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Protein Overview: nrv2-PC, nrv2-PF...

General Information:
Name(s) found: FBpp0304645 [FlyBase]
nrv2-PF / FBpp0099794 [FlyBase]
nrv2-PC / FBpp0079009 [FlyBase]
Description(s) found:
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  • gi|62471615|ref|NP_001014475.1| nervana 2, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|61678289|gb|AAX52659.1| nervana 2, isoform F [Drosophila melanogaster] [NCBI NR]
  • gi|22945809|gb|AAN10600.1| nervana 2, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|17137212|ref|NP_477168.1| nervana 2, isoform C [Drosophila melanogaster] [NCBI NR]
  • gi|16648126|gb|AAL25328.1| GH13134p [Drosophila melanogaster] [NCBI NR]
  • gi|12643737|sp|Q24048.2|ATPB2_DROME RecName: Full=Sodium/potassium-transporting ATPase subunit beta-2; AltName: Full=Sodium/potassium-dependent ATPase subunit beta-2; AltName: Full=Protein nervana 2 [NCBI NR]
  • Sodium/potassium-transporting ATPase subunit beta-2 OS=Drosophila melanogaster GN=nrv2 PE=1 SV=2 [Swiss-Prot]
  • (Q24048) Sodium/potassium-transporting ATPase beta-2 chain (Sodium/potassium-dependent ATPase beta-2 subunit) (Protein nervana 2) [Swiss-Prot]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0304645; name=nrv2-PG; parent=FBgn0015777,FBtr0332369; dbxref=FlyBase:FBpp0304645,FlyBase_Annotation_IDs:CG9261-PG,REFSEQ:NP_001260164,GB_protein:AGB92700; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.56; species=Dmel; [FlyBase]
  • The gene nervana 2 is referred to in FlyBase by the symbol Dmel\nrv2 (CG9261, FBgn0015777). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2L:6789761..6798864. It has the cytological map location 27B1-27B2. There is experimental evidence that it has the molecular function</span>: sodium:potassium-exchanging ATPase activity; cation transmembrane transporter activity. There is experimental evidence that it is involved in the biological process</span>: regulation of tube diameter, open tracheal system; regulation of tube size, open tracheal system; establishment of glial blood-brain barrier; open tracheal system development; regulation of tube length, open tracheal system; cation transport; septate junction assembly. 24 alleles are reported. The phenotypes of these alleles are annotated with: embryonic trachea; embryonic dorsal trunk; embryonic salivary gland; embryonic somatic muscle; embryonic/larval dorsal trunk; septate junction; embryonic/larval tracheal system; embryonic/larval transverse connective; embryonic ganglionic branch. It has 5 annotated transcripts and 5 annotated polypeptides. [FlyBase]
  • >CG9261-PC translation from_gene[CG9261 Nrv2 FBgn0015777] seq_release:3 mol_weight=37284 cds_boundaries:(2L:6,782,858..6,788,697[-]) aa_length:323 transcript_info:[CG9261-RC seq_release:3] gene_info:[gene symbol:Nrv2 FBgn0015777 gene_boundaries:(2L:6,7 [hmr_yeast5_DM3-1_pombe.fasta]
  • (AE003615) Nrv2 gene product [alt 1] [Drosophila melanogaster] [yeastflysequest.fasta]
  • CG9261-PC, isoform C [Drosophila melanogaster]gi|16648126|gb|AAL25328.1| GH13134p [Drosophila melanogaster]gi|17137212|ref|NP_477168.1| CG9261-PC [Drosophila melanogaster]gi|12643737|sp|Q24048|ATB2_DROME Sodium/potassium-transporting ATPase beta-2 chai [nrdb_11152004_Chlamydomonas]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261- [fly-100309-contam.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp00997 [fly-100309-contam.fasta]
  • nervana 2 CG9261-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG9261-PF, isoform F [Drosophila melanogaster] [nr-271106-contam.fasta]
  • nervana 2 CG9261-PF, isoform F [Drosophila melanogaster] [nr-271106-contam.fasta]
  • CG9261-PC, isoform C [Drosophila melanogaster] [nr-271106-contam.fasta]
  • GH13134p [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Sodium/potassium-transporting ATPase subunit beta-2 (Sodium/potassium-dependent ATPase beta-2 subunit) (Protein nervana 2) [nr-271106-contam.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.16; species=Dmel; [fly-contam-His-TEV-Tub4complex.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta]
  • Nervana 2, isoform F OS=Drosophila melanogaster GN=nrv2 PE=3 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659,FlyMine:FBpp0099794,modMine:FBpp0099794; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(6790639..6790742,6790799..6790967,6791031..6791323,6791518..6791637,6791701..6791841,6796337..6796481); ID=FBpp0304645; name=nrv2-PG; parent=FBgn0015777,FBtr0332369; dbxref=FlyBase:FBpp0304645,FlyBase_Annotation_IDs:CG9261-PG; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659,FlyMine:FBpp0099794,modMine:FBpp0099794; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0304645; name=nrv2-PG; parent=FBgn0015777,FBtr0332369; dbxref=FlyBase:FBpp0304645,FlyBase_Annotation_IDs:CG9261-PG,REFSEQ:NP_001260164,GB_protein:AGB92700; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659,FlyMine:FBpp0099794,modMine:FBpp0099794; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0304645; name=nrv2-PG; parent=FBgn0015777,FBtr0332369; dbxref=FlyBase:FBpp0304645,FlyBase_Annotation_IDs:CG9261-PG,REFSEQ:NP_001260164,GB_protein:AGB92700; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.07; species=Dmel; [fly-08202015-contam.fasta]
  • Isoform of Q24048, Nervana 2, isoform F OS=Drosophila melanogaster GN=nrv2 PE=1 SV=1 [DROME.fasta.20160308]
  • FBpp0079009 type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0099794 type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659,FlyMine:FBpp0099794,modMine:FBpp0099794; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • FBpp0304645 type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0304645; name=nrv2-PG; parent=FBgn0015777,FBtr0332369; dbxref=FlyBase:FBpp0304645,FlyBase_Annotation_IDs:CG9261-PG,REFSEQ:NP_001260164,GB_protein:AGB92700; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta]
  • [fly-122215-dmel-6-09-contam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0079009; name=nrv2-PC; parent=FBgn0015777,FBtr0079381; dbxref=FlyBase:FBpp0079009,FlyBase_Annotation_IDs:CG9261-PC,GB_protein:AAN10600.1,REFSEQ:NP_477168,GB_protein:AAN10600,UniProt/Swiss-Prot:Q24048; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0099794; name=nrv2-PF; parent=FBgn0015777,FBtr0100382; dbxref=FlyBase_Annotation_IDs:CG9261-PF,FlyBase:FBpp0099794,GB_protein:AAX52659.1,REFSEQ:NP_001014475,GB_protein:AAX52659,UniProt/Swiss-Prot:Q24048,FlyMine:FBpp0099794,modMine:FBpp0099794; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
  • type=protein; loc=2L:complement(join(6796337..6796481,6791701..6791841,6791518..6791637,6791031..6791323,6790799..6790967,6790639..6790742)); ID=FBpp0304645; name=nrv2-PG; parent=FBgn0015777,FBtr0332369; dbxref=FlyBase:FBpp0304645,FlyBase_Annotation_IDs:CG9261-PG,REFSEQ:NP_001260164,GB_protein:AGB92700,UniProt/Swiss-Prot:Q24048; MD5=2bae438d33e9985f9a83deb8e25fa20b; length=323; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
    • Organism: Drosophila melanogaster
    Length: 323 amino acids

    Gene Ontology:
    Cellular Component: septate junction [IDA]
    sodium:potassium-exchanging ATPase complex [IC][ISS]
    plasma membrane [ISS]
    Biological Process: potassium ion transport [IEA]
    sodium ion transport [IEA]
    cation transport [IDA]
    regulation of tube size, open tracheal system [IMP]
    septate junction assembly [IMP]
    establishment of glial blood-brain barrier [IMP]
    regulation of tube diameter, open tracheal system [IMP]
    ATP biosynthetic process [IEA]
    regulation of tube length, open tracheal system [IMP]
    open tracheal system development [IMP]
    Molecular Function: sodium:potassium-exchanging ATPase activity [IMP][ISS][NAS]
    cation transmembrane transporter activity [IDA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPTITEDCID GFQQYYSRPP ERPKKKSLKQ MVYDSEDNSY FGRSMDSWAK IGIFYVAFYG  60
   61 VLAALVAICM WAFFQTLDPR IPKWTLDRSL IGTNPGLGFR PLPPVDNVES TLIWYKGTQH 120
  121 ENYKHWTDSL DDFLAVYKVP GLTPGRGQNI YNCDYNQPPP KGQVCDVDIK TWSPCTKENN 180
  181 YSYHKSAPCI FLKLNKIYGW IPEYYNRSND LPANMPASLK TYIAEVEKTQ PEKLNTIWVS 240
  241 CEGENPADQE NIGAVNYLPI RGFPGYFYPY QNSEGYLSPL VAVHFQRPKR GIIINVECRA 300
  301 WARNIIHDRK ERIGSVHYEL LID

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle