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Protein Overview: FBpp0307465, hoip-PA

General Information:
Name(s) found: FBpp0307465 [FlyBase]
hoip-PA / FBpp0079443 [FlyBase]
Description(s) found:
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  • gi|6636516|gb|AAF20209.1|AF208396_1 Hoi-polloi [Drosophila melanogaster] [NCBI NR]
  • gi|17864298|ref|NP_524714.1| hoi-polloi [Drosophila melanogaster] [NCBI NR]
  • gi|13431749|sp|Q9U3Z7.1|NH2L1_DROME RecName: Full=NHP2-like protein 1 homolog; AltName: Full=Protein hoi-polloi [NCBI NR]
  • gi|10728689|gb|AAF52798.2| hoi-polloi [Drosophila melanogaster] [NCBI NR]
  • (Q9U3Z7) NHP2-like protein (Hoi-polloi protein) [Swiss-Prot]
  • NHP2-like protein 1 homolog OS=Drosophila melanogaster GN=hoip PE=2 SV=1 [Swiss-Prot]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0307465; name=hoip-PB; parent=FBgn0015393,FBtr0335494; dbxref=REFSEQ:NP_001260293,GB_protein:AGB92828,FlyBase:FBpp0307465,FlyBase_Annotation_IDs:CG3949-PB; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r5.56; species=Dmel; [FlyBase]
  • The gene hoi-polloi is referred to in FlyBase by the symbol Dmel\hoip (CG3949, FBgn0015393). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9699791..9700459. It has the cytological map location 30C5. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development. 9 alleles are reported. The phenotypes of these alleles are annotated with: fascicle; embryonic peripheral nervous system; imaginal disc. It has one annotated transcript and one annotated polypeptide. [FlyBase]
  • >CG3949-PA translation from_gene[CG3949 hoip FBgn0015393] seq_release:3 mol_weight=13883 cds_boundaries:(2L:9,692,164..9,692,606[+]) aa_length:127 transcript_info:[CG3949-RA seq_release:3] gene_info:[gene symbol:hoip FBgn0015393 gene_boundaries:(2L:9,6 [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003625) hoip gene product [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG3949-PA [Drosophila melanogaster]gi|17864298|ref|NP_524714.1| CG3949-PA [Drosophila melanogaster]gi|6636516|gb|AAF20209.1| Hoi-polloi [Drosophila melanogaster]gi|13431749|sp|Q9U3Z7|NHPX_DROME NHP2-like protein (Hoi-polloi protein) [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798; MD5=43324db [fly-100309-contam.fasta]
  • NHP2-like protein (Hoi-polloi protein) [nr-271106-contam.fasta]
  • hoi-polloi CG3949-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Hoi-polloi [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG3949-PA [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • NHP2-like protein 1 homolog OS=Drosophila melanogaster GN=hoip PE=1 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • RE51843p OS=Drosophila melanogaster GN=hoip-RA PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798,FlyMine:FBpp0079443,modMine:FBpp0079443; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798,FlyMine:FBpp0079443,modMine:FBpp0079443; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0307465; name=hoip-PB; parent=FBgn0015393,FBtr0335494; dbxref=REFSEQ:NP_001260293,GB_protein:AGB92828,FlyBase:FBpp0307465,FlyBase_Annotation_IDs:CG3949-PB; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798,FlyMine:FBpp0079443,modMine:FBpp0079443; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0307465; name=hoip-PB; parent=FBgn0015393,FBtr0335494; dbxref=REFSEQ:NP_001260293,GB_protein:AGB92828,FlyBase:FBpp0307465,FlyBase_Annotation_IDs:CG3949-PB; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q9U3Z7, Hoi-polloi, isoform B OS=Drosophila melanogaster GN=hoip PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0079443 type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798,FlyMine:FBpp0079443,modMine:FBpp0079443; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0307465 type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0307465; name=hoip-PB; parent=FBgn0015393,FBtr0335494; dbxref=REFSEQ:NP_001260293,GB_protein:AGB92828,FlyBase:FBpp0307465,FlyBase_Annotation_IDs:CG3949-PB; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0079443; name=hoip-PA; parent=FBgn0015393,FBtr0079846; dbxref=FlyBase:FBpp0079443,FlyBase_Annotation_IDs:CG3949-PA,GB_protein:AAF52798.2,REFSEQ:NP_524714,GB_protein:AAF52798,UniProt/Swiss-Prot:Q9U3Z7,FlyMine:FBpp0079443,modMine:FBpp0079443; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0307465; name=hoip-PB; parent=FBgn0015393,FBtr0335494; dbxref=REFSEQ:NP_001260293,GB_protein:AGB92828,FlyBase:FBpp0307465,FlyBase_Annotation_IDs:CG3949-PB,UniProt/Swiss-Prot:Q9U3Z7; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 127 amino acids

    Gene Ontology:
    Cellular Component: nucleus [NAS]
    precatalytic spliceosome [IDA]
    spliceosomal complex [ISS]
    small nuclear ribonucleoprotein complex [ISS]
    Biological Process: nervous system development [IMP]
    peripheral nervous system development [TAS]
    ribosome biogenesis [IEA]
    nuclear mRNA splicing, via spliceosome [IC][ISS]
    Molecular Function: mRNA binding [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTEEVNPKAF PLADAQLTAK IMNLLQQALN YNQLRKGANE ATKTLNRGLA DIVVLAGDAE  60
   61 PIEILLHLPL LCEDKNVPYV FVRSKQALGR ACGVSRPIVA CSVTTNEGSQ LKSQITSIQQ 120
  121 EIERLLV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..127] PSI-BLAST 33.0 No description for 1zwzA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
    		• 5.75333813716704 bayes_pls_golite062009
  • RNA binding
    		•  5.39762744650785 bayes_pls_golite062009
  • snoRNA binding
    		•  4.95788328272916 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.68798692352408 bayes_pls_golite062009
  • structural molecule activity
    		•  3.12718364266877 bayes_pls_golite062009
  • mRNA binding
    		•  2.62944559104613 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.39301463005357 bayes_pls_golite062009
  • binding
    		•  2.34187530323842 bayes_pls_golite062009
  • protein binding
    		•  0.381324299701367 bayes_pls_golite062009
  • catalytic activity
    		•  0.264002643439785 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle