Protein Overview: neb-PA

General Information:
Name(s) found:	neb-PA / FBpp0080864 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|7298657\|gb\|AAF53872.1\| nebbish [Drosophila melanogaster] [NCBI NR] gi\|17136640\|ref\|NP_476817.1\| nebbish [Drosophila melanogaster] [NCBI NR] gi\|162944908\|gb\|ABY20523.1\| LP17758p [Drosophila melanogaster] [NCBI NR] The gene nebbish is referred to in FlyBase by the symbol Dmel\neb (CG10718, FBgn0004374). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:20075756..20089706. It has the cytological map location 38B3-38B5. There is experimental evidence that it has the molecular function</span>: protein phosphatase 1 binding. There is experimental evidence that it is involved in the biological process</span>: mitotic chromosome condensation; mitotic cell cycle, embryonic; meiosis; ovarian follicle cell development; regulation of cell cycle. 50 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: peripheral nervous system; nervous system; organ system; external compound sense organ; female germline cyst; adult segment; neuron; nuclear part; spermatozoon; cytoplasmic part; adult external prothorax; multidendritic neuron. It has one annotated transcript and one annotated polypeptide. [FlyBase] >CG10718-PA translation from_gene[CG10718 neb FBgn0004374] seq_release:3 mol_weight=125223 cds_boundaries:(2L:20,053,934..20,067,646[+]) aa_length:1121 transcript_info:[CG10718-RA seq_release:3] gene_info:[gene symbol:neb FBgn0004374 gene_boundaries:(2 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VIP4) NEB protein [DrosMelano7227.FASTAC.txt] (AE003665) neb gene product [Drosophila melanogaster] [yeastflysequest.fasta] CG10718-PA [Drosophila melanogaster]gi\|17136640\|ref\|NP_476817.1\| CG10718-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872; MD5=06f [fly-100309-contam.fasta] CG10718-PA [Drosophila melanogaster] [nr-271106-contam.fasta] nebbish CG10718-PA [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] LP17758p OS=Drosophila melanogaster GN=neb PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872,FlyMine:FBpp0080864,modMine:FBpp0080864; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872,FlyMine:FBpp0080864,modMine:FBpp0080864; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872,FlyMine:FBpp0080864,modMine:FBpp0080864; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Kinesin-like protein OS=Drosophila melanogaster GN=neb PE=1 SV=1 [DROME.fasta.20160308] FBpp0080864 type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872,FlyMine:FBpp0080864,modMine:FBpp0080864; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:join(20075857..20077296,20087647..20089572); ID=FBpp0080864; name=neb-PA; parent=FBgn0004374,FBtr0081332; dbxref=FlyBase:FBpp0080864,FlyBase_Annotation_IDs:CG10718-PA,GB_protein:AAF53872.1,REFSEQ:NP_476817,GB_protein:AAF53872,UniProt/TrEMBL:Q9VIP4,FlyMine:FBpp0080864,modMine:FBpp0080864; MD5=06fa47e3e0984a200d8702e7e1d1997f; length=1121; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1121 amino acids
Gene Ontology:
Cellular Component:	kinesin complex [ISS]
Biological Process:	mitotic chromosome condensation [IMP] oogenesis [TAS] ovarian follicle cell development [IMP] chromosome segregation [TAS] regulation of cell cycle [IMP] microtubule-based movement [IEA][ISS] meiosis [IGI] mitotic cell cycle, embryonic [IMP]
Molecular Function:	ATP binding [IEA] microtubule motor activity [IEA][ISS] protein phosphatase 1 binding [IPI] chromatin binding [TAS] plus-end-directed microtubule motor activity [TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNKSTPVRQ RIQQFQTRGV HKSTPASEMR KKVLMTRAED REHRDRPEQL LNTAFSGSTP  60
   61 QPKPKPTALN ACYTPSSLYR NANSTPGRAK TPGTGKSSCS RTKERDSLME SCLSVSEESN 120
  121 MIVAVRVRPL NALECTRGQV TNVVQVHGNS NELTVQAGSS ADASAGVTHF FSYDQVYYSC 180
  181 DPERKNFACQ AKVFEGTARP LIDTAFEGYN ACLFAYGQTG SGKSYSMMGI EALDDAALDG 240
  241 GPPHDEAGII PRFCHELFRR IEAVKSQQQL QVEVEVSYFE IYNEKIHDLL SVQHAAAATG 300
  301 ESTPIQQQQQ QQRPALKVRE HPIFGPYVVD LSAHSVDSYS ALRNWLAVGN SQRATASTAM 360
  361 NDKSSRSHSI FNIVLNLTDL SSDDGLSSDT DSSTASSLRQ TRRSKISLVD LAGSERISVS 420
  421 GSNGERIREG VSINKSLLTL GKVIAALADS RKAIANGPLG SGTPSTFVPY RESVLTWLLR 480
  481 ENLGGNSKTV MLATISPASI HADETLATLR YACKARSIVN RVKVNESPHD KIIRDLRAEV 540
  541 DRLKSLRNEY ERQRRLSGNS NNPVPRKIII ETSVDETEVE ALRQQLAERE RELSRAQKSW 600
  601 MEKLKEAEDQ RKSELRVLKR RGLALELTAE QKQACLVNLT ADPILSGTLF YLLPQGLVRI 660
  661 GRGRLPGGSS SSQPDIVLDG PLVALQHCSI EHERGGKLYV IPGSEDFETY VNGELLKDRR 720
  721 QLFHGDRLVI GGSHYFRISN PFCSQRGKAD HPVDFQLAHQ EILQKQEQQL RSELEAEKRA 780
  781 ALTKIEQERA QHARDFEERL QCLELEQFKY KCNSEMLETE RQALALAQQQ EHTPLRHEDA 840
  841 VSTPAQKSTI LEDIQRIMLN PSEESLHKTQ LMVKEATQRC RQLDLPLEFR QTQTPDEFGL 900
  901 LRTVILILDK QRGLKAEWPT ARLGVWLDLV RDNAEQQEKL NATTIFQSVE VDWEPLDADL 960
  961 NETLSDTHNS SRIALNLSAM KDVLLNKPLK RLLNASSSKS NTPRQTSTPS PGSQLVHFTK1020
 1021 RLLTYDPEEI PESQSSFTTL VQQELQIMQR SAQRLRRHCE AALLERENHQ DNGVLAVSLQ1080
 1081 EALARMDTVL NGMHTSLARA EATACVTSPT KTQKAVRFLI D

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: neb-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: