Protein Overview: FBpp0307465, hoip-PA

General Information:
Name(s) found:	FBpp0307465 [FlyBase] hoip-PA / FBpp0079443 [FlyBase]
Description(s) found: Found 31 descriptions. SHOW ALL	type=protein; loc=2L:join(9699935..9699937,9700000..9700380); ID=FBpp0307465; name=hoip-PB; parent=FBgn0015393,FBtr0335494; dbxref=REFSEQ:NP_001260293,GB_protein:AGB92828,FlyBase:FBpp0307465,FlyBase_Annotation_IDs:CG3949-PB; MD5=43324dbc09fbb618991714f746bad42b; length=127; release=r5.56; species=Dmel; [FlyBase] The gene hoi-polloi is referred to in FlyBase by the symbol Dmel\hoip (CG3949, FBgn0015393). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:9699791..9700459. It has the cytological map location 30C5. Based on sequence similarity, it is predicted to have molecular function</span>: mRNA binding. There is experimental evidence that it is involved in the biological process</span>: nervous system development. 9 alleles are reported. The phenotypes of these alleles are annotated with: fascicle; embryonic peripheral nervous system; imaginal disc. It has one annotated transcript and one annotated polypeptide. [FlyBase]
Organism:	Drosophila melanogaster
Length:	127 amino acids
Gene Ontology:
Cellular Component:	nucleus [NAS] precatalytic spliceosome [IDA] spliceosomal complex [ISS] small nuclear ribonucleoprotein complex [ISS]
Biological Process:	nervous system development [IMP] peripheral nervous system development [TAS] ribosome biogenesis [IEA] nuclear mRNA splicing, via spliceosome [IC][ISS]
Molecular Function:	mRNA binding [ISS]

Sequence:
Sequence: [PDR BLAST] [ProtParam]	1 11 21 31 41 51 \| \| \| \| \| \| 1 MTEEVNPKAF PLADAQLTAK IMNLLQQALN YNQLRKGANE ATKTLNRGLA DIVVLAGDAE 60 61 PIEILLHLPL LCEDKNVPYV FVRSKQALGR ACGVSRPIVA CSVTTNEGSQ LKSQITSIQQ 120 121 EIERLLV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..127]	PSI-BLAST	33.0	No description for 1zwzA was found.

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
	5.75333813716704	bayes_pls_golite062009
RNA binding	5.39762744650785	bayes_pls_golite062009
snoRNA binding	4.95788328272916	bayes_pls_golite062009
structural constituent of ribosome	3.68798692352408	bayes_pls_golite062009
structural molecule activity	3.12718364266877	bayes_pls_golite062009
mRNA binding	2.62944559104613	bayes_pls_golite062009
nucleic acid binding	2.39301463005357	bayes_pls_golite062009
binding	2.34187530323842	bayes_pls_golite062009
protein binding	0.381324299701367	bayes_pls_golite062009
catalytic activity	0.264002643439785	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle