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Protein Overview: Dh31-R1-PA

General Information:
Name(s) found: Dh31-R1-PA / FBpp0086868 [FlyBase]
Description(s) found:
Found 18 descriptions.
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  • The gene Diuretic hormone 31 receptor 1 is referred to in FlyBase by the symbol Dmel\Dh31-R1 (CG32843, FBgn0052843). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:9155302..9183429. It has the cytological map location 49F15-50A1. There is experimental evidence that it has the molecular function</span>: diuretic hormone receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: G-protein coupled receptor protein signaling pathway. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 443 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    integral to membrane [ISS]
    Biological Process: G-protein coupled receptor protein signaling pathway [IEA][ISS]
    cell surface receptor linked signaling pathway [IEA]
    Molecular Function: neuropeptide receptor activity [ISS]
    calcitonin receptor activity [ISS]
    diuretic hormone receptor activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDQIGNPNA TFSGSGSGSG TNVASIAESV AESGPDFDAL RAACETRLNA SGQLAGSGGP  60
   61 GAEAGTHCAG TFDGWLCWPD TAVGTSAYEL CPDFITGFDP ARYAHKECGL DGEWFKHPLT 120
  121 NKTWSNYTTC VNLEDLNWRH TVNLISEVGY GTSLLAILLS LAILGYFKSL KCARITLHMN 180
  181 LFASFAANNS LWLVWYLLVM PNSELLHQSP MRCVALHITL HYFLLSNYSW MLCEGFYLHT 240
  241 VLVAAFISEK RLVKWLIAFG WGSPAIVIFV YSMARGLGGT PEDNRHCWMN QTNYQNILMV 300
  301 PVCISMFLNL LFLCNIVRVV LLKLNAPASI QGSCGPSRTV LQAFRATLLL VPLLGLQYIL 360
  361 TPFRPAPKHP WENTYEIISA FTASFQGLCV AILFCFCNGE VIAQMKRKWR MMCFSNRPRT 420
  421 NSYTATQVSF VRCGPPLPGE EKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..117] PSI-BLAST 18.0 No description for 2jodA was found.
    2 View Details [118..443] PSI-BLAST 50.522879 Rhodopsin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • G-protein coupled receptor activity
    		•  7.11838006478957 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  5.41031049482732 bayes_pls_golite062009
  • receptor activity
    		•  5.12318570081263 bayes_pls_golite062009
  • signal transducer activity
    		•  4.16951678107564 bayes_pls_golite062009
  • molecular transducer activity
    		•  4.16951678107564 bayes_pls_golite062009
  • pituitary adenylate cyclase-activating polypeptide receptor activity
    		•  3.02091097474769 bayes_pls_golite062009
  • binding
    		•  1.48001943103409 bayes_pls_golite062009
  • peptide binding
    		•  1.37672683415634 bayes_pls_golite062009
  • growth hormone-releasing hormone receptor activity
    		•  0.621179725102141 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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