Protein Overview: crol-PD

General Information:
Name(s) found:	crol-PD / FBpp0079844 [FlyBase]
Description(s) found: Found 21 descriptions. SHOW ALL	The gene crooked legs is referred to in FlyBase by the symbol Dmel\crol (CG14938, FBgn0020309). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:11794327..11809433. It has the cytological map location 33A1-33A2. Based on sequence similarity, it is predicted to have molecular function</span>: RNA polymerase II transcription factor activity. There is experimental evidence that it is involved in the biological process</span>: negative regulation of transcription; cell adhesion; negative regulation of Wnt receptor signaling pathway; regulation of transcription from RNA polymerase II promoter; imaginal disc-derived wing morphogenesis; positive regulation of mitotic cell cycle. 48 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: adult segment; thoracic segment; organ system; peripheral nervous system; nervous system; dorsal thoracic disc; appendage segment; stage P14 pharate adult; larval thorax; multi-cell-component structure; wing pouch. It has 4 annotated transcripts and 4 annotated polypeptides. [FlyBase]
Organism:	Drosophila melanogaster
Length:	878 amino acids
Gene Ontology:
Cellular Component:	nucleus [IDA]
Biological Process:	negative regulation of transcription [IMP] imaginal disc-derived wing morphogenesis [IGI][IMP] cell adhesion [IMP] negative regulation of Wnt receptor signaling pathway [IGI] positive regulation of mitotic cell cycle [IMP] regulation of transcription from RNA polymerase II promoter [IMP][ISS]
Molecular Function:	nucleic acid binding [IEA] zinc ion binding [IEA] RNA polymerase II transcription factor activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQHVSAASSV PSVVTPVVTT GGTTITLGGP PPLPKSEHKE DGKPPHGIEM YKVNIEDISQ  60
   61 LFTYHEVFGK IHGDVVNHQL AAAHGGQLPP PPPLPPQVTS HAASAAAAAA AASTNNAAVA 120
  121 AVMASANAAA AAAAAASAGG GLPPATSGNG GQQVTVTTTS SSTSSGGSTT SGGTTTTAGE 180
  181 LLMPKMEGGI HGVDGSGNGG NGGGQNVALA PDGTPIATGT HVCDICGKMF QFRYQLIVHR 240
  241 RYHSERKPFM CQVCGQGFTT SQDLTRHGKI HIGGPMFTCI VCFNVFANNT SLERHMKRHS 300
  301 TDKPFACTIC QKTFARKEHL DNHFRSHTGE TPFRCQYCAK TFTRKEHMVN HVRKHTGETP 360
  361 HRCDICKKSF TRKEHYVNHY MWHTGETPHR CDFCSKTFTR KEHLLNHVRQ HTGESPHRCS 420
  421 YCMKTFTRKE HLVNHIRQHT GESPHKCTYC TKTFTRKEHL TNHVRQHTGD SPHRCSYCKK 480
  481 TFTRKEHLTN HVRLHTGDSP HKCEYCQKTF TRKEHLNNHM RQHSSDNPHC CNVCNKPFTR 540
  541 KEHLINHMSR CHTGDRPFTC ETCGKSFPLK GNLLFHQRSH TKGQEMERPF ACEKCPKNFI 600
  601 CKGHLVSHMR SHSGEKPHAC TLCSKAFVER GNLKRHMKMN HPDAMMPPPP VHPHPQIPAG 660
  661 VLTQVKQEVK PIIIPHHSAT TTMHTIQQIT AGAAGGAGAV QLTPGLVPLV TSTLISHNAA 720
  721 AQQQSQKQQA AAAAAAQQQA AAAAAAQQQA AQQQAAAAHQ QHQQQVAAQH QQQAAVAAHQ 780
  781 QQQQQLQQQQ QLLQLSIQQA AHHHQQEQHR QQQQQQHQQQ QQQQHHQQQQ QGHPQAPPPQ 840
  841 QQQQPPPIAL ISDPSALARA AIQLQHLPAN VEQHPVVY

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: crol-PD

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: