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Protein Overview: CG8690-PA

General Information:
Name(s) found: CG8690-PA / FBpp0087831 [FlyBase]
Description(s) found:
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  • gi|24586599|ref|NP_610384.1| CG8690 [Drosophila melanogaster] [NCBI NR]
  • gi|21627689|gb|AAF59083.2| CG8690 [Drosophila melanogaster] [NCBI NR]
  • This gene is referred to in FlyBase by the symbol Dmel\CG8690 (CG8690, FBgn0033297). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:4359470..4361448. It has the cytological map location 44D1. Based on sequence similarity, it is predicted to have molecular function</span>: alpha-glucosidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: carbohydrate metabolic process. One allele is reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG8690-PA translation from_gene[CG8690 CG8690 FBgn0033297] seq_release:3 mol_weight=67024 cds_boundaries:(2R:3,532,730..3,534,687[+]) aa_length:588 transcript_info:[CG8690-RA seq_release:3] gene_info:[gene symbol:CG8690 FBgn0033297 gene_boundaries:(2R [hmr_yeast5_DM3-1_pombe.fasta]
  • (Q9V4U2) CG8690 protein [DrosMelano7227.FASTAC.txt]
  • CG8690-PA [Drosophila melanogaster]gi|24586599|ref|NP_610384.1| CG8690-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2R:join(4359488..4360588,4360646..4361100,4361161..4361304,4361382..4361448); ID=FBpp0087831; name=CG8690-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610 [fly-100309-contam.fasta]
  • CG8690-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2R:join(4359488..4360588,4360646..4361100,4361161..4361304,4361382..4361448); ID=FBpp0087831; name=CG8690-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2R:join(4359488..4360588,4360646..4361100,4361161..4361304,4361382..4361448); ID=FBpp0087831; name=CG8690-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • CG8690 OS=Drosophila melanogaster GN=Mal-A8 PE=4 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2R:join(4359488..4360588,4360646..4361100,4361161..4361304,4361382..4361448); ID=FBpp0087831; name=Mal-A8-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083,FlyMine:FBpp0087831,modMine:FBpp0087831; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2R:join(8471983..8473083,8473141..8473595,8473656..8473799,8473877..8473943); ID=FBpp0087831; name=Mal-A8-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083,FlyMine:FBpp0087831,modMine:FBpp0087831; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2R:join(8471983..8473083,8473141..8473595,8473656..8473799,8473877..8473943); ID=FBpp0087831; name=Mal-A8-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083,FlyMine:FBpp0087831,modMine:FBpp0087831; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Maltase A8 OS=Drosophila melanogaster GN=Mal-A8 PE=4 SV=1 [DROME.fasta.20160308]
  • FBpp0087831 type=protein; loc=2R:join(8471983..8473083,8473141..8473595,8473656..8473799,8473877..8473943); ID=FBpp0087831; name=Mal-A8-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083,FlyMine:FBpp0087831,modMine:FBpp0087831; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2R:join(8471983..8473083,8473141..8473595,8473656..8473799,8473877..8473943); ID=FBpp0087831; name=Mal-A8-PA; parent=FBgn0033297,FBtr0088752; dbxref=FlyBase:FBpp0087831,FlyBase_Annotation_IDs:CG8690-PA,GB_protein:AAF59083.2,REFSEQ:NP_610384,GB_protein:AAF59083,UniProt/TrEMBL:A1Z7F3,FlyMine:FBpp0087831,modMine:FBpp0087831; MD5=72367693fae377f6f557b63dd23a36dc; length=588; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 588 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: carbohydrate metabolic process [IEA]
    Molecular Function: alpha-glucosidase activity [ISS]
    cation binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MELLSLLTLL LLAIASNEAC QVQSSSSETT KDWWQTAQFY QIYPRSFKDS DGDGIGDLNG  60
   61 ITSKLEYLKD LGVTAAWLSP IFKSPMVDFG YDISDFFDIQ PEYGTLEDFR TLIKRAKELD 120
  121 LKIVLDFVPN HSSNESEWFL KSVKREKGYE DYYVWHDGKV NSTTGKREPP TNWLQYFRGS 180
  181 AWEWNEVRQQ YYLHQFAVQQ PDLNYRNPLV VEQMKRVLRY WLNEGVSGFR CDALPPLFEV 240
  241 VPDSDGQFPD EVVSGATEDK EDRDYLTTTY IENQPETIDM VYQWRTVLDD HKRIFGGNSS 300
  301 VLLIETYSPA WFTMQFYGNR STEGAHLPFN FNLITVMEQS GLSASNVQEA IDLWLKNMPA 360
  361 GRTPNWVLGN HDKRRAASRY GKENIDGMNM LVMILPGVSV TYQGEEIGMT DGEISWEDTV 420
  421 DPWGCNSNPN IYEQYTRDPE RTPFQWTGGT NAGFTNGSST WLPLAADYAT INVEKELSDD 480
  481 HSHLKIYKAL VALRKSSKTL QNGSTKYQAL SEDIFVVQRS LTKSATIVLV INFGSVAKTV 540
  541 DLSQFDKSRT ESLQLLIRSI DSTKKEGTRY DPKALSLDPS EALVLTTE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..588] PSI-BLAST 125.0 CRYSTAL STRUCTURE OF B. CEREUS OLIGO-1,6-GLUCOSIDASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • hydrolase activity, hydrolyzing O-glycosyl compounds
    		•  4.11319792356479 bayes_pls_golite062009
  • hydrolase activity, acting on glycosyl bonds
    		•  3.92012282533754 bayes_pls_golite062009
  • hydrolase activity
    		•  3.21770945631891 bayes_pls_golite062009
  • chitinase activity
    		•  2.45357334610104 bayes_pls_golite062009
  • structural molecule activity
    		•  2.28030619331997 bayes_pls_golite062009
  • trehalase activity
    		•  2.11042620996316 bayes_pls_golite062009
  • alpha-amylase activity
    		•  2.09193270404736 bayes_pls_golite062009
  • amylase activity
    		•  2.03484942782894 bayes_pls_golite062009
  • catalytic activity
    		•  1.85569074294201 bayes_pls_golite062009
  • alpha-glucosidase activity
    		•  0.96543619590958 bayes_pls_golite062009
  • glucosidase activity
    		•  0.766503513427695 bayes_pls_golite062009
  • hexosaminidase activity
    		•  0.763360027922833 bayes_pls_golite062009
  • binding
    		•  0.63693798355947 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.4998423581103 bayes_pls_golite062009
  • maltase activity
    		•  0.442635030512661 bayes_pls_golite062009
  • sugar binding
    		•  0.36459095255871 bayes_pls_golite062009
  • transferase activity, transferring hexosyl groups
    		•  0.266938437560648 bayes_pls_golite062009
  • beta-N-acetylhexosaminidase activity
    		•  0.263065978664289 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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