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Protein Overview: FBpp0308510, CG1...

General Information:
Name(s) found: FBpp0308510 [FlyBase]
CG12130-PA / FBpp0087473 [FlyBase]
Description(s) found:
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  • gi|74867287|sp|Q9V5E1.1|PAL1_DROME RecName: Full=Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1; AltName: Full=Peptidylamidoglycolate lyase 1; AltName: Full=dPAL1; Flags: Precursor [NCBI NR]
  • gi|7303823|gb|AAF58870.1| CG12130, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|24652264|ref|NP_610537.2| CG12130, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|211938565|gb|ACJ13179.1| FI05303p [Drosophila melanogaster] [NCBI NR]
  • Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1 OS=Drosophila melanogaster GN=Pal1 PE=1 SV=1 [Swiss-Prot]
  • type=protein; loc=2R:join(5847706..5847807,5848031..5848208,5848268..5848508,5849068..5849567,5849731..5850165,5850703..5850872); ID=FBpp0308510; name=Pal1-PD; parent=FBgn0033466,FBtr0339423; dbxref=FlyBase:FBpp0308510,FlyBase_Annotation_IDs:CG12130-PD; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG12130 (CG12130, FBgn0033466). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:5847054..5851358. It has the cytological map location 46C7. There is experimental evidence that it has the molecular function</span>: peptidylamidoglycolate lyase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: oxidation reduction; peptide metabolic process. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • >CG12130-PA translation from_gene[CG12130 CG12130 FBgn0033466] seq_release:3 mol_weight=59642 cds_boundaries:(2R:5,020,834..5,023,997[+]) aa_length:541 transcript_info:[CG12130-RA seq_release:3] gene_info:[gene symbol:CG12130 FBgn0033466 gene_boundarie [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V5E1) CG12130 protein [DrosMelano7227.FASTAC.txt]
  • (AE003831) CG12130 gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG12130-PA [Drosophila melanogaster]gi|24652264|ref|NP_610537.2| CG12130-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(5847706..5847807,5848031..5848208,5848268..5848508,5849068..5849567,5849731..5850165,5850703..5850872); ID=FBpp0087473; name=CG12130-PA; parent=FBgn0033466,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473 [fly-100309-contam.fasta]
  • CG12130-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Peptidyl-alpha-hydroxyglycine alpha-amidating lyase 1 precursor (Peptidylamidoglycolate lyase 1) (dPAL1) [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(5847706..5847807,5848031..5848208,5848268..5848508,5849068..5849567,5849731..5850165,5850703..5850872); ID=FBpp0087473; name=CG12130-PA; parent=FBgn0033466,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,REFSEQ:NP_610537,GB_protein:AAF58870; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(5847706..5847807,5848031..5848208,5848268..5848508,5849068..5849567,5849731..5850165,5850703..5850872); ID=FBpp0087473; name=CG12130-PA; parent=FBgn0033466,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,GB_protein:AAF58870,REFSEQ:NP_610537; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • FI05303p OS=Drosophila melanogaster GN=CG12130-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(5847706..5847807,5848031..5848208,5848268..5848508,5849068..5849567,5849731..5850165,5850703..5850872); ID=FBpp0087473; name=Pal1-PA; parent=FBgn0033466,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,GB_protein:AAF58870,REFSEQ:NP_610537,FlyMine:FBpp0087473,modMine:FBpp0087473; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0308510; name=Pal1-PD; parent=FBgn0033466,FBtr0339423; dbxref=GB_protein:ACL83084,REFSEQ:NP_001137630,FlyBase:FBpp0308510,FlyBase_Annotation_IDs:CG12130-PD; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0087473; name=Pal1-PA; parent=FBgn0033466,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,GB_protein:AAF58870,REFSEQ:NP_610537,FlyMine:FBpp0087473,modMine:FBpp0087473; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0308510; name=Pal1-PD; parent=FBgn0033466,FBtr0339423; dbxref=GB_protein:ACL83084,REFSEQ:NP_001137630,FlyBase:FBpp0308510,FlyBase_Annotation_IDs:CG12130-PD; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0087473; name=Pal1-PA; parent=FBgn0033466,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,GB_protein:AAF58870,REFSEQ:NP_610537,FlyMine:FBpp0087473,modMine:FBpp0087473; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9V5E1, FI05303p OS=Drosophila melanogaster GN=Pal1 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0087473 type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0087473; name=Pal1-PA; parent=FBgn0283510,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,GB_protein:AAF58870,REFSEQ:NP_610537,FlyMine:FBpp0087473,modMine:FBpp0087473; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0308510 type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0308510; name=Pal1-PD; parent=FBgn0283510,FBtr0339423; dbxref=GB_protein:ACL83084,REFSEQ:NP_001137630,FlyBase:FBpp0308510,FlyBase_Annotation_IDs:CG12130-PD; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0087473; name=Pal1-PA; parent=FBgn0283510,FBtr0088385; dbxref=FlyBase_Annotation_IDs:CG12130-PA,FlyBase:FBpp0087473,GB_protein:AAF58870,REFSEQ:NP_610537,UniProt/Swiss-Prot:Q9V5E1,FlyMine:FBpp0087473,modMine:FBpp0087473; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2R:join(9960201..9960302,9960526..9960703,9960763..9961003,9961563..9962062,9962226..9962660,9963198..9963367); ID=FBpp0308510; name=Pal1-PD; parent=FBgn0283510,FBtr0339423; dbxref=GB_protein:ACL83084,REFSEQ:NP_001137630,FlyBase:FBpp0308510,FlyBase_Annotation_IDs:CG12130-PD,UniProt/Swiss-Prot:Q9V5E1; MD5=eb96e967984d2e0256b5b0935dae8a00; length=541; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 541 amino acids

    Gene Ontology:
    Cellular Component: membrane [IEA]
    neuronal cell body [IDA]
    Biological Process: peptide metabolic process [IEA]
    oxidation reduction [IEA]
    Molecular Function: peptidylglycine monooxygenase activity [ISS]
    copper ion binding [IEA]
    peptidylamidoglycolate lyase activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKSTDSAKCL GSKSLAICCL LLHLLLCIRP AVSQTQSPQR YLHNVDSNSN NNERLHQILK  60
   61 GSGAGSGATQ LNWPQPPKQT VPNVKTELAK LNNTYVYQNA WPANNVKLGA VTAVSFDKAG 120
  121 NVVIFHRVNR VWGQTTFDNR NQYQEKYRGP IRESTILALE PATGKVQYDW GKNFFYMPHG 180
  181 LTVDPEDNVW LTDVAMHQVF KFPPRGGDGK PALTLGDAFQ PGSGRKFCKP TSVAVLDNGD 240
  241 FFVADGYCNA RILKYSRKGE LILFWGQNTF SGISYDVAPQ NFFAIPHALT LVPELQLLCA 300
  301 ADRENGRVQC FLSSNGTFHS QYHNQLIGDR LFSMAYTPAA GGQLVIVNGP TAELGIHPEH 360
  361 YNEVHGFVLS MRSKQLVSKF GPNNLQFQNP HDVAVTADGN EIYVAELNPM RIHKFVHRSL 420
  421 AKPMSLSASK DSRDSAISQA VGGDQVPAVA VHHPSGKAIL VASLMLLFAG STFALALIFA 480
  481 RRRKRGCLPF GARGRRHAWE KSDGFKLGGL LDRDRNGFEK LDQQASDEEQ ETKTLASAQY 540
  541 A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..421] PSI-BLAST 13.30103 Actin interacting protein 1
    2 View Details [422..541] PSI-BLAST 26.69897 Surface layer protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  0.63587619876943 bayes_pls_golite062009
  • protein binding
    		•  0.280404893874779 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
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