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Protein Overview: blow-PA, FBpp0301751

General Information:
Name(s) found: FBpp0301751 [FlyBase]
blow-PA / FBpp0088026 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • type=protein; loc=2R:complement(3468295..3469859,3470119..3470433,3472561..3472615); ID=FBpp0301751; name=blow-PD; parent=FBgn0004133,FBtr0310050; dbxref=FlyBase:FBpp0301751,FlyBase_Annotation_IDs:CG1363-PD,REFSEQ:NP_001163073,GB_protein:ACZ94352; MD5=3c3333842a1d4746444b7c7d01304a4d; length=644; release=r5.56; species=Dmel; [FlyBase]
  • The gene blown fuse is referred to in FlyBase by the symbol Dmel\blow (CG1363, FBgn0004133). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3467993..3474581. It has the cytological map location 43E1-43E3. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process</span>: myoblast fusion; mesoderm development. 8 alleles are reported. The phenotypes of these alleles are annotated with: myoblast; embryonic muscle system; embryonic myoblast; somatic muscle primordium; abdominal dorsal acute muscle 1; embryonic/larval somatic muscle. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 644 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA][NAS]
    Biological Process: skeletal muscle tissue development [TAS]
    myoblast fusion [IMP][TAS]
    mesoderm development [IEP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPKPTTTKL AEIEQFLLDV RAHFRASLET SEYENTSNLF HVTAAEQTAA LLARCEILLA  60
   61 AASSASGSGS GLELGSGLGC ADEQAAANHR SSLVDCVDSK VGAETGPSGY LEMLASPSPS 120
  121 KSSLSASREY IDLGSSGSLD RCSVNQPVPA AKDKEPHQQL YEICQGQGAG QDEDEAQQAI 180
  181 TFTHEVFIDC PYADLPAGHL SLQRSTKYGQ LQRIVPKRLF FDQTRKCYCG ILNDWMLCYA 240
  241 DGPTACRPSS TLYLKSSSIE IEHFGEGKRR DICFQITTDD PNKKFVYQAN NEVDAKEWIH 300
  301 AIEAAIRGDA GAHSALKTPP PRKLPTPPVQ KKSTYTAADI IYEEPSPVYG LIDSSSMVLP 360
  361 KLPEKSNSPS ALARRFEYDV PKCPAQPLQD TSSRVASVSG ELESLGLLNE GDIKVQPQPS 420
  421 SLHGSISLDF QARVKTVHSE LSTQLSAAGP SPDRLKKAAK KSYSNGSEPE MLSPLTSPVQ 480
  481 TPTKDQKKQR KSTTSPQSSP VSKDCDKLAR NWFLSRLNKS TGLKATNTGS ASPTNAKCKQ 540
  541 SEKENLLTEA ELGEGYDASP GDRYHGLPGS PPTSPCLKAE AKSKVNMIIN QFESSGHLST 600
  601 MFSVEALAAN ALASLTSFCE SDGCNNYEPI MPLATTPSSF LKKV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..120] deduced N/A No confident structure predictions are available.
    2 View Details [121..316] PSI-BLAST 39.69897 Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
    3 View Details [317..360] PSI-BLAST 9.0 No description for 2j59M was found.
    4 View Details [361..566] MSA 10.214995 View MSA. No confident structure predictions are available.
    5 View Details [567..644] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • binding
    		•  2.50303824442522 bayes_pls_golite062009
  • protein binding
    		•  2.1446140694885 bayes_pls_golite062009
  • phospholipid binding
    		•  0.1447983722611 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.98

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle