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Protein Overview: CG8834-PA

General Information:
Name(s) found: CG8834-PA / FBpp0087065 [FlyBase]
Description(s) found:
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  • gi|7303457|gb|AAF58513.1| CG8834, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24653035|ref|NP_610779.1| CG8834, isoform A [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8834 (CG8834, FBgn0033733). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8307316..8309988. It has the cytological map location 49A4. Based on sequence similarity, it is predicted to have molecular function</span>: 4-coumarate-CoA ligase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG8834-PA translation from_gene[CG8834 CG8834 FBgn0033733] seq_release:3 mol_weight=58960 cds_boundaries:(2R:7,485,363..7,487,196[-]) aa_length:535 transcript_info:[CG8834-RA seq_release:3] gene_info:[gene symbol:CG8834 FBgn0033733 gene_boundaries:(2R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V6B5) CG8834 protein [DrosMelano7227.FASTAC.txt]
  • (AE003822) CG8834 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8834-PA [Drosophila melanogaster]gi|24653035|ref|NP_610779.1| CG8834-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(8308152..8309106,8309165..8309281,8309342..8309528,8309585..8309792,8309848..8309988); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:A [fly-100309-contam.fasta]
  • CG8834-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(8308152..8309106,8309165..8309281,8309342..8309528,8309585..8309792,8309848..8309988); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(8308152..8309106,8309165..8309281,8309342..8309528,8309585..8309792,8309848..8309988); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG8834, isoform A OS=Drosophila melanogaster GN=CG8834 PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:complement(8308152..8309106,8309165..8309281,8309342..8309528,8309585..8309792,8309848..8309988); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513,FlyMine:FBpp0087065,modMine:FBpp0087065; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(12422343..12422483,12422080..12422287,12421837..12422023,12421660..12421776,12420647..12421601)); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513,FlyMine:FBpp0087065,modMine:FBpp0087065; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(12422343..12422483,12422080..12422287,12421837..12422023,12421660..12421776,12420647..12421601)); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513,FlyMine:FBpp0087065,modMine:FBpp0087065; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of A8DYB6, CG8834, isoform A OS=Drosophila melanogaster GN=CG8834 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0087065 type=protein; loc=2R:complement(join(12422343..12422483,12422080..12422287,12421837..12422023,12421660..12421776,12420647..12421601)); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513,FlyMine:FBpp0087065,modMine:FBpp0087065; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(12422343..12422483,12422080..12422287,12421837..12422023,12421660..12421776,12420647..12421601)); ID=FBpp0087065; name=CG8834-PA; parent=FBgn0033733,FBtr0087954; dbxref=FlyBase:FBpp0087065,FlyBase_Annotation_IDs:CG8834-PA,GB_protein:AAF58513.1,REFSEQ:NP_610779,GB_protein:AAF58513,UniProt/TrEMBL:A1Z8Z9,FlyMine:FBpp0087065,modMine:FBpp0087065; MD5=647486429f42c06bfe46c82031bd97c1; length=535; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 535 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: metabolic process [IEA]
    Molecular Function: 4-coumarate-CoA ligase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAMIPTTYNE KDNIWSGAKR NSIYNYDTSV GKIIFNNMKN WPKNVCQICD VDGVTVTFEQ  60
   61 GLTWSIRIAQ YLKKRGLNHK DVIGIAAKNS TYVMPLGVAC LMNGTPFHSV NPVLDDATLT 120
  121 HVFSITKPTL IFCDGQEYDK VHKATVGWHP EILTLTDHVE GVQGIETLLD PTTTEKIYQP 180
  181 EVLKEGGDQT VAILCSSGTT GLPKAVCISN SILIQDSMLI TSQSVIYVGS CLDWITGLWA 240
  241 FVFSTVFGCT RIISNKAFTP EYFVGLVKKY KINYAVLPPR HLSALITCPD AKPDALAPIT 300
  301 HLNYGGGSIS LATLQRSQEL CKTAMFNSGY GMTEVGAITI NIGISNVSSA GRPVPGIKIR 360
  361 IVDEDGKSLG YNQVGEIYVH TGQAWNGYYG NPVETRRMQD FEGWFHTGDL GYFDEQNFLY 420
  421 IVDRKKEILK YNGLHYWPTE IETVIAELSQ VQDVCVVGIY DEREGDAAGA LVVKSKGATI 480
  481 SAKEIVEHVA KRLPATQKQL RAGVQFTDKL PANVNGKTMR KTARDVFVAL RVSGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..535] PSI-BLAST 114.0 FIREFLY LUCIFERASE IN COMPLEX WITH BROMOFORM

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming carbon-sulfur bonds
    		•  5.10123876514454 bayes_pls_golite062009
  • fatty acid ligase activity
    		•  4.83067429373059 bayes_pls_golite062009
  • long-chain fatty acid-CoA ligase activity
    		•  4.72692389032116 bayes_pls_golite062009
  • acetate-CoA ligase activity
    		•  4.48129067128523 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  4.28278725989432 bayes_pls_golite062009
  • CoA-ligase activity
    		•  4.12850865352867 bayes_pls_golite062009
  • oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of one atom of oxygen (internal monooxygenases or internal mixed function oxidases)
    		•  2.74744781333102 bayes_pls_golite062009
  • Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing) activity
    		•  2.74744781333102 bayes_pls_golite062009
  • luciferin monooxygenase activity
    		•  2.67396462766343 bayes_pls_golite062009
  • ligase activity
    		•  2.49556073715112 bayes_pls_golite062009
  • catalytic activity
    		•  1.83545185797733 bayes_pls_golite062009
  • AMP binding
    		•  0.778227294974491 bayes_pls_golite062009
  • binding
    		•  0.509078620937952 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  0.464663038956639 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle