Protein Overview: FBpp0307451, FBp...

General Information:
Name(s) found:	FBpp0307451 [FlyBase] FBpp0293786 [FlyBase] crol-PA / FBpp0079845 [FlyBase]
Description(s) found: Found 32 descriptions. SHOW ALL	type=protein; loc=2L:complement(11797125..11797741,11797829..11798041,11798665..11799402,11800155..11800322,11802287..11803439); ID=FBpp0307451; name=crol-PI; parent=FBgn0020309,FBtr0335476; dbxref=REFSEQ:NP_001260393,GB_protein:AGB92928,FlyBase:FBpp0307451,FlyBase_Annotation_IDs:CG14938-PI; MD5=778788679cac64944c0c482fd0443a98; length=962; release=r5.56; species=Dmel; [FlyBase] type=protein; loc=2L:complement(11797125..11797741,11797829..11798041,11798665..11799402,11800155..11800322,11802287..11803439); ID=FBpp0293786; name=crol-PE; parent=FBgn0020309,FBtr0305262; dbxref=REFSEQ:NP_001245993,GB_protein:AFH03667,FlyBase:FBpp0293786,FlyBase_Annotation_IDs:CG14938-PE; MD5=778788679cac64944c0c482fd0443a98; length=962; release=r5.56; species=Dmel; [FlyBase] The gene crooked legs is referred to in FlyBase by the symbol Dmel\crol (CG14938, FBgn0020309). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11794327..11809433. It has the cytological map location 33A1-33A2. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; cell adhesion; negative regulation of Wnt receptor signaling pathway; regulation of transcription from RNA polymerase II promoter; imaginal disc-derived wing morphogenesis; positive regulation of mitotic cell cycle. 48 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; thoracic segment; organ system; peripheral nervous system; nervous system; dorsal thoracic disc; appendage segment; stage P14 pharate adult; larval thorax; multi-cell-component structure; wing pouch. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	962 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	negative regulation of transcription [IMP] imaginal disc-derived wing morphogenesis [IGI][IMP] cell adhesion [IMP] negative regulation of Wnt receptor signaling pathway [IGI] positive regulation of mitotic cell cycle [IMP] regulation of transcription from RNA polymerase II promoter [IMP][ISS]
Molecular Function:	nucleic acid binding [IEA] zinc ion binding [IEA] RNA polymerase II transcription factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHVSAASSV PSVVTPVVTT GGTTITLGGP PPLPKSEHKE DGKPPHGIEM YKVNIEDISQ  60
   61 LFTYHEVFGK IHGDVVNHQL AAAHGGQLPP PPPLPPQVTS HAASAAAAAA AASTNNAAVA 120
  121 AVMASANAAA AAAAAASAGG GLPPATSGNG GQQVTVTTTS SSTSSGGSTT SGGTTTTAGE 180
  181 LLMPKMEGGI HGVDGSGNGG NGGGQNVALA PDGTPIATGT HVCDICGKMF QFRYQLIVHR 240
  241 RYHSERKPFM CQVCGQGFTT SQDLTRHGKI HIGGPMFTCI VCFNVFANNT SLERHMKRHS 300
  301 TDKPFACTIC QKTFARKEHL DNHFRSHTGE TPFRCQYCAK TFTRKEHMVN HVRKHTGETP 360
  361 HRCDICKKSF TRKEHYVNHY MWHTGQTPHQ CDVCGKKYTR KEHLANHMRS HTNETPFRCE 420
  421 ICGKSFSRKE HFTNHILWHT GETPHRCDFC SKTFTRKEHL LNHVRQHTGE SPHRCSYCMK 480
  481 TFTRKEHLVN HIRQHTGETP FKCTYCTKAF TRKDHMVNHV RQHTGESPHK CTYCTKTFTR 540
  541 KEHLTNHVRQ HTGDSPHRCS YCKKTFTRKE HLTNHVRLHT GDSPHKCEYC QKTFTRKEHL 600
  601 NNHMRQHSSD NPHCCNVCNK PFTRKEHLIN HMSRCHTGDR PFTCETCGKS FPLKGNLLFH 660
  661 QRSHTKGQEM ERPFACEKCP KNFICKGHLV SHMRSHSGEK PHACTLCSKA FVERGNLKRH 720
  721 MKMNHPDAMM PPPPVHPHPQ IPAGVLTQVK QEVKPIIIPH HSATTTMHTI QQITAGAAGG 780
  781 AGAVQLTPGL VPLVTSTLIS HNAAAQQQSQ KQQAAAAAAA QQQAAAAAAA QQQAAQQQAA 840
  841 AAHQQHQQQV AAQHQQQAAV AAHQQQQQQL QQQQQLLQLS IQQAAHHHQQ EQHRQQQQQQ 900
  901 HQQQQQQQHH QQQQQGHPQA PPPQQQQQPP PIALISDPSA LARAAIQLQH LPANVEQHPV 960
  961 VY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: FBpp0307451, FBp...

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: