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Protein Overview: CG8234-PA

General Information:
Name(s) found: CG8234-PA / FBpp0087180 [FlyBase]
Description(s) found:
Found 20 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG8234 (CG8234, FBgn0033644). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7563465..7565519. It has the cytological map location 48B8-48C1. Based on sequence similarity, it is predicted to have molecular function</span>: glucose transmembrane transporter activity; fructose transmembrane transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 488 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    Molecular Function: fructose transmembrane transporter activity [ISS]
    glucose transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILMRADTH VSFSVPADGL KANFTFSQVL AALSVSLCSL VVGFVSAYTS PALVSMTDRT  60
   61 ITSFEVTKDA GSWVGGIMPL AALAGGITGG PLIEYLGRRS TILATAVPFI VSSLLIACAV 120
  121 NVIMILCGRF LTGFCVGIAS LSLPVYLGET LQPEVRGTLG LLPTALGNIG ILVCYVAGSF 180
  181 MNWSMLAFLG AALPVPFLIL MIIIPETPRW FVNRGQEERA RKALKWLRGK EADVEPELKE 240
  241 LMQSQADADR QATQNTCLEL FKRNNLKPLS ISLGLMFFQQ FSGINAVIFY TVQIFKDAGS 300
  301 TIDSNLSTII VGVVNFFATF MGIILIDRLG RKILLYVSDI AMIVTLSILG GFFYCKAHGP 360
  361 DVSHLGWLPL TCFVIYILGF SLGFGPIPWL MMGEILPAKI RGPAASVVTA FNWFCTFVVT 420
  421 KTFQDLTVAM GAHGAFWLFG AICIVGLFFV IIFVPETRGK SLEEIERKMM GRVPMSSVVN 480
  481 IKPFPFNM

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..488] PSI-BLAST 24.154902 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • binding
    		•  1.46605775041083 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • alcohol transmembrane transporter activity
    		•  0.924836669821548 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  0.812001619402678 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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