Protein Overview: TepII-PB

General Information:
Name(s) found:	TepII-PB / FBpp0079134 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|24582557\|ref\|NP_723298.1\| thiolester containing protein II, isoform B [Drosophila melanogaster] [NCBI NR] gi\|22945881\|gb\|AAF52539.2\| thiolester containing protein II, isoform B [Drosophila melanogaster] [NCBI NR] The gene Thiolester containing protein II is referred to in FlyBase by the symbol Dmel\TepII (CG7052, FBgn0041182). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:7693800..7701585. It has the cytological map location 28C1. Based on sequence similarity, it is predicted to have molecular function</span>: peptidase inhibitor activity. There is experimental evidence that it is involved in the biological process</span>: defense response to Gram-negative bacterium; antibacterial humoral response; phagocytosis, engulfment. 3 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase] >CG7052-PB translation from_gene[CG7052 TepII FBgn0041182] seq_release:3 mol_weight=155785 cds_boundaries:(2L:7,686,142..7,693,652[-]) aa_length:1399 transcript_info:[CG7052-RB seq_release:3] gene_info:[gene symbol:TepII synonyms:[CG18589] FBgn0041182 [hmr_yeast5_DM3-1_pombe.fasta] (Q9VLY9) CG7052 protein [DrosMelano7227.FASTAC.txt] CG7052-PB, isoform B [Drosophila melanogaster]gi\|24582557\|ref\|NP_723298.1\| CG7052-PB [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697007..7697157,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079134; name=TepII-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp007 [fly-100309-contam.fasta] Thiolester containing protein II CG7052-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] CG7052-PB, isoform B [Drosophila melanogaster] [nr-271106-contam.fasta] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697007..7697157,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079134; name=TepII-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697007..7697157,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079134; name=TepII-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] Thiolester containing protein II, isoform B OS=Drosophila melanogaster GN=TepII PE=2 SV=2 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=2L:complement(7693908..7694996,7695073..7695971,7696028..7696206,7697007..7697157,7698725..7698992,7699055..7699316,7699379..7700668,7701360..7701421); ID=FBpp0079134; name=TepII-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539,FlyMine:FBpp0079134,modMine:FBpp0079134; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=2L:complement(join(7701360..7701421,7699379..7700668,7699055..7699316,7698725..7698992,7697007..7697157,7696028..7696206,7695073..7695971,7693908..7694996)); ID=FBpp0079134; name=Tep2-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539,FlyMine:FBpp0079134,modMine:FBpp0079134; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=2L:complement(join(7701360..7701421,7699379..7700668,7699055..7699316,7698725..7698992,7697007..7697157,7696028..7696206,7695073..7695971,7693908..7694996)); ID=FBpp0079134; name=Tep2-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539,FlyMine:FBpp0079134,modMine:FBpp0079134; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9NFV7, Thioester-containing protein 2, isoform B OS=Drosophila melanogaster GN=Tep2 PE=1 SV=2 [DROME.fasta.20160308] FBpp0079134 type=protein; loc=2L:complement(join(7701360..7701421,7699379..7700668,7699055..7699316,7698725..7698992,7697007..7697157,7696028..7696206,7695073..7695971,7693908..7694996)); ID=FBpp0079134; name=Tep2-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539,FlyMine:FBpp0079134,modMine:FBpp0079134; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=2L:complement(join(7701360..7701421,7699379..7700668,7699055..7699316,7698725..7698992,7697007..7697157,7696028..7696206,7695073..7695971,7693908..7694996)); ID=FBpp0079134; name=Tep2-PB; parent=FBgn0041182,FBtr0079511; dbxref=FlyBase:FBpp0079134,FlyBase_Annotation_IDs:CG7052-PB,GB_protein:AAF52539.2,REFSEQ:NP_723298,GB_protein:AAF52539,UniProt/TrEMBL:Q9VLY9,FlyMine:FBpp0079134,modMine:FBpp0079134; MD5=aa8c92ff01ff6593b19da6e6b117f9c0; length=1399; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	1399 amino acids
Gene Ontology:
Cellular Component:	extracellular space [IEA]
Biological Process:	phagocytosis, engulfment [IMP] defense response to Gram-negative bacterium [IMP] antibacterial humoral response [IDA]
Molecular Function:	peptidase inhibitor activity [ISS] protein binding [IEA] endopeptidase inhibitor activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRIFLTGII LQYALLVNAT GIYSVVGPGT LRSNSKYNVV VSVHKADGPS QIKVSLNGPS  60
   61 YNETKQIELP PMSTQNVEFE VPKLATGNYN LSAEGVSGVV FKNSTKLNYA DKKPSVFVQT 120
  121 DKATYKPADL VQFRILFLDE NTRPAKIEKP ISVIIIDGAQ NRIKQLSDVK LTKGVFSGEL 180
  181 QLSEQPVLGT WKISVSVDGD NRETKSFEVD KYVLPKFEVI VDTPKAVVIA DKVIKATIRA 240
  241 KYTYGKPVKG KATVSMERSY GYFGDLNANG NKQEKTIDVD GKGHVEFDII HWAQRGQYLP 300
  301 PIKLFAVVTE ELTGNKQNAT ATVVLHQQRY SIEPYERPEH FEANKSFIYQ VVVKNVDGSP 360
  361 VTNSAKNVKI GFDKSYSYFH EPSPKTRINF EAPVNENGIA TFNVRLPDSD SRYYRIFASF 420
  421 DGSENTIGSI SKFEPTPMSR EPLKIQVNTK KPRLGEQVSF DVVSIEDLPY FVYTIVARGN 480
  481 VILSDYVDVP DGQKTYTVKF TPTFSMVPKA TIYVYYVVNN DLQFEEKTID FEKEFSNSID 540
  541 VSAPTNAKPS EEVKLRIKTD ADSFVGLLGV DQSVLLLKSG NDLSQDDIFN SLNIYQTSTP 600
  601 WMNGYGRYPG QTSGLVTLTN ANYPYNTERR IFIRPGIGFP RPLFNRVTVA GSLPPNVIPE 660
  661 PQVRKEFPEN WIFNIFENVG EEEFTLTKKI PDTITSWVVT GFSLNPTSGI ALTKNPSKIR 720
  721 VFQPFFVSTN LPYSVKRGEV IAIPVVIFNY LDKTLDADVV MDNSDQEYEF TEATNEVLEK 780
  781 AIDEVRRVKR VTIPANSGKS VSFMIRPKNV GFTTLKITAT SALAGDAIHQ KLKVEPEGVT 840
  841 LFENRAVFIN LKDQPEMSQS LDADIPNEVV PQSEFIEFSV VGDLLGPTLQ NLDNLVRMPY 900
  901 GCGEQNMVNF VPNILVLKYL EVTGRKLPSV ESKARKFLEI GYQRELTYKH DDGSYSAFGK 960
  961 SDASGSTWLT AYVMRSFHQA GTYTDIDPKV ITAGLDFLVS KQKESGEFPE VGKLFDNANQ1020
 1021 NPLALTSFVL LAFFENHELI PKYQSAIKKA VRYVAEEADK TDDQYSLAIA AVALQLAKHP1080
 1081 QSEKVIAKLE SVARKENDRM WWSKATESTG EDGRVFHWKP RSNDVEITSY VLLALLEKDP1140
 1141 AEKALPIIKW LISQRNSNGG FSSTQDTVIG LQALTKFAYK TGSGSGTMDI EFSSAGESKN1200
 1201 TIKVNPENSL VLQTHDLPKS TRKVDFTAKG TGSAMVQLSY RYNLAEKEKK PSFKVTPTVK1260
 1261 DTPNQLLIVD VCAEYVPLED ADKDKDSNMA VMEIALPSGF VGDSTSLGKI QAVDRVKRVE1320
 1321 TKNSDSTVVV YFDSLTPGDV RCLPLEASKA HAVAKQKPAS VSLYDYYDTE RKATEYYQVK1380
 1381 SSLCDICEGA DCGEGCKKD

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: TepII-PB

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: