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Protein Overview: Mnn1-PA, Mnn1-PC

General Information:
Name(s) found: Mnn1-PC / FBpp0110277 [FlyBase]
Mnn1-PA / FBpp0079029 [FlyBase]
Description(s) found:
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  • gi|28574051|ref|NP_523498.2| menin 1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|28380303|gb|AAF52480.3| menin 1, isoform A [Drosophila melanogaster] [NCBI NR]
  • gi|116007292|ref|NP_001036342.1| menin 1, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|113194963|gb|ABI31296.1| menin 1, isoform C [Drosophila melanogaster] [NCBI NR]
  • The gene Menin 1 is referred to in FlyBase by the symbol Dmel\Mnn1 (CG13778, FBgn0031885). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:7056306..7063406. It has the cytological map location 27D7. Its molecular function is unknown. There is experimental evidence for 12 unique biological process</span> terms, many of which group under: response to stress; response to chemical stimulus; anatomical structure development; response to DNA damage stimulus; response to abiotic stimulus; organ development; regulation of response to stimulus; response to ionizing radiation; positive regulation of MAPKKK cascade; cellular macromolecule metabolic process; determination of adult lifespan; negative regulation of MAPKKK cascade; response to salt stress. 19 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; chaeta; distiproboscis; wing. It has 3 annotated transcripts and 3 annotated polypeptides. [FlyBase]
  • >CG13778-PA translation from_gene[CG13778 Mnn1 FBgn0031885] seq_release:3 mol_weight=82866 cds_boundaries:(2L:7,049,638..7,053,949[+]) aa_length:763 transcript_info:[CG13778-RA seq_release:3] gene_info:[gene symbol:Mnn1 FBgn0031885 gene_boundaries:(2L: [hmr_yeast5_DM3-1_pombe.fasta]
  • (AAF52480) CG13778-PA [DrosMelano7227.FASTAC.txt]
  • CG13778-PA, isoform A [Drosophila melanogaster]gi|28574051|ref|NP_523498.2| CG13778-PA [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31 [fly-100309-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_5234 [fly-100309-contam.fasta]
  • CG13778-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Menin 1 CG13778-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Menin 1 CG13778-PA, isoform A [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG13778-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Menin 1, isoform A OS=Drosophila melanogaster GN=Mnn1 PE=4 SV=3 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480,FlyMine:FBpp0079029,modMine:FBpp0079029; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480,FlyMine:FBpp0079029,modMine:FBpp0079029; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480,FlyMine:FBpp0079029,modMine:FBpp0079029; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Menin 1, isoform A OS=Drosophila melanogaster GN=Mnn1 PE=1 SV=3 [DROME.fasta.20160308]
  • FBpp0110277 type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0079029 type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480,FlyMine:FBpp0079029,modMine:FBpp0079029; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0110277; name=Mnn1-PC; parent=FBgn0031885,FBtr0110978; dbxref=FlyBase:FBpp0110277,FlyBase_Annotation_IDs:CG13778-PC,REFSEQ:NP_001036342,GB_protein:ABI31296,UniProt/TrEMBL:Q9VM47; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:join(7057407..7057674,7057864..7058325,7058393..7059198,7060966..7061721); ID=FBpp0079029; name=Mnn1-PA; parent=FBgn0031885,FBtr0079401; dbxref=FlyBase:FBpp0079029,FlyBase_Annotation_IDs:CG13778-PA,GB_protein:AAF52480.3,REFSEQ:NP_523498,GB_protein:AAF52480,UniProt/TrEMBL:Q9VM47,FlyMine:FBpp0079029,modMine:FBpp0079029; MD5=6a7bd1f13aaddd1960b57ba54c5fc515; length=763; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 763 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: response to oxidative stress [IMP]
    response to heat [IMP]
    imaginal disc fusion, thorax closure [IMP]
    response to hypoxia [IMP]
    response to salt stress [IMP]
    determination of adult lifespan [IMP]
    positive regulation of JNK cascade [IGI]
    nucleotide-excision repair [IMP]
    response to DNA damage stimulus [IMP]
    negative regulation of JNK cascade [IGI]
    proboscis development [IMP]
    response to ionizing radiation [IMP]
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTITRSASA SPMALNGVID ASLFPLKSTA DVINLFRRAL TSGIEPDLTL LSIVVGYIEL  60
   61 SLTTGEAAAQ AAQAAAAAVA AGDISQATTG GNDIIMGNSV PFPVVTHELI AGLYKKFQTI 120
  121 LSVVEKPKPH RQATREVIKK VSDVIWNSLI RSSYKDRAHL QNLYSYLSGN KLDCFGVALA 180
  181 VVAGCQLLGY KDVRLAISED HAWVVFGQKR VETIEVTWHG KGSEDKRGQD IRPGIESGSW 240
  241 LYLGGLAVVC ERGMEVAAIC AALNISLTSN SDCVEVAELQ QQLLWLLYDL GHLKRYPMAL 300
  301 GTLGELEEIH RTHPSISCEQ LYREAIESAR THYRNHHVYP YTYQGNYYNR LLKYRDAFAA 360
  361 WANAADVIRL YTYQCRDDEE IYKELLDIAN ELIPYVMKTE SSGHSARSIL RDSEVFANLL 420
  421 RFYDGICQWE EDSLTPILHI GWAKPLVNNI TKFDYDIRSQ VVIKLPEDLE AEQAKAELAR 480
  481 AEQEAKEAKE SKEAAGSEAM EGNNNRMATK EEKSKNSELP TTLADLTAAC GEKILNPDFL 540
  541 LQGGGQPFAD QKQQPSGGES DNPELHNNNN NSNSNNNNNN HNADKKEAAA TTTNATTTSN 600
  601 GSGTSVQLPV SSEANNAGQA QSQVQINDQL GKPQHKEAKK EETSDDYDPF EIMLKRPVIT 660
  661 LYSQKMKGLK DLLLAEKLNT HAISLQVTAQ SVASRKVRGV EKHSATISAT ITAISSSSGD 720
  721 SVLSGVGGGG GSGSAVTGGA SLASSSLGGD SIAASRPKRT RRE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.28

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle