA GCSGAALGSG TGTGKRARSK QHQLEHEQFG  60
   61 LSNSLSSESI RQACAYYDDE LSDEDLIEIQ QTPQAFHQQT KQPLQLQPIS FRLGDELGDE 120
  121 RSAFCGSQEM QQVPLSTPIK QAAETDEALC VLSELDAILD VHDVSQLNGT CSSGSVNSGS 180
  181 DDDKVEDYLM DLDNYLEEMD NALNREDSLI IIDGHTSLKR EPRTRTLPLS RKKKSSKKKS 240
  241 EDQEAAQGDF QREHQLRKTF SCSLRPTSQI ASSSGSLETS TEPVMDVWRR QSMRRALEQE 300
  301 DTKATVAMER EEDDIPTLLV ELPPRRDAEM RRCFSQGDCQ ASVAPTVGSQ MLTEAHIFDN 360
  361 LLQTNARASS EEPRPRQYGR RLEGPPTPVR PLILAQSRPQ SAPTRVQMRE PQLQDTPTHP 420
  421 IMSTCSELSS ARSSRMPSPV SLPSDSSSSG SSSAEHDQEP DPVQTTTMCS ASSTTPLEPL 480
  481 HQLQLLLREK CGFNSQWPHA GSRTLALIGC TLGVFNMCRF AVLTINFGGN FLLQFLLLSV 540
  541 IFGIPLLWLQ MCLGAKIRAG PVSMWKISPI CAGVGIALVM QQCFLALYST VSLAWILVYL 600
  601 RDVFPTAARS GYRWQEMAFP YRYDASNATG NLTQTVAEYF NVVVLQRLHL ANHPDASGIR 660
  661 FHVNDRQLAF YLALIWAAVF LILCKGLKSL GKLAYIIYTL PLVALAVVTA KFVYVVDPSR 720
  721 IQNIFAASDF DDFLVNSNSW TAATQETFLT WGLLGASVIA ITSRSHTNAN KAALRRDAIL 780
  781 LVLFTLIGLG LMALLALCCA QILWQHGYVY VPGSFENPDC YTSIYSLQSN TNPYLLSYPR 840
  841 SLIPHYSSFI GETYRRNRTM IHVESGFQAL RFISEIFPAV LSLASDSISW VWAAVAFATF 900
  901 AGFGLAQLCV MWKPISSALG NSTSSVLLSC VTGLLLSIPF ATEMGISILY YVDFLLGGSW 960
  961 FIPIIWTAQI FGVFLIRGRP YNGDDLVNDL RLCGSMSAFL ALSWNVLLPI GLITLSVVDY1020
 1021 KASLSNQFYY WRGKSYFTYW SRKMGSLIQI GVLLVIPVTA IIQIYRYLAH GPPDILERIQ1080
 1081 LLYRPPEEGE EPRRPSARQT ASQSRRNALG QTTEGGQHDA QNDAPPKYTP PPSYTTATGA1140
 1141 RLAKLLRQSI RRSVRRVLGD SSRTRPVLSL DAESASPAAP PDYLTILTNP AGSSFNADPS1200
 1201 PASSSSPESI EIDQRPVGYS QRSQSLGRKL HRSGASTLER RPYTAEDVVT ILRSSVRHRQ1260
 1261 SQGGGNLVTA STLPRPPTAA MSTHLEDASF RSIENLVLNA EPPDRTPGVE LELELEAGQA1320
 1321 EECARNNTSV I

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..222] deduced N/A No confident structure predictions are available.
    2 View Details [223..464] deduced N/A No confident structure predictions are available.
    3 View Details [465..575] FFAS03 1.83 Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
    4 View Details [576..1122] PSI-BLAST 137.0 Mitochondrial cytochrome c oxidase, subunit I
    5 View Details [1123..1331] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • transporter activity
    		•  2.73170381418733 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  2.62482996567382 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.27184952386199 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.17385920299423 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  1.99291315963413 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.91328118970772 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  1.80711393777315 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  1.46596274907844 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  1.33785775698886 bayes_pls_golite062009
  • catalytic activity
    		•  0.295281150854022 bayes_pls_golite062009
  • binding
    		•  0.268640698115938 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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