YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: Spn4-PB

General Information:
Name(s) found: Spn4-PB / FBpp0085523 [FlyBase]
Description(s) found:
Found 22 descriptions.
SHOW ALL
  • The gene Serine protease inhibitor 4 is referred to in FlyBase by the symbol Dmel\Spn4 (CG9453, FBgn0028985). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2763409..2766428. It has the cytological map location 42D6. There is experimental evidence that it has the molecular function</span>: serine-type endopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of peptide hormone processing; negative regulation of endopeptidase activity; negative regulation of protein maturation by peptide bond cleavage. 7 alleles are reported. The phenotype of these alleles is annotated with: cephalopharyngeal skeleton. It has 11 annotated transcripts and 11 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 424 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: negative regulation of protein maturation by peptide bond cleavage [IMP]
    negative regulation of peptide hormone processing [IMP]
    negative regulation of endopeptidase activity [IDA]
    Molecular Function: serine-type endopeptidase inhibitor activity [IDA][ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYRLVPCGC WLLPLLGLAL FPFPPVHTAD VTMADAAHQE FARRLALFSI NVYGKLSGQK  60
   61 PGENIVFSPF SIQTCAAMAR LGAENETATQ LDQGLGLASS DPEQIAHSFH QVLAAYQDSQ 120
  121 ILRIANKIFV MDGYQLRQEF DQLLSKQFLS AAQSVDFSKN VQAAATINNW VEQRTNHLIK 180
  181 DLVPADVLNS ESRLVLVNAI HFKGTWQHQF AKHLTRPDTF HLDGERTVQV PMMSLKERFR 240
  241 YADLPALDAM ALELPYKDSD LSMLIVLPNT KTGLPALEEK LRLTTLSQIT QSLYETKVAL 300
  301 KLPRFKAEFQ VELSEVFQKL GMSRMFSDQA EFGKMLQSPE PLKVSAIIHK AFIEVNEEGT 360
  361 EAAAATGMAV RRKRAIMSPE EPIEFFADHP FTYVLVHQKD LPLFWGSVVR LEENTFASSE 420
  421 HDEL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..424] PSI-BLAST 94.522879 No description for 2dutA was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle