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Protein Overview: dgo-PA, dgo-PB

General Information:
Name(s) found: dgo-PB / FBpp0087345 [FlyBase]
dgo-PA / FBpp0087344 [FlyBase]
Description(s) found:
Found 32 descriptions.
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  • The gene diego is referred to in FlyBase by the symbol Dmel\dgo (CG12342, FBgn0086898). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6703531..6707378. It has the cytological map location 47C1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: establishment of planar polarity; establishment of imaginal disc-derived wing hair orientation; establishment of ommatidial polarity. 11 alleles are reported. The phenotypes of these alleles are annotated with: ommatidial precursor cluster; photoreceptor cell R4; ommatidium; photoreceptor cell R3; wing hair. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene diego is referred to in FlyBase by the symbol Dmel\dgo (CG12342, FBgn0086898). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:6703531..6707378. It has the cytological map location 47C1. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: establishment of planar polarity; establishment of imaginal disc-derived wing hair orientation; establishment of ommatidial polarity. 11 alleles are reported. The phenotypes of these alleles are annotated with: ommatidial precursor cluster; photoreceptor cell R4; ommatidium; photoreceptor cell R3; wing hair. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 927 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [TAS]
    Biological Process: establishment of planar polarity [IMP][TAS]
    establishment of imaginal disc-derived wing hair orientation [IMP][TAS]
    establishment of ommatidial planar polarity [IMP][TAS]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHGSSRIPK QEALPNAISG PDSSNWTSLH EAVAAGDDRR VEGLLFSNAD RLARESVQGN  60
   61 TPLHEAASRG FSRCVKLICT PPTPPASSGV GKAAKGQKDK DKDKNKGRVK VAHQTIEALH 120
  121 NSALGIANNE GLSALHLAAQ NGHNQSSREL LLAGADPDVR NNYGDTPLHT ACRYGHAGVS 180
  181 RILLSALCDP NKTNLNGDTA LHITCAMGRR KLTRILLEAD ARLGIKNAQG DCPMHIAIRK 240
  241 NYREIIEILN TPKKIRNRKE KPKEGGSRSD KDRDRERDVV DKGINWSPYG CHYFPDPRAF 300
  301 PSPKLETLPK EPLKSGEQYF LDLAGHIHKG PVSVGNTCYC GPFFRHIENK LNCNRKSLKK 360
  361 YVHKTKERLG HKVQALAIKT NDQIEQLTRT MIEDRLRCES KRQHLSEFLR RGEPMRSTFD 420
  421 QQNKSSRIER TMSRCRSLEL LENNHEGGRL TNSRSVDVLE DQAVEAIVHR SAEVQVDSDS 480
  481 DDDSNEARDE EEAEVGDKDQ VQEEAEPEEH SKLDELKLDF LKVSERLGVL LEKTTLIMER 540
  541 DSEQESKRQL SSLSPPYNPH PRAESAQLRE DKESVNSPNF DEYANVIRRY PNSSETSNPS 600
  601 QNSNSWDWEA SPTGSNPHPD YNKYYQRIGR GENMLNSVIK ALRKDASFAD LGKEETAVNE 660
  661 TAEGMGGDKL LYKEQASEAA GISNLMKRQP LCLEDNYPVM SNLFYSNPIM EYAEETEVRQ 720
  721 NGNESMSKVE IRNSEIKCLK KPNAGQVRDM VAQLQNTIDS NRQDSQTAHV IAARSHSRLN 780
  781 NNFHHLEGTS SNPSPTYSIP HRSSAQFGLP ERHIPKDAYF HELPHRPPIP QTPQRRLHSG 840
  841 YVPNASLYRS EDLYVGRIPH PNAPPRQVDY VDAVAYRPLQ SPTFQAIVPP HVNQRPRNWP 900
  901 HPNLPSNEID LDELSAVGLY NNVSSLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..92] PSI-BLAST 56.0 Crystal structure of ribonuclease
    2 View Details [93..560] PSI-BLAST 103.0 Ankyrin-R
    3 View Details [561..689] MSA 1.169985 View MSA. No confident structure predictions are available.
    4 View Details [690..927] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  1.98134935593201 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.93050618316228 bayes_pls_golite062009
  • protein binding
    		•  1.54890102798695 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  1.29094941611102 bayes_pls_golite062009
  • structural molecule activity
    		•  0.808967137205604 bayes_pls_golite062009
  • enzyme binding
    		•  0.60140077251711 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
    		•  0.592443052058176 bayes_pls_golite062009
  • small conjugating protein ligase activity
    		•  0.529085233093928 bayes_pls_golite062009
  • actin binding
    		•  0.168912685840912 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle