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Protein Overview: BEAF-32-PA

General Information:
Name(s) found: BEAF-32-PA / FBpp0086571 [FlyBase]
Description(s) found:
Found 23 descriptions.
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  • The gene Boundary element-associated factor of 32kD is referred to in FlyBase by the symbol Dmel\BEAF-32 (CG10159, FBgn0015602). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10657975..10660135. It has the cytological map location 51C2. There is experimental evidence that it has the molecular function</span>: protein binding; DNA binding; chromatin insulator sequence binding. There is experimental evidence that it is involved in the biological process</span>: chromatin organization; regulation of transcription from RNA polymerase II promoter; oogenesis. 14 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye disc; eye; interommatidial bristle; egg chamber; ommatidium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 283 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    nuclear chromatin [IDA]
    Biological Process: oogenesis [IMP]
    chromatin organization [IMP]
    regulation of transcription from RNA polymerase II promoter [IDA]
    Molecular Function: DNA binding [IDA]
    protein binding [IPI]
    chromatin insulator sequence binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHVEKKSELR SLLKSGDKRC KLVEPRNTKS CVWRFFNLVQ CDDHIEPYAC CKTCGDLLSY  60
   61 SGKTGTGSLL RHRCLHSSSS NDKTVRITKA KTLREPLRVA KPKIESNVAN YLGEAGALPQ 120
  121 KWEEYEQNDE ISEDIKDIIY SEDPLCYSPI HVMDDEGLDQ PEKQVTVLTH STSPAGGSSR 180
  181 PIGVGSGVQA TVVASTSSSS SSAKQLKNNL ETSIERLTAV SEQLSYIIQQ NHEELTKDDD 240
  241 YYFALSLVPA MRHLSLSRKM YVRSKIQDIL FKESEDSTLA KDE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..142] FFAS03 1.73 No description for 2djrA was found.
    2 View Details [143..283] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle