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Protein Overview: cuff-PA

General Information:
Name(s) found: cuff-PA / FBpp0087141 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene cutoff is referred to in FlyBase by the symbol Dmel\cuff (CG13190, FBgn0260932). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7773572..7775108. It has the cytological map location 48C5. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: dorsal/ventral pattern formation; ovarian fusome organization; oogenesis; germarium-derived female germ-line cyst formation; karyosome formation. 14 alleles are reported. The phenotypes of these alleles are annotated with: female fusome; chorion; female germline cyst; oocyte nucleus; germarium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 384 amino acids

    Gene Ontology:
    Cellular Component: perinuclear region of cytoplasm [IDA]
    Biological Process: ovarian fusome organization [IMP]
    germarium-derived female germ-line cyst formation [IMP]
    oogenesis [IMP]
    karyosome formation [IMP]
    dorsal/ventral pattern formation [IMP]
    Molecular Function: molecular_function [ND]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNSNYTILNI RAHSWAEKDN LVFPTITKPV SNGWFAWSPI GQFEPNSQKV PYVVVPPSIK  60
   61 FPISLRYKDS PPKLEKKPNI FLDNMLQYIE SSSYMYVMVR NNQQAQLNAN IVCTSEVLEL 120
  121 MMCAPYEKKT GWSLGVTRYR NTMYICRIDV EQPDPIDQDN LKRAMQEFWL RNLRTHCVFE 180
  181 NGIKMHQHNQ SSEEHLRFHG VFSFDLNGNR VLFDSPVLAE MPSTTLNGSA LSWVDLQIRP 240
  241 MFMSRLDWPE HNRTEALKWW VKCFLLGIES LYIARRDENA HVHNIEKTLV RDLWKSCEKD 300
  301 WSPTVCANFM IYLLNCISQV MAPIDCPSTV YLFQFDASQG TVSYKGLRGR NQYTFVSDWF 360
  361 RMMLDDHTND MCKTPNLQTM SSIV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..179] MSA 3.071954 View MSA. No confident structure predictions are available.
    2 View Details [180..384] MSA 2.071989 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle