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Protein Overview: FBpp0304538, CG1...

General Information:
Name(s) found: FBpp0304538 [FlyBase]
FBpp0304537 [FlyBase]
CG10664-PB / FBpp0080836 [FlyBase]
CG10664-PA / FBpp0080835 [FlyBase]
Description(s) found:
Found 45 descriptions.
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  • type=protein; loc=2L:join(19959280..19959691,19959751..19959887); ID=FBpp0304538; name=CoIV-PD; parent=FBgn0032833,FBtr0332243; dbxref=FlyBase:FBpp0304538,FlyBase_Annotation_IDs:CG10664-PD,REFSEQ:NP_001260613,GB_protein:AGB93148; MD5=5f9cd23e091851ec5fd0a1d5ca9af947; length=182; release=r5.56; species=Dmel; [FlyBase]
  • type=protein; loc=2L:join(19959280..19959691,19959751..19959887); ID=FBpp0304537; name=CoIV-PC; parent=FBgn0032833,FBtr0332242; dbxref=FlyBase:FBpp0304537,FlyBase_Annotation_IDs:CG10664-PC,REFSEQ:NP_001260612,GB_protein:AGB93147; MD5=5f9cd23e091851ec5fd0a1d5ca9af947; length=182; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG10664 (CG10664, FBgn0032833). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19958707..19960004. It has the cytological map location 38A8. Based on sequence similarity, it is predicted to have molecular function</span>: cytochrome-c oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, cytochrome c to oxygen. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG10664 (CG10664, FBgn0032833). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:19958707..19960004. It has the cytological map location 38A8. Based on sequence similarity, it is predicted to have molecular function</span>: cytochrome-c oxidase activity. Based on sequence similarity, it is predicted to be involved in the biological process</span>: mitochondrial electron transport, cytochrome c to oxygen. One allele is reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 182 amino acids

    Gene Ontology:
    Cellular Component: lipid particle [IDA]
    mitochondrion [ISS]
    mitochondrial respiratory chain complex IV [ISS]
    Biological Process: mitochondrial electron transport, cytochrome c to oxygen [ISS]
    Molecular Function: cytochrome-c oxidase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRLLNSAV LRQLASQLPK SAQVGSVAAV HTLDKIGKRE IVGYGWNGTA CYADRVDYPL  60
   61 PAVRFREPTN EINALRAKEQ GDWKKLSTQE IKALYRASFC QTIAEVQAGS GEWKLHLGVS 120
  121 LLFCAAAIWV AVLMNIFVYD ELPVTFDEEH QKAQLQRIID LEINPVTGLT SKWDYENKKW 180
  181 KN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..182] PSI-BLAST 60.39794 Mitochondrial cytochrome c oxidase subunit IV

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • cytochrome-c oxidase activity
    		•  12.8672436325695 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors
    		•  12.8672436325695 bayes_pls_golite062009
  • oxidoreductase activity, acting on heme group of donors, oxygen as acceptor
    		•  12.8672436325695 bayes_pls_golite062009
  • heme-copper terminal oxidase activity
    		•  12.5536631591417 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  6.39367011108548 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  6.23942388461757 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  5.62960572959435 bayes_pls_golite062009
  • oxidoreductase activity
    		•  5.40847023303734 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  5.36812403817205 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  5.16334360779969 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  4.74071132470389 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  4.53098112436118 bayes_pls_golite062009
  • binding
    		•  1.31836143571093 bayes_pls_golite062009
  • protein binding
    		•  0.603394316928236 bayes_pls_golite062009
  • catalytic activity
    		•  0.600497727931764 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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