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Protein Overview: CG8858-PA

General Information:
Name(s) found: CG8858-PA / FBpp0087116 [FlyBase]
Description(s) found:
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  • gi|7303499|gb|AAF58554.1| CG8858 [Drosophila melanogaster] [NCBI NR]
  • gi|61213028|sp|Q9V677.1|ECM29_DROME RecName: Full=Proteasome-associated protein ECM29 homolog [NCBI NR]
  • gi|19922080|ref|NP_610746.1| CG8858 [Drosophila melanogaster] [NCBI NR]
  • Proteasome-associated protein ECM29 homolog OS=Drosophila melanogaster GN=CG8858 PE=1 SV=1 [Swiss-Prot]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8858 (CG8858, FBgn0033698). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:8079872..8086343. It has the cytological map location 48E8. Based on sequence similarity, it is predicted to have molecular function</span>: protein binding. Based on sequence similarity, it is predicted to be involved in the biological process</span>: protein catabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8858-PA translation from_gene[CG8858 CG8858 FBgn0033698] seq_release:3 mol_weight=212089 cds_boundaries:(2R:7,257,289..7,263,543[-]) aa_length:1890 transcript_info:[CG8858-RA seq_release:3] gene_info:[gene symbol:CG8858 FBgn0033698 gene_boundaries:( [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V677) CG8858 protein (GH27092p) [DrosMelano7227.FASTAC.txt]
  • (AE003823) CG8858 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG8858-PA [Drosophila melanogaster]gi|19922080|ref|NP_610746.1| CG8858-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:complement(8080078..8081523,8081578..8082809,8082875..8083513,8083579..8083941,8083995..8084461,8084524..8085009,8085065..8085945,8086052..8086182,8086308..8086335); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxr [fly-100309-contam.fasta]
  • Proteasome-associated protein ECM29 homolog [nr-271106-contam.fasta]
  • CG8858-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:complement(8080078..8081523,8081578..8082809,8082875..8083513,8083579..8083941,8083995..8084461,8084524..8085009,8085065..8085945,8086052..8086182,8086308..8086335); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:complement(8080078..8081523,8081578..8082809,8082875..8083513,8083579..8083941,8083995..8084461,8084524..8085009,8085065..8085945,8086052..8086182,8086308..8086335); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2R:complement(8080078..8081523,8081578..8082809,8082875..8083513,8083579..8083941,8083995..8084461,8084524..8085009,8085065..8085945,8086052..8086182,8086308..8086335); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554,FlyMine:FBpp0087116,modMine:FBpp0087116; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:complement(join(12198803..12198830,12198547..12198677,12197560..12198440,12197019..12197504,12196490..12196956,12196074..12196436,12195370..12196008,12194073..12195304,12192573..12194018)); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554,FlyMine:FBpp0087116,modMine:FBpp0087116; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:complement(join(12198803..12198830,12198547..12198677,12197560..12198440,12197019..12197504,12196490..12196956,12196074..12196436,12195370..12196008,12194073..12195304,12192573..12194018)); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554,FlyMine:FBpp0087116,modMine:FBpp0087116; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • FBpp0087116 type=protein; loc=2R:complement(join(12198803..12198830,12198547..12198677,12197560..12198440,12197019..12197504,12196490..12196956,12196074..12196436,12195370..12196008,12194073..12195304,12192573..12194018)); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554,FlyMine:FBpp0087116,modMine:FBpp0087116; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:complement(join(12198803..12198830,12198547..12198677,12197560..12198440,12197019..12197504,12196490..12196956,12196074..12196436,12195370..12196008,12194073..12195304,12192573..12194018)); ID=FBpp0087116; name=CG8858-PA; parent=FBgn0033698,FBtr0088008; dbxref=FlyBase:FBpp0087116,FlyBase_Annotation_IDs:CG8858-PA,GB_protein:AAF58554.1,REFSEQ:NP_610746,GB_protein:AAF58554,UniProt/Swiss-Prot:Q9V677,FlyMine:FBpp0087116,modMine:FBpp0087116; MD5=0eb83a9f0ba5aad861a29a3a95fa6a83; length=1890; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 1890 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS]
    cytoplasm [ISS]
    proteasome complex [ISS]
    Biological Process: protein catabolic process [ISS]
    Molecular Function: protein binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METGPNAEIE LLERVLLRLG NADSDEKLEA AVGKFLTPVI LKMNSPHNVV RTKVVEVLTH  60
   61 IKRRLSSRGH VQIPVEALLD QYAAQDSSTF LKNFAIIFIT MGFPRLALEQ QTALASKVVG 120
  121 CEDKLESYQD KLFALLLPVL SDMKIPDDPT QRSKLLDLQD KPAICANFLA LLQDVLLLPY 180
  181 GITQEQDVPP GLSPYSFTRI IAYNWRAEEL EKVKKGIVRF LCASVFSDLQ IFVPLVVASA 240
  241 DTRFSVATPA ITELSKLCTM LDFSNPAVTA PLYTLFAGNQ SKITDRQTRP CCARVRQKLL 300
  301 QYLIKCRGKS INVTKGLQVT FDGFFGTNTN QKCKVLALQF MELLLRDGPR ELVSKVSKVI 360
  361 LTGITKIIGR DSNEPNDVQN AAYSALAQHA RSFPQDVSQD LKLVLGYFNN LASCAPELHS 420
  421 SIREALVSMA PAFAWKTKEK SDAMEVDKNV DSSSVKLDGQ QHLLLAMLLD NAESKVQIVQ 480
  481 NVTSVFLTSC YPEYYAPARY LLLLIAGERN SLRENVTTYL YGTSKKDHIN YSMLSSIDHS 540
  541 KNRISSESIS DFNHLSLEQR RVMLPSFQVM MSHVHEMAEK RLKKNTACVV VGRTKLPYSL 600
  601 EVYEELLDYL RLCLWYSAGV VAAPGDEKYT HELREYITLH YEDTEDNALH QYAQFVQRSV 660
  661 EAKRSESNLI CLYDLLNAAP ELFAAKQLHL LEPLGNTLKD VSETMRINVA QVYGILWAFG 720
  721 LSDEKFDEEV GECLNSLTQK TLEHKHGWLL VVGHTFNRKI AMLKQENKTK DFAAWPQFVN 780
  781 AVKIISKCLC ESQWLLVSAA VKCISMIGKA VEIPNVPVEI QVPSKDGDDD DEEMTEYTSI 840
  841 DSSTKLVIFG VVFQLLRSSS ARQKIREDSA RCLGYLAIGD GEHFTKRNLD KFLTLTKIQK 900
  901 DAALNIAISE AIVNTLCGYD VNKGQPDEKF VNKHCNDDDF DQFLNSLIRL VTDPNPHSRQ 960
  961 AISVWLLAVV KHCSQRPAVL AKKELLQFAF TELLSDDSEF VQDVASRGLG LVYSISDSGS1020
 1021 QSDLANSLLD QLIGGKRKVN QVTADTELFA EGMLGKTPTG GNITTYKELC SLASDLNQPD1080
 1081 MIYQFMQLAN HNATWTSKLG AAFGLKTLSA ESRQKMEPYL GKIIPRLYRY KYDPTPKIQN1140
 1141 SMISIWDTIV TDSKEVTERY YWEILRELLD NLTCKEWRVR IACCLAVRDL LNRPNGLKLR1200
 1201 SEEPVRRALP DNSMEVDEVP EPELKELWFQ LFRVMDDIHE GTRVAAHGTA SFLGKLCVIA1260
 1261 SSSDHGKSGT AVASSILPFL LETGVGHKVP EIRRVSIKTI SDMIDSSGSL IAPHLATLIP1320
 1321 CLLRATGELE NTKLSYVSTR LGADNEAQEA VDTLRAEAAK SLHTMETIGK CVRYIDYSVL1380
 1381 EKMTPEVLEL MKGSVNLGTK IGCAHFVCLI SIRLGKEMTP LVGKYIRACF VGIKNRNATV1440
 1441 RKYNASAIGH LLGLAKEQSI KSLFTKLEEL YAEQPGNRSI ALTIQSINKR HHELLKDYMD1500
 1501 SMLPLIFFAM HEEPNEETKA NVELWKDLWH DVSPGDAGIR LNLNVIIPKL ESSLTDASWS1560
 1561 RKAQAANAIQ TIATRLSSSL DEPDRLRLIK LLLSGLQGRT FEGKERLLQA LAALTKGLDR1620
 1621 NHQICSSIID AAMREARKRE PVYRTMALAS LGEILDQLEA DRFEEVYNMS WNLLEKKELR1680
 1681 KESDDEDEPN TSQELSADER NKRAQTLNRL KEVVWETLGK SWPRHSIETQ HRYQLFFAEN1740
 1741 CTSILAESTR PVQVSLLAAL TKYIERLHVF DESAQVPDLT QINQEKKIKT EETAPKTREA1800
 1801 IVEKICTDVL AAVALAAGVP HSGLKKEALN IVLMLIKRLS GSGNGNQQPL RLIKQSFESN1860
 1861 LEKFQRDSAP EIRCRIKDIE DKLSKLNPQN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..203] MSA 2.081967 View MSA. No confident structure predictions are available.
    2 View Details [204..325] deduced N/A No confident structure predictions are available.
    3 View Details [326..701] PSI-BLAST 3.154902 AP1 clathrin adaptor core
    4 View Details [702..1598] PSI-BLAST 86.221849 No description for 2ot8A was found.
    5 View Details [1599..1890] PSI-BLAST 54.09691 No description for 2ie3A was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.87

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle