YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Protein Overview: FBpp0305157, Eb1...

General Information:
Name(s) found: FBpp0305157 [FlyBase]
Eb1-PA / FBpp0085464 [FlyBase]
Eb1-PD / FBpp0085463 [FlyBase]
Eb1-PB / FBpp0085461 [FlyBase]
Description(s) found:
Found 55 descriptions.
SHOW ALL
  • type=protein; loc=2R:join(2640169..2640289,2640348..2640493,2641685..2641943,2642207..2642349,2642404..2642486,2642550..2642622,2642690..2642740); ID=FBpp0305157; name=Eb1-PG; parent=FBgn0027066,FBtr0332939; dbxref=REFSEQ:NP_001260734,GB_protein:AGB93267,FlyBase:FBpp0305157,FlyBase_Annotation_IDs:CG3265-PG; MD5=fc55b43a1f23b55cc9931a81f9d86d39; length=291; release=r5.56; species=Dmel; [FlyBase]
  • The gene Eb1 is referred to in FlyBase by the symbol Dmel\Eb1 (CG3265, FBgn0027066). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2636697..2643542. It has the cytological map location 42C8. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: locomotory behavior; pseudocleavage during syncytial blastoderm formation; mitotic spindle elongation; sensory organ development; chromosome segregation; flight behavior; spindle assembly. 24 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: cell cycle; adult segment; intracellular organelle part; peripheral nervous system; cell cycle process; protein complex; cytoskeletal part; nervous system; nuclear division; spindle; organ system; antennal segment; portion of tissue. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Eb1 is referred to in FlyBase by the symbol Dmel\Eb1 (CG3265, FBgn0027066). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2636697..2643542. It has the cytological map location 42C8. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: locomotory behavior; pseudocleavage during syncytial blastoderm formation; mitotic spindle elongation; sensory organ development; chromosome segregation; flight behavior; spindle assembly. 24 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: cell cycle; adult segment; intracellular organelle part; peripheral nervous system; cell cycle process; protein complex; cytoskeletal part; nervous system; nuclear division; spindle; organ system; antennal segment; portion of tissue. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • The gene Eb1 is referred to in FlyBase by the symbol Dmel\Eb1 (CG3265, FBgn0027066). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:2636697..2643542. It has the cytological map location 42C8. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: locomotory behavior; pseudocleavage during syncytial blastoderm formation; mitotic spindle elongation; sensory organ development; chromosome segregation; flight behavior; spindle assembly. 24 alleles are reported. The phenotypes of these alleles are annotated with 12 unique terms, many of which group under: cell cycle; adult segment; intracellular organelle part; peripheral nervous system; cell cycle process; protein complex; cytoskeletal part; nervous system; nuclear division; spindle; organ system; antennal segment; portion of tissue. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 291 amino acids

    Gene Ontology:
    Cellular Component: spindle microtubule [IDA]
    cytoplasm [IDA]
    cytoplasmic microtubule [IDA]
    microtubule associated complex [ISS][TAS]
    microtubule [IDA]
    Biological Process: mitotic spindle elongation [IDA][IMP]
    spindle assembly [IDA]
    locomotory behavior [IMP]
    establishment of mitotic spindle localization [NAS][TAS]
    mitotic spindle organization [TAS]
    flight behavior [IMP]
    chromosome segregation [IDA]
    sensory organ development [IMP]
    pseudocleavage during syncytial blastoderm formation [IMP]
    microtubule-based process [ISS][TAS]
    Molecular Function: protein binding [IPI]
    microtubule binding [IEA][ISS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAVNVYSTNV TSENLSRHDM LAWVNDCLQS QFSKIEELCT GAAYCQFMDM LFPNSVPVKR  60
   61 VKFRTNLEHE YIQNFKILQA GFKKMSVDKI IPIDKLVKGR FQDNFEFLQW FKKFFDANYD 120
  121 GRDYDASAVR EGAPMGFGSG AVKSLPGTAA SGVSSSYRRG PSATTRPAMT SAVKPTVSKV 180
  181 LPRTNNAAPA SRINACANST GTVKKNDVSN SVNNQQIEEM SNQVMDMRIN LEGLEKERDF 240
  241 YFSKLRDIEI LCQEADDAEA HPIIQKILDI LYATEDGFAP PDDAPPEDEE Y

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..210] PSI-BLAST 75.39794 Solution structure of the CH domain of human microtubule-associated protein RP/EB family member 3
    2 View Details [211..291] PSI-BLAST 26.0 Crystal structure of the EB1 C-terminal domain complexed with the CAP-Gly domain of p150Glued


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle