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Protein Overview: L-PA

General Information:
Name(s) found: L-PA / FBpp0086621 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • The gene Lobe is referred to in FlyBase by the symbol Dmel\L (CG10109, FBgn0001332). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:10368708..10384817. It has the cytological map location 51A4. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: negative regulation of programmed cell death; eye-antennal disc development; compound eye development; negative regulation of Wnt receptor signaling pathway; negative regulation of JNK cascade; regulation of imaginal disc growth. 52 alleles are reported. The phenotypes of these alleles are annotated with: embryonic/first instar larval cuticle; eye disc; eye; antenna; extended germ band embryo; arista; ommatidium; head. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of imaginal disc growth [IMP]
    negative regulation of Wnt receptor signaling pathway [IMP]
    negative regulation of programmed cell death [IMP]
    negative regulation of JNK cascade [IMP]
    compound eye development [IMP]
    eye-antennal disc development [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLISCKCSNF VASTSKLQRS NSSSGAGGRV GGAEVASGEV PTAILLSQVF QQKYPLDFVF  60
   61 YSHIMEFFKH AYGPIPDLTV AVINQRELLY GLTLEAAGQS WQLSLCINCK EVLCAKRLTA 120
  121 GAGATPTLYL INCTLLTSSE ELAQRKSNKA FSETFELLIM DHTGSDSGST RPTSGLSNSA 180
  181 SSLSIGSLSS NPTDARVQRL RMIQAHQQAR LQEEIVETNE RIERYTRTQF QLLNSFREKS 240
  241 DQDCALLFKV IRALPEQASE LLDRAMLPAL DVAANQPQSA TARRRNTISS RRELNGGPTT 300
  301 PTTTLTHPPN FLSLNQQPQQ QLLAQQQQQQ LQAQQQQQQQ APQSVSMARK MSHFDTPPAT 360
  361 PEATPMSVGN SPTFRQQSAA GGAGGPPTQT LTPNGVGQSS VNEDADDCLF DLEDVDAPVP 420
  421 VQSVPVPSYT RSLIYQQQPQ HNPFQQLSQQ NGLRSVLDDE AADEAEDALD PDSSISIPVR 480
  481 GGGRPSHAQL MNFARSLPIE IANTTLAERA AVANNNNFGQ GCEEGMDNID IAASIQALTR 540
  541 SVHGEAVFGD LPRPRLRSQI EG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..189] deduced N/A No confident structure predictions are available.
    2 View Details [190..437] MSA 2.049996 View MSA. No confident structure predictions are available.
    3 View Details [438..562] MSA 2.033969 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.93

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle