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Protein Overview: FBpp0305438, Sfm...

General Information:
Name(s) found: FBpp0305438 [FlyBase]
Sfmbt-PB / FBpp0080070 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=2L:complement(13170452..13170784,13171382..13171665,13171739..13172250,13172316..13172565,13172643..13173941,13174439..13175276,13175667..13175813); ID=FBpp0305438; name=Sfmbt-PD; parent=FBgn0032475,FBtr0333236; dbxref=REFSEQ:NP_001260432,GB_protein:AGB92967,FlyBase:FBpp0305438,FlyBase_Annotation_IDs:CG16975-PD; MD5=3248378135959e7c579f5887727d9d23; length=1220; release=r5.56; species=Dmel; [FlyBase]
  • The gene Scm-related gene containing four mbt domains is referred to in FlyBase by the symbol Dmel\Sfmbt (CG16975, FBgn0032475). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:13169643..13176783. It has the cytological map location 34A7-34A8. There is experimental evidence that it has the molecular function</span>: protein binding; chromatin binding; methylated histone residue binding. There is experimental evidence that it is involved in the biological process</span>: negative regulation of gene expression; oogenesis; chromatin silencing; imaginal disc growth. 10 alleles are reported. The phenotypes of these alleles are annotated with: female germline stem cell; imaginal disc. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 1220 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: negative regulation of gene expression [IMP]
    oogenesis [IMP]
    chromatin silencing [IDA][IGI]
    regulation of transcription [IEA]
    imaginal disc growth [IMP]
    Molecular Function: zinc ion binding [IEA]
    protein binding [IPI]
    methylated histone residue binding [IDA]
    chromatin binding [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNPSELRMMW MSSQYNSERI TLEDAATLLG HPTVGLSVME DLSAHQPTLD MNPMMSLMGG  60
   61 DFTGQAAATA AALGVQPGTL IATNSNNLYG FAHMGGLQQQ LLQQSAAAAV FQNYAEAMDN 120
  121 DVENGMVGMA MEAVVDDDDQ VYGQRDNNFD DNGSELEPKQ EIINIDDFVM MNEDNNSYDG 180
  181 TDFMTSSDKD ISQSSSSCMA QMPGSLGVPG VEHDLLVPLP DGLLHHKLLG TTLVPAMGTL 240
  241 NGNAFGNIMV STENTSSKQM QRTYSTAKGA NSTATTATCS ASTSSALRSQ RKTRKIEPVN 300
  301 RPGLVLKTPI AYRGNIDPSV IPIQKDGMAV CKRCGAIGVK HTFYTKSRRF CSMACARGEL 360
  361 YSLVLNTKME GDQATTSSPD PGAGSESADL PGDQQQSQSD IELDLHAAHI KNANYRFRIT 420
  421 DQSKITQLNS FGEPMSMGGD AAANNVQMAA DETIAALNGG AVGDATAPGS TEEGASTPNS 480
  481 YLSAAPTPKA LRLFKDIYPQ DDLPQIPKYE RLPVPCPQME KIISIRRRMY DPTHSYDWLP 540
  541 RLSKENFNAA PVTCFPHAPG CEVWDNLGVG MKVEVENTDC DSIEVIQPGQ TPTSFWVATI 600
  601 LEIKGYKALM SYEGFDTDSH DFWVNLCNAE VHSVGWCATR GKPLIPPRTI EHKYKDWKDF 660
  661 LVGRLSGART LPSNFYNKIN DSLQSRFRLG LNLECVDKDR ISQVRLATVT KIVGKRLFLR 720
  721 YFDSDDGFWC HEDSPIIHPV GWATTVGHNL AAPQDYLERM LAGREAMIEV HEDDATIELF 780
  781 KMNFTFDEYY SDGKTNSFVE GMKLEAVDPL NLSSICPATV MAVLKFGYMM IRIDSYQPDA 840
  841 SGSDWFCYHE KSPCIFPAGF CSVNNISVTP PNGYDSRTFT WEGYLRDTGA VAAGQHLFHR 900
  901 IIPDHGFEVG MSLECADLMD PRLVCVATVA RVVGRLLKVH FDGWTDEYDQ WLDCESADIY 960
  961 PVGWCVLVNH KLEGPPRVAH QQAPKPAPKP KIQRKRKPKK GAAGGKTPTD NNTQSVKSRT1020
 1021 IALKTTPHLP KLSIKLELKP EHHNAAFYEN NQPEEEGDEE DPDADGDGDG STSHISEQST1080
 1081 TQSSSDLIAG SGSGSGSASL VTLATGSNKT NSSATNNKYI PRLADIDSSE PHLELVPDTW1140
 1141 NVYDVSQFLR VNDCTAHCDT FSRNKIDGKR LLQLTKDDIM PLLGMKVGPA LKISDLIAQL1200
 1201 KCKVNPGRAR SHKTNKSPFL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.83

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle