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Protein Overview: CG4594-PA, FBpp0...

General Information:
Name(s) found: FBpp0304021 [FlyBase]
CG4594-PA / FBpp0079474 [FlyBase]
Description(s) found:
Found 27 descriptions.
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  • type=protein; loc=2L:join(9920374..9920601,9920654..9920800,9920854..9921321); ID=FBpp0304021; name=CG4594-PB; parent=FBgn0032161,FBtr0331631; dbxref=FlyBase:FBpp0304021,FlyBase_Annotation_IDs:CG4594-PB,REFSEQ:NP_001260305,GB_protein:AGB92840; MD5=b3b0f1ba5186b2ee3a7d296a4cfe72a6; length=280; release=r5.56; species=Dmel; [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG4594 (CG4594, FBgn0032161). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9920351..9921470. It has the cytological map location 30E4-30F1. Based on sequence similarity, it is predicted to have molecular function</span>: dodecenoyl-CoA delta-isomerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process</span>: metabolic process. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 280 amino acids

    Gene Ontology:
    Cellular Component: mitochondrion [ISS]
    Biological Process: metabolic process [IEA]
    Molecular Function: dodecenoyl-CoA delta-isomerase activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRSNFLRLM AHGAPSRLMS TATKLTTVEI NDKTGIATLT MNRPPVNSQN VQLLLDLQTS  60
   61 ISEIENNKSR GLILTSASSN VFSAGLDIFE MYNTDVERLR TVWTELQNVW IALYGTTLPT 120
  121 AAAINGHAPA GGCLLATACE YRVMRPNFLI GLNEAQLGII APKWLMSGFA SILPKRVAER 180
  181 ALTQGRMFTT QEAFEVGLID EIASSKEEAL EKCAAFIGTF AKVNPLARGL TKLQFRGDNI 240
  241 KEFEMIREKD IADFVALASS PGVQKVMGAY LENLKNKVKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..280] PSI-BLAST 43.69897 Crystal Structure of Rat Mitochondrial 3,2-Enoyl-CoA

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • enoyl-CoA hydratase activity
    		•  3.92947460544831 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  3.59076614105466 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  3.4980371783229 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  3.34692152434862 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  2.44182589784656 bayes_pls_golite062009
  • dodecenoyl-CoA delta-isomerase activity
    		•  1.80820904754223 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • propionyl-CoA carboxylase activity
    		•  1.20853698666984 bayes_pls_golite062009
  • ligase activity
    		•  0.98581896521131 bayes_pls_golite062009
  • 3-hydroxybutyryl-CoA epimerase activity
    		•  0.241955774397835 bayes_pls_golite062009
  • long-chain-3-hydroxyacyl-CoA dehydrogenase activity
    		•  0.21557465194387 bayes_pls_golite062009
  • racemase and epimerase activity, acting on hydroxy acids and derivatives
    		•  0.099208209617217 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing C=C bonds
    		•  0.0918189681606029 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.62

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle