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Protein Overview: sut2-PA

General Information:
Name(s) found: sut2-PA / FBpp0087856 [FlyBase]
Description(s) found:
Found 22 descriptions.
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  • The gene sugar transporter 2 is referred to in FlyBase by the symbol Dmel\sut2 (CG17975, FBgn0028562). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3974921..3976802. It has the cytological map location 44A4. Based on sequence similarity, it is predicted to have molecular function</span>: glucose transmembrane transporter activity; sugar:hydrogen symporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: transmembrane transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 491 amino acids

    Gene Ontology:
    Cellular Component: integral to membrane [IEA]
    Biological Process: transmembrane transport [IEA]
    Molecular Function: sugar:hydrogen symporter activity [ISS]
    glucose transmembrane transporter activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVVMHVTPP KVNGWTPLLM LICLTVTLGT TIPVGYFFGV LNAPAEIIKK WCQDILANEY  60
   61 DTIVTAGQLD ILWTSIVSIY LIGGICGSCF SAVLCDKYGR KGCLVISSVL FVVSGILFTW 120
  121 CRAAKSLEML MTGRFLGGIA SALIFTAQPM YLLESAPSEL SGSVGVFTCI GVTGGILLAQ 180
  181 VATLSHLLGS ERLWPYALSF YSLLVMASLV LLWWFPESPR WLYLHKRDSA ASEKALLRLR 240
  241 GRNTEEEVHQ ELLEMKATLE AKSSSEVSSL CSVLRNSELW LPLLLVCSFQ ATQQLSGINA 300
  301 IFFYSLSILT NAGFSDGAAT WLNLGIGSFN LCTSLLGPLL IRRFPRRPLM MISCSMCALA 360
  361 LLAMSLGLFF LERSESTVLT YFCAAFILTF ILGFQLGLGP IAYFIGSELL EDSPRPVAMS 420
  421 MGSLFSWIGN FLVGMCFPLL QSVWSSFAFI PCMCVCIYCL LLTWRYLPET RGREPKDVKL 480
  481 LMSQGLSSKL N

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..491] PSI-BLAST 22.045757 Crystal Structure of the Glycerol-3-Phosphate Transporter from E.Coli

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • alcohol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • polyol transmembrane transporter activity
    		•  6.7545566917184 bayes_pls_golite062009
  • glycerol transmembrane transporter activity
    		•  6.54968363274124 bayes_pls_golite062009
  • glycerol-3-phosphate transmembrane transporter activity
    		•  5.40344495119017 bayes_pls_golite062009
  • transporter activity
    		•  4.09176719149278 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  3.59744164024479 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  3.5865018981083 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  3.54194478414824 bayes_pls_golite062009
  • hexose phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • glucose-6-phosphate transmembrane transporter activity
    		•  3.29248638217469 bayes_pls_golite062009
  • sugar:hydrogen symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • cation:sugar symporter activity
    		•  2.99050613058546 bayes_pls_golite062009
  • carbohydrate transmembrane transporter activity
    		•  2.62141276633776 bayes_pls_golite062009
  • sugar transmembrane transporter activity
    		•  2.47557586092261 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.21266150105753 bayes_pls_golite062009
  • solute:hydrogen symporter activity
    		•  2.10485633822652 bayes_pls_golite062009
  • binding
    		•  1.89539096965643 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  1.79369588808394 bayes_pls_golite062009
  • monosaccharide transmembrane transporter activity
    		•  1.6904339767429 bayes_pls_golite062009
  • active transmembrane transporter activity
    		•  1.59419818573076 bayes_pls_golite062009
  • secondary active transmembrane transporter activity
    		•  1.22264637452409 bayes_pls_golite062009
  • symporter activity
    		•  0.74591237387473 bayes_pls_golite062009
  • solute:cation symporter activity
    		•  0.74591237387473 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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