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Protein Overview: SdhB-PA

General Information:
Name(s) found: SdhB-PA / FBpp0085489 [FlyBase]
Description(s) found:
Found 25 descriptions.
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  • The gene Succinate dehydrogenase B is referred to in FlyBase by the symbol Dmel\SdhB (CG3283, FBgn0014028). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2695116..2696678. It has the cytological map location 42D3-42D4. Based on sequence similarity, it is predicted to have molecular function</span>: succinate dehydrogenase (ubiquinone) activity. There is experimental evidence that it is involved in the biological process</span>: mitochondrial electron transport, succinate to ubiquinone. 6 alleles are reported. The phenotypes of these alleles are annotated with: mitochondrial crista; flight muscle; mitochondrion. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 297 amino acids

    Gene Ontology:
    Cellular Component: mitochondrial respiratory chain complex II [ISS][NAS]
    Biological Process: tricarboxylic acid cycle [ISS][NAS]
    mitochondrial electron transport, succinate to ubiquinone [IDA]
    Molecular Function: succinate dehydrogenase (ubiquinone) activity [ISS][NAS]
    electron carrier activity [IEA]
    iron-sulfur cluster binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLATEARQIL SRVGSLVARN QMRAISNGTA QLEQQAQPKE AQEPQIKKFE IYRWNPDNAG  60
   61 EKPYMQTYEV DLRECGPMVL DALIKIKNEM DPTLTFRRSC REGICGSCAM NIGGTNTLAC 120
  121 ISKIDINTSK SLKVYPLPHM YVVRDLVPDM NNFYEQYRNI QPWLQRKNEA GEKKGKAQYL 180
  181 QSVEDRSKLD GLYECILCAC CSTSCPSYWW NAEKYLGPAV LMQAYRWIID SRDENSAERL 240
  241 NKLKDPFSVY RCHTIMNCTR TCPKGLNPGR AIAEIKKLLS GLASKPAPKL ETAALHK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] PSI-BLAST 69.522879 Avian respiratory complex ii with oxaloacetate and ubiquinone


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle