YRC Public Data Repository - Protein Structure Prediction

Protein:	FBpp0304538, CG1...
Organism:	Drosophila melanogaster
Length:	182 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0304538, CG1....

Description	E-value	Query Range	Subject Range
gi\|124014034, gi... - gi\|32815847\|gb\|AAP88303.1\| cytochrome c oxidase polypeptide IV [Drosophila simulans], gi\|124014048\|g...	260.0	[0..1]	[182..1]
gi\|125984710, gi... - gi\|54644437\|gb\|EAL33178.1\| GA10478 [Drosophila pseudoobscura pseudoobscura], gi\|125984710\|ref\|XP_001... gi\|194103564, gi... - gi\|195161829\|ref\|XP_002021764.1\| GL26331 [Drosophila persimilis], gi\|194103564\|gb\|EDW25607.1\| GL2633... gi\|54644437\|gb\|E... - GA10478-PA [Drosophila pseudoobscura], GA10478 [Drosophila pseudoobscura pseudoobscura]	258.0	[0..1]	[182..1]
gi\|32815889 - gi\|32815889\|gb\|AAP88318.1\| cytochrome c oxidase polypeptide IV [Drosophila mauritiana]	256.0	[0..1]	[181..1]
COX41_RAT - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Rattus norvegicus GN=Cox4i1 PE=1 SV=1	249.0	[0..19]	[181..5]
COX41_RABIT - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Oryctolagus cuniculus GN=COX4I1 PE=2 SV=1	248.0	[0..17]	[181..3]
gi\|38382823 - gi\|38382823\|gb\|AAH62437.1\| Cytochrome c oxidase subunit IV isoform 1 [Homo sapiens]	247.0	[0..22]	[181..8]
COX41_MOUSE - Cytochrome c oxidase subunit 4 isoform 1, mitochondrial OS=Mus musculus GN=Cox4i1 PE=1 SV=2	246.0	[0..19]	[181..5]
gi\|57087091 - gi\|57087091\|ref\|XP_536759.1\| PREDICTED: similar to Cytochrome c oxidase subunit IV isoform 1, mitoch...	246.0	[0..22]	[181..8]

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Predicted Domain #1

Region A:
Residues: [1-182]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRLLNSAV LRQLASQLPK SAQVGSVAAV HTLDKIGKRE IVGYGWNGTA CYADRVDYPL  60
   61 PAVRFREPTN EINALRAKEQ GDWKKLSTQE IKALYRASFC QTIAEVQAGS GEWKLHLGVS 120
  121 LLFCAAAIWV AVLMNIFVYD ELPVTFDEEH QKAQLQRIID LEINPVTGLT SKWDYENKKW 180
  181 KN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.39794
Match:	1occD
Description:	Mitochondrial cytochrome c oxidase subunit IV
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cytochrome-c oxidase activity	12.8672436325695	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors	12.8672436325695	bayes_pls_golite062009
oxidoreductase activity, acting on heme group of donors, oxygen as acceptor	12.8672436325695	bayes_pls_golite062009
heme-copper terminal oxidase activity	12.5536631591417	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	6.39367011108548	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	6.23942388461757	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	5.62960572959435	bayes_pls_golite062009
oxidoreductase activity	5.40847023303734	bayes_pls_golite062009
cation transmembrane transporter activity	5.36812403817205	bayes_pls_golite062009
ion transmembrane transporter activity	5.16334360779969	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	4.74071132470389	bayes_pls_golite062009
substrate-specific transporter activity	4.53098112436118	bayes_pls_golite062009
binding	1.31836143571093	bayes_pls_golite062009
protein binding	0.603394316928236	bayes_pls_golite062009
catalytic activity	0.600497727931764	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: