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View Structure Prediction Details

Protein: blow-PA, FBpp0301751
Organism: Drosophila melanogaster
Length: 644 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for blow-PA, FBpp0301751.

Description E-value Query
Range
Subject
Range
gi|1816590 - gi|1816590|gb|AAB42078.1| blown fuse protein [Drosophila melanogaster]
644.0 [0..1] [644..1]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPKPTTTKL AEIEQFLLDV RAHFRASLET SEYENTSNLF HVTAAEQTAA LLARCEILLA  60
   61 AASSASGSGS GLELGSGLGC ADEQAAANHR SSLVDCVDSK VGAETGPSGY LEMLASPSPS 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [121-316]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSSLSASREY IDLGSSGSLD RCSVNQPVPA AKDKEPHQQL YEICQGQGAG QDEDEAQQAI  60
   61 TFTHEVFIDC PYADLPAGHL SLQRSTKYGQ LQRIVPKRLF FDQTRKCYCG ILNDWMLCYA 120
  121 DGPTACRPSS TLYLKSSSIE IEHFGEGKRR DICFQITTDD PNKKFVYQAN NEVDAKEWIH 180
  181 AIEAAIRGDA GAHSAL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 39.69897
Match: 1u5eA
Description: Crystal Structure of a N-terminal Fragment of SKAP-Hom Containing Both the Helical Dimerization Domain and the PH Domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 2.50303824442522 bayes_pls_golite062009
protein binding 2.1446140694885 bayes_pls_golite062009
phospholipid binding 0.1447983722611 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [317-360]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KTPPPRKLPT PPVQKKSTYT AADIIYEEPS PVYGLIDSSS MVLP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.0
Match: 2j59M
Description: No description for 2j59M was found.

Predicted Domain #4
Region A:
Residues: [361-566]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLPEKSNSPS ALARRFEYDV PKCPAQPLQD TSSRVASVSG ELESLGLLNE GDIKVQPQPS  60
   61 SLHGSISLDF QARVKTVHSE LSTQLSAAGP SPDRLKKAAK KSYSNGSEPE MLSPLTSPVQ 120
  121 TPTKDQKKQR KSTTSPQSSP VSKDCDKLAR NWFLSRLNKS TGLKATNTGS ASPTNAKCKQ 180
  181 SEKENLLTEA ELGEGYDASP GDRYHG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [567-644]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LPGSPPTSPC LKAEAKSKVN MIINQFESSG HLSTMFSVEA LAANALASLT SFCESDGCNN  60
   61 YEPIMPLATT PSSFLKKV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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