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Protein Overview: nito-PA, FBpp030...

General Information:
Name(s) found: FBpp0308267 [FlyBase]
nito-PB / FBpp0087934 [FlyBase]
nito-PA / FBpp0087933 [FlyBase]
Description(s) found:
Found 40 descriptions.
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  • type=protein; loc=2R:join(3850348..3850898,3850957..3852787); ID=FBpp0308267; name=nito-PC; parent=FBgn0027548,FBtr0339122; dbxref=FlyBase:FBpp0308267,FlyBase_Annotation_IDs:CG2910-PC; MD5=ccf6f17823c4dfc00317c92a2a234e07; length=793; release=r5.56; species=Dmel; [FlyBase]
  • The gene spenito is referred to in FlyBase by the symbol Dmel\nito (CG2910, FBgn0027548). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3849991..3857320. It has the cytological map location 43F8-43F9. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of transcription. 7 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye disc; eye; eye photoreceptor cell; ommatidium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • The gene spenito is referred to in FlyBase by the symbol Dmel\nito (CG2910, FBgn0027548). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3849991..3857320. It has the cytological map location 43F8-43F9. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: regulation of transcription. 7 alleles are reported. The phenotypes of these alleles are annotated with: rhabdomere; eye disc; eye; eye photoreceptor cell; ommatidium. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 793 amino acids

    Gene Ontology:
    Cellular Component: precatalytic spliceosome [IDA]
    Biological Process: regulation of transcription [IEA]
    nuclear mRNA splicing, via spliceosome [IC]
    Molecular Function: nucleotide binding [IEA]
    nucleic acid binding [IEA]
    mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSHRDGAGA DRITIKIHNM KRSASRSPGP ASRSSLSRNS RSMGRGYDNG SGVPGDSPER  60
   61 LSPERMRRRL DRSPSRYGSP HREPYMRGPP PAERPAGYKV LCVSALPPKA PDDFIEETLY 120
  121 REYKKFGDFS VRLAHDLDER VAYVCFRTPE DAREAKHHKP RLIIYDKMAI VEPVYKSTTR 180
  181 PEYRPRGHSM SPPDYERYHY SRSPMGQGVP LDHRRPPIDP YDRYGPPHMH PHAVHPRDYR 240
  241 PLHHDYPHPP RGPPLHRGGH PHHLHGHAPP HQYAPMRPLA PRPHAPYEKP ESKKDKFPNY 300
  301 LHHVQPEDDP LSTRTLFAGN LEVTIADDEL RRIFGKYGVV DDIDIKRPPP GTGNAFAFVR 360
  361 YQNLDMAHRA KIELSGQYIG KFQCKIGYGK VTPATRMWIG GLGAWTSVTQ LEREFDRFGA 420
  421 IKKIEYQKGE PYAYIQYETV EAATAAVKEM RGFPLGGPER RLRTDFAELP GATPAAPFKS 480
  481 SKPPYDESAL EYRRPEYDPY YEESAAYAPR GGYSPYPPRG GYRGRGGYRG RGRGMYHYHN 540
  541 DVHRPPHPGS LAGSSSSVPP PGGVEDEWRR PPGESYDRGA RSSSREPGVE RSRSRSPLKR 600
  601 ARSPGSDSDT STRRNDALAS ASTVPDVARK CSTVWTGALI LKSSLFPAKF HLTDGDTDIV 660
  661 ESLMRDEEGK HNLRITQRLR LDPPKLDDVQ KRIASSSSHA IFMGLAGSTN DTNCDDASVQ 720
  721 TRPLRNLVSY LKQKEAAGVI SLLNKETEAT GVLYAFPPCD FSTELLKRTC HSLTEEGLKE 780
  781 DHLVIVVVRG GTA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..95] deduced N/A No confident structure predictions are available.
    2 View Details [96..196] PSI-BLAST 7.522879 Solution structure of the RNA recognition motif from hypothetical RNA binding protein BC052180
    3 View Details [197..291] deduced N/A No confident structure predictions are available.
    4 View Details [292..457] PSI-BLAST 28.0 No description for 2cjkA was found.
    5 View Details [458..609] PSI-BLAST 3.154902 No description for 1y0fB was found.
    6 View Details [610..793] PSI-BLAST 57.69897 Crystal structure of the SPOC domain of the human transcriptional corepressor, SHARP.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  0.950788308762215 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.29562225149076 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle