Protein Overview: FBpp0303258, BicD-PA

General Information:
Name(s) found:	FBpp0303258 [FlyBase] BicD-PA / FBpp0080555 [FlyBase]
Description(s) found: Found 33 descriptions. SHOW ALL	type=protein; loc=2L:complement(17461726..17461843,17462168..17462342,17462429..17462683,17462738..17462955,17463032..17463882,17463988..17464125,17464190..17464555,17472097..17472324); ID=FBpp0303258; name=BicD-PC; parent=FBgn0000183,FBtr0330225; dbxref=FlyBase:FBpp0303258,FlyBase_Annotation_IDs:CG6605-PC,REFSEQ:NP_001260530,GB_protein:AGB93065; MD5=381801d7b76e6d035f8ca2ff747f63be; length=782; release=r5.56; species=Dmel; [FlyBase] The gene Bicaudal D is referred to in FlyBase by the symbol Dmel\BicD (CG6605, FBgn0000183). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:17460834..17473255. It has the cytological map location 36C9. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: oocyte microtubule cytoskeleton polarization; intracellular mRNA localization; germarium-derived oocyte fate determination; oogenesis; mRNA transport; RNA transport; germarium-derived egg chamber formation. 62 alleles are reported. The phenotypes of these alleles are annotated with 26 unique terms, many of which group under: organ system; anatomical structure; female germline cyst; egg; hemocyte; nervous system; embryonic tagma; peripheral nervous system; germarium; nuclear part; embryonic/larval hemocoel; embryonic head; blastoderm embryo; multi-cell-component structure; embryonic nervous system; embryonic thorax; cytoplasmic part; external compound sense organ. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	782 amino acids
Gene Ontology:
Cellular Component:	Golgi apparatus [IEA]
Biological Process:	germarium-derived egg chamber formation [IMP] intracellular mRNA localization [IMP][TAS] germarium-derived oocyte fate determination [IMP][TAS] oocyte nucleus migration during oocyte axis specification [TAS] oocyte microtubule cytoskeleton polarization [IMP] oocyte dorsal/ventral axis specification [TAS] oocyte anterior/posterior axis specification [TAS] oocyte axis specification [TAS] [NOT]germarium-derived female germ-line cyst formation [NAS] oogenesis [IMP][NAS][TAS] cell differentiation [NAS] RNA transport [IMP] mRNA transport [IDA][IMP] oocyte microtubule cytoskeleton organization [TAS]
Molecular Function:	protein binding [IPI] [NOT]mRNA binding [NAS] dynein binding [NAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSASNNGPS ADQSVQDLQM EVERLTRELD QVSSASAQSA QYGLSLLEEK SALQQKCEEL  60
   61 ETLYDNTRHE LDITQEALTK FQTSQKVTNK TGIEQEDALL NESAARETSL NLQIFDLENE 120
  121 LKQLRHELER VRNERDRMLQ ENSDFGRDKS DSEADRLRLK SELKDLKFRE TRMLSEYSEL 180
  181 EEENISLQKQ VSSLRSSQVE FEGAKHEIRR LTEEVELLNQ QVDELANLKK IAEKQMEEAL 240
  241 ETLQGEREAK YALKKELDGH LNRESMYHIS NLAYSIRSNM EDNASNNSDG EEENLALKRL 300
  301 EADLSTELKS PDGTKCDLFS EIHLNELKKL EKQLESMESE KTHLTANLRE AQTSLDKSQN 360
  361 ELQNFMSRLA LLAAHVDALV QLKKQIDVKE QGKEGGQKKD ELEQQLRALI SQYANWFTLS 420
  421 AKEIDGLKTD IAELQKGLNY TDATTTLRNE VTNLKNKLLA TEQKSLDLQS DVQTLTHISQ 480
  481 NAGQSLGSAR STLVALSDDL AQLYHLVCTV NGETPTRVLL DHKTDDMSFE NDSLTAIQSQ 540
  541 FKSDVFIAKP QIVEDLQGLA DSVEIKKYVD TVSDQIKYLK TAVEHTIDMN KHKIRSEGGD 600
  601 ALEKVNTEEM EELQEQIVKL KSLLSVKREQ IGTLRNVLKS NKQTAEVALT NLKSKYENEK 660
  661 IIVSDTMSKL RNELRLLKED AATFSSLRAM FAARCEEYVT QVDDLNRQLE AAEEEKKTLN 720
  721 QLLRLAVQQK LALTQRLEEM EMDREMRHVR RPMPAQRGTS GKSSFSTRPS SRNPASSNAN 780
  781 PF

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: FBpp0303258, BicD-PA

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: