Protein Overview: FBpp0312101, E2f2-PA

General Information:
Name(s) found:	FBpp0312101 [FlyBase] E2f2-PA / FBpp0081029 [FlyBase]
Description(s) found: Found 32 descriptions. SHOW ALL	type=protein; loc=2L:complement(21154476..21154579,21154646..21154985,21155107..21155365,21155572..21155681,21155744..21156043); ID=FBpp0312101; name=E2f2-PB; parent=FBgn0024371,FBtr0346451; dbxref=FlyBase:FBpp0312101,FlyBase_Annotation_IDs:CG1071-PB; MD5=c9113a4426da0b518347bce13fbc8469; length=370; release=r5.56; species=Dmel; [FlyBase] The gene E2F transcription factor 2 is referred to in FlyBase by the symbol Dmel\E2f2 (CG1071, FBgn0024371). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:21154293..21156245. It has the cytological map location 39A5-39A6. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: oocyte anterior/posterior axis specification; negative regulation of transcription from RNA polymerase II promoter; negative regulation of DNA replication; DNA endoreduplication; oocyte dorsal/ventral axis specification. 25 alleles are reported. The phenotypes of these alleles are annotated with: chorion; eye; follicle cell; ommatidium. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	370 amino acids
Gene Ontology:
Cellular Component:	nucleus [ISS] transcription factor complex [IEA] Myb complex [IDA] chromatin [IDA]
Biological Process:	negative regulation of transcription from RNA polymerase II promoter [IMP] oogenesis [TAS] negative regulation of transcription [TAS] G1/S transition of mitotic cell cycle [TAS] endomitotic cell cycle [TAS] DNA endoreduplication [IGI][IMP] imaginal disc development [TAS] regulation of transcription, DNA-dependent [IEA] negative regulation of DNA replication [IMP] oocyte dorsal/ventral axis specification [IMP] regulation of transcription [ISS] oocyte anterior/posterior axis specification [IMP]
Molecular Function:	transcription factor activity [IEA] protein binding [NAS] RNA polymerase II transcription factor activity [ISS] transcription repressor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYKRKTASIV KRDSSAAGTT SSAMMMKVDS AETSVRSQSY ESTPVSMDTS PDPPTPIKSP  60
   61 SNSQSQSQPG QQRSVGSLVL LTQKFVDLVK ANEGSIDLKA ATKILDVQKR RIYDITNVLE 120
  121 GIGLIDKGRH CSLVRWRGGG FNNAKDQENY DLARSRTNHL KMLEDDLDRQ LEYAQRNLRY 180
  181 VMQDPSNRSY AYVTRDDLLD IFGDDSVFTI PNYDEEVDIK RNHYELAVSL DNGSAIDIRL 240
  241 VTNQGKSTTN PHDVDGFFDY HRLDTPSPST SSHSSEDGNA PACAGNVITD EHGYSCNPGM 300
  301 KDEMKLLENE LTAKIIFQNY LSGHSLRRFY PDDPNLENPP LLQLNPPQED FNFALKSDEG 360
  361 ICELFDVQCS

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.61

Protein Overview: FBpp0312101, E2f2-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: