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Protein Overview: pwn-PA

General Information:
Name(s) found: pwn-PA / FBpp0088036 [FlyBase]
Description(s) found:
Found 13 descriptions.
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  • The gene pawn is referred to in FlyBase by the symbol Dmel\pwn (CG11101, FBgn0003174). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:3182813..3187907. It has the cytological map location 43A3. An electronic pipeline based on InterPro domains suggests that it has the molecular function</span>: calcium ion binding. There is experimental evidence that it is involved in the biological process</span>: phototransduction; bristle morphogenesis. 14 alleles are reported. The phenotypes of these alleles are annotated with: cornea; eye; retina; macrochaeta; chaeta. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1307 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: bristle morphogenesis [IMP]
    phototransduction [IMP]
    Molecular Function: calcium ion binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEWLLVGIE REPGQHESVS QISPKSSSHR SPDRQRIEST MADSVNGLAE GQSSPLDVND  60
   61 NETRAERVER SASPILHDRQ PIGPNDVHFP EDLEKDVSAG RYFHYNIKPT GTFDNQDEQP 120
  121 ERTHQGIRAG KTLSQGGSSS EQSFLGRGDL RPLVSGSPIR PSPSNTATSA TAASATQAPH 180
  181 SPRQNGNPDI QDIITGIVKL LNGNVNVHAN TQGIRRPSAS RINNRGPPRI SEAQNLPIDY 240
  241 EAQKPGTSMR PPPYPFDRPE RPFITGVPIP EQIVPVRPGF VSNRPPWYRN KPRPPIATSV 300
  301 GGNRRPLPQY KPLPAPPVQA PLQPQDPLDR KNEQEKEQNH QEQPQPTDDV VLPTDTTYDS 360
  361 EFSNEDANAQ YIEVSDQDTD ATGGEVEDEL QPPPPPPSTT NNPPTTPTNP SKKKHKPKPG 420
  421 SEKKKLPEES PQDEGFSTII ETSSVVHTVM GMSSTYVPMS MDSSESLGLD PSTEEVIFMT 480
  481 ANRTPTLEPS VTSSLGTSSS SNPASAIQPT SSKEHTKTTT TTTTTTSSST STTTSTTTPP 540
  541 STESVSPNSS NANTNATPPA PYHPRPGIVL DDPEFKPGGR PRPPVQRPPA QQTLPLPAVQ 600
  601 PTRQHLPPGY GEIFDVTLSA IQGPGPKGSG SQQTINIKPY GSYAAGGGQG DIIVSASGDD 660
  661 GFVSIDGKRT YINLFGDPTD PPAGATTPAT RLPQLPGSGS GSGSGSGTGS GGASTPGVGV 720
  721 SSGGGGGSGS SISPAAPANA VTQSSGGYVV PETEVVDLQG HSKPQGGAPT TNAGPTRPHY 780
  781 RQRPTQPPVR IDTCIVGDDS TCDQAQHERC KTDNGVSSCH CRPGYSRRKH REPCRRVISF 840
  841 HLGMRVDRIY EHRIVWDTKL MDKHSEPFGQ LSYESIRALD SAMSMTPYSD EFMEAKVNNI 900
  901 YRGDPNLGGS GVYVNMTIKL DESVETLRPN LRSDVQKHLL GVLHRRNNNI GNSVLYVSSP 960
  961 EGAVSALQDL DECQSPELND CHSGASCSNT WGSFRCACEA GLRDPWADQP ARSGRECQAC1020
 1021 ADSVCNNHGT CSYAEDGAQL CTCDSSHYGA QCEIDGEVLG VAIGASVAAI IIIVLTLVCL1080
 1081 IMWSRRWQRE QKNAMGSPVF GYMNTAPLKS AGLPQAGYQV TLEDRMRWAQ IADVMAQTNH1140
 1141 YGAEPIGPTR PSSAMFAYPN LGAMGMGTLG GMSLQSTMQM HPSATLAPPV PLPRRLGLGP1200
 1201 RSNGMRTLEN SSSSEEEDRA DLLGRNFQVP RPKSRSNGSI ANQSGIYYDV DYEPSGNGIG1260
 1261 NSSVDHLYGS QNQSVTHSSG HSHIPGPQGI PMSTYTSGRA PSSYYMK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..129] MSA 2.133995 View MSA. No confident structure predictions are available.
    2 View Details [130..345] deduced N/A No confident structure predictions are available.
    3 View Details [346..545] MSA 1.16698 View MSA. No confident structure predictions are available.
    4 View Details [546..745] deduced N/A No confident structure predictions are available.
    5 View Details [746..1202] PSI-BLAST 23.221849 Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
    6 View Details [1203..1307] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • protein binding
    		•  1.279921135544 bayes_pls_golite062009
  • binding
    		•  1.20290372802439 bayes_pls_golite062009
  • receptor binding
    		•  1.07208480206832 bayes_pls_golite062009
  • ErbB-2 class receptor binding
    		•  0.3648038027933 bayes_pls_golite062009
  • ErbB-3 class receptor binding
    		•  0.0872631558320198 bayes_pls_golite062009
  • growth factor activity
    		•  0.04792804882584 bayes_pls_golite062009
    6 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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