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Protein Overview: so-PA

General Information:
Name(s) found: so-PA / FBpp0089177 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • The gene sine oculis is referred to in FlyBase by the symbol Dmel\so (CG11121, FBgn0003460). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3306537..3322377. It has the cytological map location 43B3-43C1. There is experimental evidence that it has the molecular function</span>: protein binding; sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process</span>: entrainment of circadian clock; ring gland development; glial cell migration; circadian rhythm; optic lobe placode formation; compound eye morphogenesis; spermatogenesis; Bolwig's organ morphogenesis. 52 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: nervous system; adult segment; peripheral nervous system; multi-cell-component structure; external compound sense organ; adult brain; organ system; embryonic nervous system; endocrine system; larval head segment. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 416 amino acids

    Gene Ontology:
    Cellular Component: nucleus [ISS][NAS]
    Biological Process: entrainment of circadian clock [IMP]
    optic lobe placode formation [IMP]
    ring gland development [IMP]
    compound eye morphogenesis [IMP]
    Bolwig's organ morphogenesis [IMP]
    spermatogenesis [IMP]
    eye-antennal disc morphogenesis [TAS]
    regulation of transcription, DNA-dependent [IEA]
    circadian rhythm [IGI]
    regulation of transcription [IEA][ISS]
    compound eye development [NAS]
    glial cell migration [IMP]
    Molecular Function: transcription factor activity [IEA][TAS]
    protein binding [IPI]
    RNA polymerase II transcription factor activity [ISS]
    sequence-specific DNA binding [IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLQHPATDFY DLAAANAAAV LTARHTPPYS PTGLSGSVAL HNNNNNNSST SNNNNSTLDI  60
   61 MAHNGGGAGG GLHLNSSSNG GGGGGVVSGG GSGGRENLPS FGFTQEQVAC VCEVLQQAGN 120
  121 IERLGRFLWS LPQCDKLQLN ESVLKAKAVV AFHRGQYKEL YRLLEHHHFS AQNHAKLQAL 180
  181 WLKAHYVEAE KLRGRPLGAV GKYRVRRKFP LPRTIWDGEE TSYCFKEKSR SVLRDWYSHN 240
  241 PYPSPREKRD LAEATGLTTT QVSNWFKNRR QRDRAAEHKD GSTDKQHLDS SSDSEMEGSM 300
  301 LPSQSAQHQQ QQQQQQHSPG NSSGNNNGLH QQQLQHVAAE QGLQHHPHQP HPASNIANVA 360
  361 ATKSSGGGGG GGVSAAAAAQ MQMPPLTAAV AYSHLHSVMG AMPMTAMYDM GEYQHL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..93] deduced N/A No confident structure predictions are available.
    2 View Details [94..282] PSI-BLAST 27.69897 Oct-1 POU Homeodomain; Oct-1
    3 View Details [283..416] MSA 4.990996 View MSA. No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.79

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle