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Protein Overview: fas-PA, FBpp0308965

General Information:
Name(s) found: FBpp0308965 [FlyBase]
fas-PA / FBpp0086751 [FlyBase]
Description(s) found:
Found 24 descriptions.
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  • type=protein; loc=2R:join(9541902..9541959,9593940..9594703,9600634..9600811,9601268..9601494,9602222..9602378,9605883..9606022,9606591..9606720,9613051..9613179,9613583..9613783,9633668..9633846,9633911..9634216); ID=FBpp0308965; name=fas-PB; parent=FBgn0000633,FBtr0339940; dbxref=FlyBase:FBpp0308965,FlyBase_Annotation_IDs:CG17716-PB; MD5=8937cbfc94b6b0a57246ce9a178b2b99; length=822; release=r5.56; species=Dmel; [FlyBase]
  • The gene faint sausage is referred to in FlyBase by the symbol Dmel\fas (CG17716, FBgn0000633). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9510593..9636882. It has the cytological map location 50B6-50C3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: morphogenesis of an epithelium; dorsal closure; Malpighian tubule morphogenesis; foregut morphogenesis; cardioblast cell fate determination; head involution; salivary gland development. 20 alleles are reported. The phenotypes of these alleles are annotated with 22 unique terms, many of which group under: embryonic nervous system; organ system; anatomical structure; embryonic neuron; primordium; nervous system; embryonic glial cell; embryonic head; ectoderm derivative; spiracle; commissure; midgut constriction. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 822 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: dorsal closure [IMP]
    morphogenesis of an epithelium [IMP][TAS]
    foregut morphogenesis [IMP]
    maintenance of polarity of embryonic epithelium [TAS]
    head involution [IMP]
    Malpighian tubule morphogenesis [IMP]
    cardioblast cell fate determination [IMP]
    salivary gland development [IMP]
    salivary gland morphogenesis [TAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRPTFDRRLW ILLFIISVQC TTYTQPQNIN AKSVQKPKPS ERREVISTSS SSSHSWPSIS  60
   61 AEPADEVVDH RGGGKPAKCA KNCQKAKAKW AKWRTQLKPH HQAHRAVQHK EARQRQRRET 120
  121 EEDELDAVLR APSSTSTSTA VATTVQATSS SSSATRSSVI NETKAKRPRS TLHLAPEDMQ 180
  181 PKPKEPVIII DDVEEFDSGT STSDLIARKS REEAEEEEDE GPLEPRVLPL RPVPPNPYEA 240
  241 EEMSVVYAEQ HSEIKLMCEV DLDIATSMWY KNGQVVHAMD RTARVTDYRF IKEANGALTI 300
  301 TNVMLEDDGK WQCEAENTRR YTENARPVKL VVLDRPKPPY LLIDSRRLDA SNLFVPVKEN 360
  361 SELNLACVSE GGNPRPTLTW EVLLSPGVDR HAQKVSAEVL ELEEIKGEKL DKDGYKINSG 420
  421 AKSEARLPAV YRAHHNARIL CVMEHPTLKI RQNASLLLDV QYTPSFAISR TPGFGYPLRE 480
  481 GIEVSLKCDV DSNPPSTPRW QKDDGDTPVP QTGDGFLNFT SIRREHSGWY KCTSRHLNFQ 540
  541 YSSIGYYLSV RFDSVDVTSE PDDQDVSVAA ASHNPNKGQL EVQLGGAVTL QCPQGSLGCW 600
  601 SHLDPISARL RGLGYGSSQP TGQFSLKDVM YQDAGMYKCV GQSPTNKKKL EVLQSVTVSV 660
  661 KGAPTVMALN ATPVAYPGSP LHLNVEFCAN PPAHAARWLH GDRVFTPGNQ YGTTVLAYAV 720
  721 KDLPTPFCKE ARLTYVSMHE RVPRTFYFIV STPGGVAEAI FNVNFTKRHR QLSNSIDDDE 780
  781 EEELNRPEQI HFPVFNGSPA DGRGWWAVVL ALLLVVATTN RH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..663] PSI-BLAST 61.221849 Model of human carcinoembryonic antigen by homology modelling and curve-fitting to experimental solution scattering data
    2 View Details [664..822] PSI-BLAST 37.0 Crystal Structure of the 3 Ig form of FGFR3c in complex with FGF1

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.68891223191024 bayes_pls_golite062009
  • protein binding
    		•  0.482552894534257 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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